CYP2W1

  • Official Full Name

    cytochrome P450, family 2, subfamily W, polypeptide 1

  • Overview

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

  • Synonyms

    CYP2W1;cytochrome P450, family 2, subfamily W, polypeptide 1;cytochrome P450 2W1;FLJ20359;MGC34287;CYPIIW1

Recombinant Proteins

  • Human
  • Mouse
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Flag
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CYP2W1-2271H Recombinant Human CYP2W1 Protein, GST-tagged Wheat Germ Human GST
CYP2W1-4204M Recombinant Mouse CYP2W1 Protein Mammalian Cells Mouse His
CYP2W1-7107HCL Recombinant Human CYP2W1 293 Cell Lysate HEK293 Human Non
CYP2W1-1740HFL Recombinant Full Length Human CYP2W1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
CYP2W1-2152M Recombinant Mouse CYP2W1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CYP2W1-2152M-B Recombinant Mouse CYP2W1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CYP2W1-2396HF Recombinant Full Length Human CYP2W1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 434 amino acids
Cyp2w1-2420M Recombinant Mouse Cyp2w1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
CYP2W1-705H Recombinant Human CYP2W1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
CYP2W1-705H-B Recombinant Human CYP2W1 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    CYP2W1 involved in several pathways and played different roles in them. We selected most pathways CYP2W1 participated on our site, such as Biological oxidations,Cytochrome P450 - arranged by substrate type,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP2W1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biological oxidations CYP4T8,CYP2K17,CYP2C9,CYP19A1,DPEP1,CYP2K16,UGT1B2,GGTLC1,CYP2Y3,GGT6
    Cytochrome P450 - arranged by substrate type CYP8B2,CYP27B1,CYP4T8,CYP2A13,CYP2Y3,POMCB,CYP2C19,CYP21A2,CYP19A1,CYP2N13
    metapathway biotransformation NAT8B,NAA30,CYP4Z1,HS3ST6,PRKRA,SULT6B1,CYP20A1,NAA40,GAL3ST3,CHST8
    cytochrome P450 CYB5R3,CYP4V2,CYP4Z1,CYP4F12,POR,CYP2A7,CYB5A,CYP20A1,CYB5B
    Phase 1 - Functionalization of compounds ADH8A,CES1,CYP2V1,CYP2K18,CYP3C4,CYP3A7-CYP3AP1,CYP3A7,CYP2AD2,CYP8B2,CYP2K16
    Metabolism NUDT3A,PRKRA,MED9,SLC25A12,UCP2,SLC25A21,COX14,SLC25A32,NDUFAF4,NEU3
    Xenobiotics CYP2A7,CYP3C1,CYP3C4
    Miscellaneous substrates CYP2K17,CYP2S1,CYP2K8,CYP4F22,CYP3C1,CYP2K6,CYP4B1,CYP2U1,CYP2K19,CYP2K22

    Protein Function

    CYP2W1 has several biochemical functions, for example, heme binding,iron ion binding,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP2W1 itself. We selected most functions CYP2W1 had, and list some proteins which have the same functions with CYP2W1. You can find most of the proteins on our site.

    Function Related Protein
    steroid hydroxylase activity CYP2A4,CYP2X10.2,CYP2AA1,CYP46A1.2,CYP2C50,CYP2J5,CYP2X7,CYP2K18,CYP2C39,CYP2B6
    oxygen binding CYP26A1,CYP2K6,CYP2AA7,CYP2AA4,CYP2E1,CYP2X7,CYP2P6,CYP3A4,BA1,HBA-X
    iron ion binding CYP17A2,CYP2AD6,TET1,CYP39A1,NOS3,CYP4V7,HBAA,CYP4V2,CYP2A12,CYP2C18
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen CYP2X7,CYP2A4,CYP2C8,CYP2F1,CYP2D26,CYP2C18,CYP2C55,CYP2B19,CYP2K6,CYP2S1
    heme binding NENF,CYP4F3,CYB5B,CYP2AA3,HBG2,CYP2F1,NGB,CYP21A2,HBBE1.1,CYP2C39

    Interacting Protein

    CYP2W1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP2W1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP2W1.

    CYB5A;ZBTB26

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