eme2
Share
  • Official Full Name
  • essential meiotic endonuclease 1 homolog 2 (S. pombe)
  • Synonyms
  • 2810013J18Rik
Cat.#:EME2-3276HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EME2 Protein, GST-tagged
+Inquiry
Cat.#:EME2-1020HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human EME2
+Inquiry
Cat.#:EME2-5172MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EME2 Protein
+Inquiry

Involved Pathway

EME2 involved in several pathways and played different roles in them. We selected most pathways EME2 participated on our site, such as DNA Double-Strand Break Repair, DNA Repair, Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EME2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA Double-Strand Break Repair
TP53BP1; KDM4B; TDP2B; TOPBP1; RIF1; WRN; PARP2; TIMELESS; RNF168; KIAA0146
DNA Repair
COPS7A; BRE; FUZ; UIMC1; DCLRE1A; RAD51AP1; BAZ1B; ALKBH3; EYA3; ZNF830
Fanconi Anemia Pathway
RMI2; SLX1B; BRIP1; EME2; ZBTB32; FANCE; MUS81; TOP3B; BLM; ATRIP
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)
RNF4; HUS1; PPP4CA; PPP4R2A; RBBP8; UIMC1; TOPBP1; RAD51AP1; BRCC3; RAD9
HDR through Homologous Recombination (HRR)
HUS1; RHNO1; TOPBP1; RAD51AP1; KIAA0146; EME2; EME1; RBBP8; GEN1; RTEL1
Homology Directed Repair
GEN1; TIMELESS; FUZ; WRN; RHNO1; EME2; PPP4R2A; PPP4R2B; TOPBP1; TIPIN
Resolution of D-Loop Structures
RTEL1; RAD51AP1; GEN1; EME2; KIAA0146

Protein Function

EME2 has several biochemical functions, for example, DNA binding, endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EME2 itself. We selected most functions EME2 had, and list some proteins which have the same functions with EME2. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF26; TIGD5; ZNF692; ZFP821; FOXO1A; SOX15; POLR2F; KIF22; HIST1H2AI; ZIC5
Function endonuclease activity
Related Protein RNASEL3; ANG; ZRANB3; ENDOG; RNASE3; ERN2; PMS2; RNASEL2; CENPT; EME2

Interacting Protein

EME2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EME2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EME2.
FEN1

EME2 Related Articles

Pepe, A; West, SC; et al. MUS81-EME2 Promotes Replication Fork Restart. CELL REPORTS 7:1048-1055(2014).
Pepe, A; West, SC; et al. Substrate specificity of the MUS81-EME2 structure selective endonuclease. NUCLEIC ACIDS RESEARCH 42:3833-3845(2014).