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FAM84B

  • Official Full Name

    family with sequence similarity 84, member B

  • Overview

    FAM84B belongs to the FAM84 family. It is expressed in esophageal squamous cell carcinomas.
  • Synonyms

    FAM84B; family with sequence similarity 84, member B; protein FAM84B; BCMP101; breast cancer membrane associated protein 101; neurological/sensory 2; NSE2; BF642811; D330050I23Rik; Breast cancer membrane protein 101; Breast cancer membrane-associated protein 101; FA84B_HUMAN; Family with sequence similarity 84 member B; OTTHUMP00000228215; Protein NSE2; RGD1562236;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FAM84B-3809H Recombinant Human FAM84B Protein, GST-tagged Wheat Germ GST
Human FAM84B-12729H Recombinant Human FAM84B, His-tagged E.coli His 1-310a.a.
Human FAM84B-2442H Recombinant human FAM84B, His-tagged E.coli His
Human FAM84B-6342HCL Recombinant Human FAM84B 293 Cell Lysate HEK293 N/A
Human FAM84B-4648HF Recombinant Full Length Human FAM84B Protein, GST-tagged In Vitro Cell Free System GST 310 amino acids
Zebrafish FAM84B-3992Z Recombinant Zebrafish FAM84B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FAM84B Related Articles

FAM84B involved in several pathways and played different roles in them. We selected most pathways FAM84B participated on our site, such as Aflatoxin B1 metabolism, Aflatoxin activation and detoxification, Benzo(a)pyrene metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM84B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aflatoxin B1 metabolismFAM84B;CYP2A13;CYP1A2;PRKRA;CYP3A4
Aflatoxin activation and detoxificationDPEP1;PRKRA;GGTLC1;CYP1A2;CYP3C1;GGT6;FAM84B;CYP3A5;CYP2Y3
Benzo(a)pyrene metabolismCYP1B1;FAM84B;AKR1C4;AKR1C2;CYP3A4;AKR1A1;CYP1A1
Bile secretionKCNN2;ATP1A1;AQP8;ATP1B4;SLCO1A5;GNAS;LDLR;SLC10A1;SLC9A3
Biological oxidationsFDX1;CYP2B6;ADH1C;CYP2AD2;CYP4F22;CYP4B1;CYP2F1;CYP3C1;ACY3
Chemical carcinogenesisGSTM6;CYP3A7;SULT1A2;GSTM2;CYP3A7-CYP3AP1;UGT1A6A;SULT2A1;CCBL1;ALDH3A1
Cytochrome P450 - arranged by substrate typeCYP2K18;CYP8B2;CYP2A7;CYP2E1;CYP3A7;CYP2A6;CYP4F12;CYP17A1;CYP2K19

FAM84B has several biochemical functions, for example, aromatase activity, caffeine oxidase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM84B itself. We selected most functions FAM84B had, and list some proteins which have the same functions with FAM84B. You can find most of the proteins on our site.

Function Related Protein
aromatase activityCYP2C55;CYP2S1;CYP2C70;CYP4Z1;CYP2B19;CYP1A;CYP2D6;CYP1D1;CYP3A5
caffeine oxidase activityFAM84B;CYP2C38;CYP2C39;CYP2C9;CYP3A4;CYP1A2
enzyme bindingSTUB1;LAMB1;NOXA1;CTNNB1;HMGA1;HAND1;CAV1;TP53;CYP2A4
heme bindingCYP46A1.2;HBAD;CYP4F14;CYP3A4;HBA-X;CYP2C39;CYP1A;MPO;TPO
iron ion bindingCYP3A25;CYP4A12A;CYP2X8;HBG1;P3H2;JMJD6;CYP4A11;CYP20A1;ALOX12B
monooxygenase activityCYP4A10;CYP20A1;YWHAE1;CYP2N13;CYP2AA1;MICAL2B;CYP4F18;CYP2D9;CYP2A12
oxidoreductase activityCYP2K17;AKR7A5;F8;GPD1;SC5D;AKR1E1;RYROXD1;CYP2D10;PYROXD1
oxygen bindingHBBE2;CYP1A4;HBB-B2;CYP2AA8;FAM84B;CYP2R1;CYP2AA9;CYP2F2;HBAA
quinine 3-monooxygenase activityCYP3A4;FAM84B
steroid bindingSERPINA6;ESR2A;AKR1D1;HSD17B10;NR3C2;ESRRGA;ESR1;PGR;PAQR5A
steroid hydroxylase activityCYP2AD3;CYP21A2;CYP2AA8;CYP46A1.2;CYP2AA12;CYP2AA3;CYP2C55;CYP2X9;CYP2P10
taurochenodeoxycholate 6alpha-hydroxylase activityFAM84B;CYP3A4
testosterone 6-beta-hydroxylase activityCYP3A25;CYP3A4;CYP3A41A;CYP3A41B;FAM84B
vitamin D 24-hydroxylase activityCYP1A1;FAM84B;CYP3A4
vitamin D3 25-hydroxylase activityFAM84B;CYP2R1;CYP3A4;CYP27A1

FAM84B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM84B here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM84B.

UROD; CHEK2; RAD51; XRCC3; BAG4; PTPN1; FGFR4; NOTCH2; SMAD4; PALB2; ESR2

Du, MJ; Yuan, TZ; et al. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. HUMAN MOLECULAR GENETICS 24:154-166(2015).
Ji, W; Bian, ZH; et al. Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. INTERNATIONAL JOURNAL OF CANCER 134:1279-1288(2014).
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