ELAC1
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Official Full Name
elaC homolog 1 (E. coli) -
Overview
ElaC homolog protein 1 (ELAC1) is a zinc phosphodiesterase, which displays some tRNA 3-processing endonuclease activity. It is probably involved in tRNA maturation, by removing a 3 trailer from precursor tRNA. -
Synonyms
ELAC1;elaC homolog 1 (E. coli);elaC (E. coli) homolog 1;zinc phosphodiesterase ELAC protein 1;D29;tRNA Z (short form);Deleted in Ma29;ELAC 1;ElaC homolog 1;ElaC homolog protein 1;Ribonuclease Z 1;RNase Z 1;tRNA 3 endonuclease 1;tRNA Z;tRNase Z 1;tRNase ZS;OTTHUMP00000163547;tRNA 3 processing endoribonuclease
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Wheat Germ
- Mammalian Cells
- E.coli
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ELAC1-3227H | Recombinant Human ELAC1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ELAC1-5120M | Recombinant Mouse ELAC1 Protein | Mammalian Cells | Mouse | His |
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| ELAC1-944Z | Recombinant Zebrafish ELAC1 | Mammalian Cells | Zebrafish | His |
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| ELAC1-96H | Recombinant Human ELAC1, His-tagged | E.coli | Human | His |
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| ELAC1-6639HCL | Recombinant Human ELAC1 293 Cell Lysate | HEK293 | Human | Non |
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| ELAC1-2236H | Recombinant Human ELAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| ELAC1-2729M | Recombinant Mouse ELAC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ELAC1-2729M-B | Recombinant Mouse ELAC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ELAC1-4329HF | Recombinant Full Length Human ELAC1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 363 amino acids |
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| Elac1-520M | Recombinant Mouse Elac1 Protein, MYC/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
ELAC1 involved in several pathways and played different roles in them. We selected most pathways ELAC1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELAC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | MAGOHB,EEF1A1L1,EIF3G,KPNB1,PAIP1,EIF4G1A,EIF4A1A,PABPC1L,EIF4G3,RANGAP1 |
Protein Function
ELAC1 has several biochemical functions, for example, 3-tRNA processing endoribonuclease activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELAC1 itself. We selected most functions ELAC1 had, and list some proteins which have the same functions with ELAC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-tRNA processing endoribonuclease activity | ELAC2 |
| metal ion binding | MAP2K5,TRAFD1,RNF148,CYP21A1,CAR13,ZDHHC6,GTSF1,ZNF684,THRAA,KIT |
Interacting Protein
ELAC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELAC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELAC1.
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References
- Huhn, S; Bevier, M; et al. Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors. CANCER CAUSES & CONTROL 25:759-769(2014).
- Rossmanith, W; et al. Localization of Human RNase Z Isoforms: Dual Nuclear/Mitochondrial Targeting of the ELAC2 Gene Product by Alternative Translation Initiation. PLOS ONE 6:-(2011).
