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EME2

  • Official Full Name

    essential meiotic endonuclease 1 homolog 2 (S. pombe)

  • Synonyms

    2810013J18Rik;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EME2-1020H Recombinant Human EME2 Mammalian Cell His
Human EME2-3276H Recombinant Human EME2 Protein, GST-tagged Wheat Germ GST
Human EME2-4241HF Recombinant Full Length Human EME2 Protein, GST-tagged In Vitro Cell Free System GST 444 amino acids
Human EME2-2848H Recombinant Human EME2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EME2-2848H-B Recombinant Human EME2 Protein Pre-coupled Magnetic Beads HEK293
Mouse EME2-5172M Recombinant Mouse EME2 Protein Mammalian Cell His
Mouse EME2-2769M-B Recombinant Mouse EME2 Protein Pre-coupled Magnetic Beads HEK293
Mouse EME2-2769M Recombinant Mouse EME2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EME2 Related Articles

EME2 involved in several pathways and played different roles in them. We selected most pathways EME2 participated on our site, such as DNA Double-Strand Break Repair, DNA Repair, Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EME2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA Double-Strand Break RepairTHRSP;EYA2;RTEL1;PPP4R2B;DNA2;KDM4A;PPP4CB;RAD51AP1;PPP4R2A
DNA RepairCLSPN;BRE;PPP4CB;TCEA1;TDP1;PARP1;DCLRE1A;PIAS3;KDM4A
Fanconi Anemia PathwayFANCE;FANCB;RPA2;RAD51;TELO2;POLK;POLH;SLX4;RMI1
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)RAD9;KIAA0146;EME2;BRE;HUS1;RBBP8;THRSP;RHNO1;RNF168
HDR through Homologous Recombination (HRR)FUZ;EME1;WRN;RBBP8;KIAA0146;GEN1;RAD9B;RHNO1;RTEL1
Homology Directed RepairRAD51AP1;RHNO1;EME1;PPP4R2B;PPP4CB;TOPBP1;RTEL1;WRN;KIAA0146
Resolution of D-Loop StructuresKIAA0146;EME2;RAD51AP1;GEN1;RTEL1

EME2 has several biochemical functions, for example, DNA binding, endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EME2 itself. We selected most functions EME2 had, and list some proteins which have the same functions with EME2. You can find most of the proteins on our site.

Function Related Protein
DNA bindingJUNBB;ELMSAN1A;ANG3;ZNF212;ARNTL1A;STRBP;RCOR2;REV3L;XRCC6
endonuclease activityEAR5;RNASE7;ANG4;ZRANB3;RNASE6;DNASE2A;EAR1;ENDOG;EME1

EME2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EME2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EME2.

FEN1

Pepe, A; West, SC; et al. MUS81-EME2 Promotes Replication Fork Restart. CELL REPORTS 7:1048-1055(2014).
Pepe, A; West, SC; et al. Substrate specificity of the MUS81-EME2 structure selective endonuclease. NUCLEIC ACIDS RESEARCH 42:3833-3845(2014).
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