DTX3L

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DTX3L

Official Full Name deltex 3-like
Background DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
Synonyms DTX3L; deltex 3-like (Drosophila); E3 ubiquitin-protein ligase DTX3L; BBAP; rhysin 2; rhysin2; rhysin-2; B-lymphoma- and BAL-associated protein
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DTX3L-12193H Recombinant Human DTX3L, GST-tagged E.coli GST
    Human DTX3L-2909H Recombinant Human DTX3L Protein, GST-tagged Wheat Germ GST
    Human DTX3L-6792HCL Recombinant Human DTX3L 293 Cell Lysate HEK293 N/A
    Mouse DTX3L-4859M Recombinant Mouse DTX3L Protein Mammalian Cell His

    DTX3L involved in several pathways and played different roles in them. We selected most pathways DTX3L participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System TRAF7; RBCK1; UBE2V1; FRS2A; SH2D1B; CSK; UFL1; CD200; LILRA3; KIF5B
    Antigen processing: Ubiquitination &amp ASB3; MKRN1; TRIM39; LRRC41; RNF41; RNF182; PJA1; KLHL20; ASB13; UBE2U
    Proteasome degradation UBR1; VPRBP; TRIM69; HUWE1; ASB14; TRIM11; ASB6; TRAF7; ASB18; UBE2F
    Class I MHC mediated antigen processing &amp CTSS; GAN; SEC24A; RNF14; ASB8; LRRC41; TRIM9; UBE2U; FBXO44; BLMH
    presentation CTSL2; CD207; ASB2; TRIM11; ASB11; UFL1; FCGR1B; RNF25; UBE2L6; LTN1
    Immune System SIGLEC6; KIF15; BAIAP2; SIGLEC9; ADAR; RNF34; BLMH; CR1; LRR1; DCTN3
    Notch Signaling Pathway MAML1; MFAP2; DLK1; NOTCH1A; JAG1B; JAG1A; NCSTN; SNW1; DVL1B; EP300

    DTX3L has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX3L itself. We selected most functions DTX3L had, and list some proteins which have the same functions with DTX3L. You can find most of the proteins on our site.

    Function Related Protein
    histone binding HIST1H4A; HIST1H3A; ATAD2; PHF21B; TONSL; USP49; HIST1H4F; NPM2; HAT1; ZMYND11
    ligase activity UBE2D1B; MARCH8; CCNB1IP1; UBE2F; UHRF2; MSL2; E4F1; MYLIP; NEDD4; MGRN1
    protein binding MRAP; VCL; POLR3F; RCAN3; SLC9A3; MRPL51; CCT6A; TAF7; TRAPPC4; MYH10
    ubiquitin-protein transferase activity UBE2C; MUL1; ZFP91; TRIM69; MDM2; UBE2T; RFWD3; CBLB; UBA7; UBR4
    zinc ion binding MAN2B1; PIAS4; TRIM35-30; SIVA1; MMP17; ZBTB32; PRKCB; BRF1A; CHURC1; CSRP1B

    DTX3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX3L.

    SPG21; HIP2; UBE2D1; UBE2E1; UBE2D3; UBE2H; UBE2D2; UBE2I; RNF111; UBE2R2; UBE2E3; UBE2W; UBE2E2; PHF7; TRIM9; UBE2D4; MCM7

    Holleman, J; Marchese, A; et al. The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4. MOLECULAR BIOLOGY OF THE CELL 25:1892-1904(2014).
    Bachmann, SB; Frommel, SC; et al. DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. MOLECULAR CANCER 13:-(2014).

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