dapk2
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  • Official Full Name
  • death-associated protein kinase 2
  • Background
  • This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis.It uses multiple polyadenylation sites.
  • Synonyms
  • DAPK2; death-associated protein kinase 2; DRP 1; MGC119312; DAP kinase 2; DAP-kinase-related protein 1 beta isoform; DRP1; DRP-1
Cat.#:DAPK2-2339HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DAPK2 Protein, GST-tagged
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Cat.#:DAPK2-26805THTag:
Source (Host):Species:Human
Product nameRecombinant Human DAPK2
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Cat.#:DAPK2-290HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DAPK2, GST-tagged, Active
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Cat.#:DAPK2-4305MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DAPK2 Protein
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Cat.#:DAPK2-675HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Death-Associated Protein Kinase 2, His-tagged
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Cat.#:DAPK2-7076HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DAPK2 293 Cell Lysate
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Involved Pathway

DAPK2 involved in several pathways and played different roles in them. We selected most pathways DAPK2 participated on our site, such as Pathways in cancer, Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pathways in cancer
FGF3; WNT3; VHL; ITGB1; WNT5B; AGTR1A; ARNT2; LAMA2; GNGT2; CSF1R
Bladder cancer
MMP9; TRP53; UPK3A; CDKN2A; TP53; MMP1; MMP1A; HRAS; DAPK3; MAP2K2

Protein Function

DAPK2 has several biochemical functions, for example, ATP binding, calmodulin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK2 itself. We selected most functions DAPK2 had, and list some proteins which have the same functions with DAPK2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein KIF17; LACE1; NIM1K; ROCK2B; NUAK1; ACSM2; MOV10; NEK10; CLK4B; DHX8
Function calmodulin binding
Related Protein KCNQ3; CAMSAP1L1; RRAD; TRPV5; ATPIF1; REM1; DCX; PCP4; CNGA2; RYR3
Function identical protein binding
Related Protein BIRC5; COL7A1; RALYL; BNIP2; B2M; IL12B; SOD2; PON2; VIM; HCN2
Function protein binding
Related Protein MYO1C; TRIM5; AMPH; HOXB6; ANTXR1; KLRK1; BLZF1; GFPT2; CXCL10; THEG
Function protein serine/threonine kinase activity
Related Protein STK32A; PAK4; PDK3; NEK5; RAF1; STK40; RIPK4; LRRK1; RPS6KC1; MAST2

Interacting Protein

DAPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK2.
FAM9B; Bub1; LLGL2; KLC3; TUBGCP5; RACGAP1