E2F4

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E2F4

Official Full Name E2F transcription factor 4, p107/p130-binding
Background The E2F family of transcrIPPtion factors regulates gene expression following heterodimerization with the DP family proteins, which promote transition to S phase from G1 phase. E2F activity is controlled by interactions with the retinoblastoma tumor suppre
Synonyms E2F4; E2F transcription factor 4, p107/p130-binding; transcription factor E2F4; E2F 4; p107/p130-binding protein; E2F-4
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human E2F4-12248H Recombinant Human E2F4, GST-tagged E.coli GST
    Human E2F4-3008H Recombinant Human E2F4 Protein, GST-tagged Wheat Germ GST
    Human E2F4-6741HCL Recombinant Human E2F4 293 Cell Lysate HEK293 N/A
    Mouse E2F4-4933M Recombinant Mouse E2F4 Protein Mammalian Cell His
    Rhesus Macaque E2F4-1367R Recombinant Rhesus monkey E2F4 Protein, His-tagged Mammalian Cell His
    Chicken E2F4-1270C Recombinant Chicken E2F4 Mammalian Cell His
    Zebrafish E2F4-12603Z Recombinant Zebrafish E2F4 Mammalian Cell His
    Kit-0318 E2F4 Gene Knockdown Quantification Kit N/A

    E2F4 involved in several pathways and played different roles in them. We selected most pathways E2F4 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with E2F4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis NR1H3; NCOA2; EGR2; CTNNB1; CEBPD; NAMPT; E2F4; STIL; CYP26A1; GATA2A
    Cell Cycle RAD50; CEP57; DHFR; POLD3; LIN9; NUDC; ORC6L; DKC1; YWHAE1; SKA1
    Cell Cycle, Mitotic CSNK1D; CENPA; SSNA1; KNTC1; RBBP4; ODF2B; CEP135; PDS5A; DYRK1A; STAG2
    Cyclin D associated events in G1 PIANP; CDK7; CDKN2B; CDKN2D; CKS1B; CDKN2C; E2F4
    E2F transcription factor network HIC1; PRMT5; CDKN2C; SMARCA2; CEBPA; E2F4; YY1; CES3; RYBP; DHFR
    G0 and Early G1 LIN54; DYRK1A; E2F4; LIN37; TOP2A; LIN52; LIN9; MYBL2; PIANP
    G1 Phase CDKN2D; CDKN2B; CKS1B; CDKN2C; E2F4; PIANP

    E2F4 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by E2F4 itself. We selected most functions E2F4 had, and list some proteins which have the same functions with E2F4. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HER1; MCM3L; TRIM27; ZFP574; SOX2; E2F4; ZNF398; NKX3.3; EEPD1; MGMT
    RNA polymerase II core promoter proximal region sequence-specific DNA binding ETS2; FEZF2; ZNF114; CEBPG; GMEB1; NR5A2; NKX2; POU3F2; NFATC3; MEF2B
    protein binding BRD3; CCDC13; GRIFIN; DSN1; MEI4; TNIP2; FRMD4B; JAK1; PIM3; SETD2
    protein domain specific binding ICA1; ARRB2; CACNB2; DDX20; GABRR3; CALM2; PRKAR2B; TJP1; CTBP1; NLRP1
    transcription factor activity, sequence-specific DNA binding ZNF484; CIR1; RUNX1T1; SALL4; GLIS2; NR6A1B; CREB3; ZNF613; STAT1B; NME2
    transcription factor binding RNF222; HAND1; IGHMBP2; MAPK1; TRERF1; TFDP1A; FOXO4; TNFRSF10A; EPN1; C1QBP
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GMEB1; NPAS4; RUNX2; TP73; RBPJ; ZIC1; NFYC; ETV4; NDN; BCL11B

    E2F4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with E2F4 here. Most of them are supplied by our site. Hope this information will be useful for your research of E2F4.

    RBL2; TFDP2; LIN9; RB1; E7; MYBL2; RBL1; TFDP1

    Demyanenko, SV; Uzdensky, AB; et al. PDT-induced epigenetic changes in the mouse cerebral cortex: A protein microarray study. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1840:262-270(2014).
    Yin, D; Xie, D; et al. DLK1: increased expression in gliomas and associated with oncogenic activities. ONCOGENE 25:1852-1861(2006).

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