creb3l3
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  • Official Full Name
  • cAMP responsive element binding protein 3-like 3
  • Background
  • CREB3L3 is a liver-specific transcription factor and member of the CREB/ATF transcription factor family (Omori et al.,;2001 (PubMed 11353085)).
  • Synonyms
  • CREB3L3; cAMP responsive element binding protein 3-like 3; cyclic AMP-responsive element-binding protein 3-like protein 3; CREB H; cAMP responsive element binding protein 3 like 3; cAMP responsive element-binding protein 3 like protein 3; CREB/ATF family transcription factor; CREBH; Cyclic AMP responsive element binding protein 3 like protein 3; HYST1481; MGC126553; MGC126557; Transcription factor CREB H; transcription factor CREB-H; cAMP-responsive element-binding protein 3-like protein 3; CREB-H
Cat.#:CREB3L3-3890MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CREB3L3 Protein
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Cat.#:CREB3L3-1591RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CREB3L3 Protein
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Cat.#:CREB3L3-7287HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CREB3L3 293 Cell Lysate
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Involved Pathway

CREB3L3 involved in several pathways and played different roles in them. We selected most pathways CREB3L3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CREB3L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cGMP-PKG signaling pathway
ATP2A2; CALM4; FXYD2; CALML5; PPP1CC; PPP3R2; SLC25A31; VDAC3; CREB5; CALM1
cAMP signaling pathway
HHIP; GRIA4; CALM2; ATP2B4; FXYD1; GIPR; PIK3CA; FSHB; FFAR2; GHSR
PIK-Akt signaling pathway
IFNA5; LPAR5; INS; IBSP; FGF4; GH1; ITGAV; TSC1; RELA; IFNA7
AMPK signaling pathway
PIK3R2; ELAVL1; PPP2R2C; PIK3CD; PPP2R2D; CREB3L2; RHEB; ACACB; PPP2R1A; AKT1
Adrenergic signaling in cardiomyocytes
CALM1B; CACNG1; ADRB2B; ADCY7; MAPK12; ADCY2B; ADCY1; AKT2; ATP1B4; CACNA2D2
TNF signaling pathway
MAPK8; TNFRSF1A; AKT1; TNF; IL18R1; PIK3CB; CASP7; CCL20; MAP3K14; RPS6KA5
Cholinergic synapse
CHRM4; GNG8; JAK2; PLCB4; SLC5A7; GNB2; CHRM5; KCNJ2; CREB3L4; GNG7
Dopaminergic synapse
GNG7; CALML5; SLC18A1; GNG13; FOS; ARRB2; CALM1; PPP2R1A; CALY; CALM3
Insulin secretion
CAMK2A; STX1A; PLCB2; KCNJ11; ATP1A4; KCNN4; PRKCB; KCNMB3; ATF4; PLCB4
Estrogen signaling pathway
RAF1; ATF6B; PRKCD; ESR2; CALML3; PLCB4; PIK3R3; GNAQ; CALM2; CREB3L1
Melanogenesis
MITFA; KITB; GNA15.1; GNAI2; KITLGB; FZD6; LEF1; GNAI2B; GNAI3; CREB3L2
Thyroid hormone synthesis
GNAQ; TPO; PRKCG; Adcy4; ATP1A1; PRKACA; SLC26A4; GPX1; PRKCA; ATP1A2
Glucagon signaling pathway
CALM4; CAMK2G; PRKACG; PPP3R1; PHKG2; AKT2; ACACB; ITPR1; PDHA2; PYGB
Aldosterone synthesis and secretion
PRKACA; ATF2; PRKACG; HSD3B1; SCARB1; ORAI1; KCNK3; ATF4; GNAS; CACNA1H
Insulin resistance
GSK3AA; SLC2A1; NFKBIAB; RPS6KB1; SLC27A1B; MAPK8; PRKCD; PIK3CB; PIK3R3A; PRKAG1
Vasopressin-regulated water reabsorption
ARHGDIB; DYNC1LI2; RAB11B; STX4; CREB5; AQP3; PRKACA; DYNC1I1; PRKACB; CREB3L2
Huntingtons disease
UQCRC1; NDUFA11; NDUFA13; SOD2; DNAL4; VDAC1; TBPL2; HAP1; COX7C; NDUFS8
Cocaine addiction
CREB3L2; PRKACA; SLC18A2; DRD1; PRKACB; ATF6B; PRKACG; GRIN2B; GNAI1; DRD1A
Amphetamine addiction
PPP3CA; PPP1CA; SLC14A2; PRKACB; PRKACG; NETO2; GRIN2B; GRIA1; CREB5; CALM1
Alcoholism
HIST1H2AO; HIST2H4A; NRAS; GNAI3; HIST1H2BD; H2AFB2; GRIN2C; GM14476; HIST1H2AI; HIST4H4
Hepatitis B
PTEN; IFNA8; ELK1; IFNA6; CREB3L3; RELA; TGFB2; STAT2; PTK2B; TLR3
Viral carcinogenesis
GTF2E1; RAC1; ACTN4; NFKB2; PIK3CD; BAX; HLA-A; MAPK1; CREB3L3; GTF2H4
Prostate cancer
PIK3CA; IKBKG; PIK3R3; Ar; SOS1; SPRY1; PDGFRA; ARAF; TRP53; GRB2

Protein Function

CREB3L3 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, cAMP response element binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CREB3L3 itself. We selected most functions CREB3L3 had, and list some proteins which have the same functions with CREB3L3. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein CREB3; EAF2; RXRA; DMRT1; RARA; ZBTB16A; ZSCAN20; ETV6; BCL6AB; ZNF256
Function cAMP response element binding
Related Protein ATF6B; CREB3; E4F1; CREB3L3; ATF6; CREB3L3A; CREB3L4; JUN; CREB3L2; CREB3L1
Function protein binding
Related Protein CYP2S1; RBKS; HMG20A; ALDH3A1; EFCAB4B; RITA1; RHO; NUP50; GPANK1; SERPINB5
Function protein heterodimerization activity
Related Protein PEF1; EPAS1; TAF9; RXRA; ATF4; TAF12; TAS1R1; PDX1; ATF1; PPP1CBL
Function protein homodimerization activity
Related Protein TENM3; STK25; FLT3; RNF40; ADRA2A; CIDEA; VEGFA; EIF2AK3; PVRL2; ENO2
Function transcription regulatory region sequence-specific DNA binding
Related Protein NFE2; MEF2AA; PER2; ZNF658; ARNTL; SOX4; NKX3; NFKB1; GATA3; SUV39H1
Function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein EAF2; STAT3; STAG2; ATF5; LEF1; ONECUT3; STAG1; FOXF1; MAFBA; ALX1

Interacting Protein

CREB3L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CREB3L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CREB3L3.
ATF6; CREB3; CREB1; NFIL3; RIOK3; KPNA2; KHDRBS1; BAD; USP7; PELI2