This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.
FAM161A; family with sequence similarity 161, member A; retinitis pigmentosa 28 (autosomal recessive) , RP28; protein FAM161A; FLJ13305; retinitis pigmentosa 28 (autosomal recessive); RP28; MGC129982; MGC129983
FAM161A has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM161A itself. We selected most functions FAM161A had, and list some proteins which have the same functions with FAM161A. You can find most of the proteins on our site.
Function protein binding
Related Protein CCL11; C1orf116; GH1; AGAP2; VAV2; R3HDM2; MYO5B; KLRD1; COL4A3BP; TYR
FAM161A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM161A here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM161A.
CCDC102B; FSD2; EHMT2; CADPS; 80125
FAM161A Related Articles
Karlstetter, M; Sorusch, N; et al. Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. HUMAN MOLECULAR GENETICS 23:5197-5210(2014).
Roosing, S; Lamers, IJC; et al. Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy. AMERICAN JOURNAL OF HUMAN GENETICS 95:131-142(2014).