epn1
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  • Official Full Name
  • epsin 1
  • Background
  • The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • EPN1; epsin 1; epsin-1; EH domain binding mitotic phosphoprotein; EPN 1; EPS 15 interacting protein 1; EPS-15-interacting protein 1; EH domain-binding mitotic phosphoprotein
Cat.#:EPN1-3415HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPN1 Protein, GST-tagged
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Cat.#:EPN1-1633HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPN1 protein, His-tagged
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Cat.#:EPN1-5257MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EPN1 Protein
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Cat.#:EPN1-2125RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EPN1 Protein
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Cat.#:EPN1-12541ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EPN1
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Cat.#:EPN1-6581HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EPN1 293 Cell Lysate
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Involved Pathway

EPN1 involved in several pathways and played different roles in them. We selected most pathways EPN1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPN1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
DNM2A; ACAP3; TGFBR2; TGFBR1A; PDCD6IP; CHMP6B; ITCHA; IGF2R; RLN1; SH3GL3B

Protein Function

EPN1 has several biochemical functions, for example, ion channel binding, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPN1 itself. We selected most functions EPN1 had, and list some proteins which have the same functions with EPN1. You can find most of the proteins on our site.
Function
Related Protein
Function ion channel binding
Related Protein PACS1A; KCNQ1; PIRT; PDE4D; KCNE2; FKBP1A; ID2; PACS1; EPN1; CALM
Function lipid binding
Related Protein PLUNC; FABP10A; FFAR3; LTC4S; SEC14L3; PAQR7B; EPN1; AMER2; Ar; FABP5
Function protein binding
Related Protein PLEKHB1; MOBP; FIS1; RBMX2; SPIN1; SLC6A12; MAPK15; PVR; GRB2; PTGES3
Function transcription factor binding
Related Protein ARID5A; ZFPM2; POU5F1; PIK3R1; HDAC5; TNFRSF10A; HMGA1; MED12L; MYC; ARHGEF2

Interacting Protein

EPN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPN1.
REPS2; DAZAP2; PLEKHB2; VCAM1; UBA1; EPS15; UBE2N; UBE2V1; Map3k1; LAPTM5; CRMP1; npr

EPN1 Related Articles

Benhra, N; Vignaux, F; et al. Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells. MOLECULAR BIOLOGY OF THE CELL 21:2078-2086(2010).
Jakobsson, J; Gad, H; et al. Role of epsin 1 in synaptic vesicle endocytosis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:6445-6450(2008).
Khanna, R; Li, Q; et al. 'Fractional Recovery' Analysis of a Presynaptic Synaptotagmin 1-Anchored Endocytic Protein Complex. PLOS ONE 1:-(2006).
Han, ZZ; Karatan, E; et al. Accelerated screening of phage-display output with alkaline phosphatase fusions. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 7:55-62(2004).