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CREB3L3

Official Full Name

cAMP responsive element binding protein 3-like 3
Overview

CREB3L3 is a liver-specific transcription factor and member of the CREB/ATF transcription factor family (Omori et al.,;2001 (PubMed 11353085)).
Synonyms

CREB3L3; cAMP responsive element binding protein 3-like 3; cyclic AMP-responsive element-binding protein 3-like protein 3; CREB H; cAMP responsive element binding protein 3 like 3; cAMP responsive element-binding protein 3 like protein 3; CREB/ATF family transcription factor; CREBH; Cyclic AMP responsive element binding protein 3 like protein 3; HYST1481; MGC126553; MGC126557; Transcription factor CREB H; transcription factor CREB-H; cAMP-responsive element-binding protein 3-like protein 3; CREB-H;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CREB3L3-7287HCL	Recombinant Human CREB3L3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CREB3L3-2240H	Recombinant Human CREB3L3 Protein (Met1-Thr322), N-His tagged	E.coli	N-His	Met1-Thr322	Inquiry
Mouse	CREB3L3-3890M	Recombinant Mouse CREB3L3 Protein	Mammalian Cell	His		Inquiry
Mouse	CREB3L3-1966M	Recombinant Mouse CREB3L3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CREB3L3-1966M-B	Recombinant Mouse CREB3L3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CREB3L3-1591R	Recombinant Rat CREB3L3 Protein	Mammalian Cell	His		Inquiry
Rat	CREB3L3-1248R	Recombinant Rat CREB3L3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CREB3L3-1248R-B	Recombinant Rat CREB3L3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

CREB3L3 involved in several pathways and played different roles in them. We selected most pathways CREB3L3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CREB3L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
cGMP-PKG signaling pathway	GNAI1;KCNJ8;PRKG2;PPP3CC;IRS1;GNA11;PIK3CB;Adcy4;PPP3CA
cAMP signaling pathway	PLN;ATP1B2;NFATC1;CAMK2D;ORAI1;HCAR2;RAP1B;VAV1;RELA
PIK-Akt signaling pathway	TCL1B;IL3;PRLR;TSC1;GNG13;COL6A6;LPAR2;VEGFA;FGF6
AMPK signaling pathway	AKT2;PIK3R1;ELAVL1;HNF4A;PRKAG1;CCNA2;PRKAG2;PRKAA1;ADIPOR1
Adrenergic signaling in cardiomyocytes	PPP2R3C;ATP1B1B;CACNG6A;MAPK14;ADCY8;ADRB1;PPP2R1A;PRKACB;AKT2L
TNF signaling pathway	AKT2;RIPK1;MAPK12;CCL20;LIF;CFLAR;FAS;CCL2;MAPK9
Cholinergic synapse	CREB3L2;KCNJ6;KCNJ14;GNG13;GNAQ;CHRM4;CAMK4;HRAS;CHRM5
Dopaminergic synapse	PPP2R5D;CAMK2D;CREB3L4;GNAS;MAPK10;GNAO1;MAPK11;PRKCB;CALML5
Insulin secretion	CAMK2G;KCNJ11;CCKAR;ATF4;KCNMB4;KCNN4;ATP1B2;ATP1B1;Adcy4
Estrogen signaling pathway	HSPA1A;PRKACB;CALML5;CALM4;FKBP4;MAP2K1;PIK3CA;GNAI3;PLCB3
Melanogenesis	CREB3L3;WNT9A;Fzd4;TYRP1B;MITF;PLCB1;FZD7;GNAIA;GNAI2A
Thyroid hormone synthesis	GNAQ;TSHR;ATP1B3;ITPR1;HSP90B1;ATP1A4;CREB5;ASGR1;ASGR2
Aldosterone synthesis and secretion	ITPR2;HSD3B4;DDX1;KCNK9;CAMK1D;NETO2;CYP21A1;PRKD3;PLCB3
Insulin resistance	PRKCQ;OGT;SLC2A4;G6PCA.1;RPS6KAL;PPP1CB;PIK3CD;PYGB;RELA
Huntingtons disease	NDUFA4;COX7A1;PLCB4;ATP5B;COX4I1;ATP5F1;POLR2F;ATP5G1;mt-Atp8
Cocaine addiction	GRIN3B;GRIN2C;PRKACG;CREB3L2;FOSB;GRIN2A;GNAI1;PRKACA;GRIN3A
Alcoholism	CREB5;SOS1;CALM1;CREB3L2;HIST3H3;HIST4H4;HIST1H3D;GNAI2;HIST1H4A
Hepatitis B	BCL2;NFATC3;EGR2;STAT5B;MAVS;NFATC4;PTEN;BIRC5;PIK3R5
Viral carcinogenesis	GTF2H2C_2;PIK3R3;SP100;HIST1H2BO;CDC20;HIST1H2BA;ACTN1;TBPL1;UBE3A
Prostate cancer	IGF1R;TP53;ATF4;PIK3R1;SOS1;CCNE2;Pdgfa&Pdgfb;CCNE1;PDGFC

CREB3L3 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, cAMP response element binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CREB3L3 itself. We selected most functions CREB3L3 had, and list some proteins which have the same functions with CREB3L3. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II regulatory region sequence-specific DNA binding	ARHGAP35;TFAP2C;SP1;CDX1B;DMBX1;ALX1;STAT4;ETV3;HOXD8
cAMP response element binding	ATF6;CREB3L1;CREB1;CREB3L4;CREB3;E4F1;ATF6B;ATF2;JUN
protein binding	SYNE1;PPP1R15B;CAPNS1;GFI1B;TERF2;DCTN4;PCDH17;FAM71C;ACVR1B
protein heterodimerization activity	HIST1H2B8;SRY;PIK3R2;IKBKG;HER1;GM5506;NFYBB;CXorf15;NR4A2
protein homodimerization activity	GIMAP7;PRLR;UNC13A;OSTA;GOT2;ABAT;MAP3K9;IKZF3;MTHFD1L
transcription regulatory region sequence-specific DNA binding	CRY2;NR5A1;SUV39H1;GATA3;NFE2L1A;MEF2AA;MKL1;TBX18;NKX3-1
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	NR1I3;MAFGB;RAD21;MSGN1;ETV5;PKNOX1;GATA6;MAFG;MAF

CREB3L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CREB3L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CREB3L3.

ATF6; CREB3; CREB1; NFIL3; RIOK3; KPNA2; KHDRBS1; BAD; USP7; PELI2