FAM84B
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Official Full Name
family with sequence similarity 84, member B -
Overview
FAM84B belongs to the FAM84 family. It is expressed in esophageal squamous cell carcinomas. -
Synonyms
FAM84B;family with sequence similarity 84, member B;protein FAM84B;BCMP101;breast cancer membrane associated protein 101;neurological/sensory 2;NSE2;BF642811;D330050I23Rik;Breast cancer membrane protein 101;Breast cancer membrane-associated protein 101;FA84B_HUMAN;Family with sequence similarity 84 member B;OTTHUMP00000228215;Protein NSE2;RGD1562236
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FAM84B-12729H | Recombinant Human FAM84B, His-tagged | E.coli | Human | His | 1-310a.a. | |
| FAM84B-2442H | Recombinant human FAM84B, His-tagged | E.coli | Human | His |
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| FAM84B-3809H | Recombinant Human FAM84B Protein, GST-tagged | Wheat Germ | Human | GST |
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| FAM84B-3992Z | Recombinant Zebrafish FAM84B | Mammalian Cells | Zebrafish | His |
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| FAM84B-6342HCL | Recombinant Human FAM84B 293 Cell Lysate | HEK293 | Human | Non |
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| FAM84B-4648HF | Recombinant Full Length Human FAM84B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 310 amino acids |
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Involved Pathway
FAM84B involved in several pathways and played different roles in them. We selected most pathways FAM84B participated on our site, such as Aflatoxin B1 metabolism,Aflatoxin activation and detoxification,Benzo(a)pyrene metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM84B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chemical carcinogenesis | HSD11B1,SULT1A4,ADH6,AKR1C2,CYP3A41A,UGT2A3,UGT1A6A,MGST2,GSTM6,MGST3 |
| Cytochrome P450 - arranged by substrate type | FDX1L,CYP2AD6,CYP51A1,CYP2K17,CYP2V1,CYP11B2,CYP1A1,CYP2K8,POMCB,CYP2AD3 |
| Benzo(a)pyrene metabolism | AKR1A1,AKR1C2,CYP1B1,CYP3A4,CYP1A1,AKR1C4 |
| Aflatoxin activation and detoxification | DPEP2,GGT6,CYP3C4,CYP2Y3,CYP3A5,GGTLC1,PRKRA,CYP3A4,CYP2A13,ACY3.2 |
| Bile secretion | SLC9A3,Adcy4,ATP1B3,SLC10A2,SLC5A1,Abcb1b,OSTB,ADCY3,NR1H4,ADCY8 |
| Aflatoxin B1 metabolism | CYP1A2,PRKRA,CYP2A13,CYP3A4 |
| Biological oxidations | CYP3C1,CYP27B1,SLC35B2,AHCY,PRKRA,UGT1B2,POMCB,CYP3C4,FDX1L,CYP2AD2 |
Protein Function
FAM84B has several biochemical functions, for example, aromatase activity,caffeine oxidase activity,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM84B itself. We selected most functions FAM84B had, and list some proteins which have the same functions with FAM84B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heme binding | IDO1,CYBA,BA1,CYP17A2,HBBE3,CYP2J6,HBB-Y,CBSA,CYP2C50,CYP4V2 |
| aromatase activity | CYP3A25,CYP1A1,CYP2C9,CYP2J6,CYP4A12A,CYP1B1,CYP2F1,CYP4Z1,CYP2J2,CYP4B1 |
| iron ion binding | ALOX8,CYP39A1,CYP4B1,JHDM1D,CYP11A1,CYP2U1,P4HA1A,PPEF1,CYP2N13,CYP2X9 |
| oxygen binding | CYP2K17,CYP2X7,CYP3A4,CYP2D26,CYP2A13,CYP1B1,CYP2C70,CYP4B1,CYP2K19,CYP2J6 |
| vitamin D3 25-hydroxylase activity | CYP3A4,CYP2R1,CYP27A1 |
| quinine 3-monooxygenase activity | CYP3A4 |
| caffeine oxidase activity | CYP2C39,CYP1A2,CYP2C9,CYP2C38,CYP3A4 |
| testosterone 6-beta-hydroxylase activity | CYP3A25,CYP3A41A,CYP3A4,CYP3A41B |
| vitamin D 24-hydroxylase activity | CYP1A1,CYP3A4 |
Interacting Protein
FAM84B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM84B here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM84B.
UROD;CHEK2;RAD51;XRCC3;BAG4;PTPN1;FGFR4;NOTCH2;SMAD4;PALB2;ESR2
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References
- Du, MJ; Yuan, TZ; et al. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. HUMAN MOLECULAR GENETICS 24:154-166(2015).
- Ji, W; Bian, ZH; et al. Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. INTERNATIONAL JOURNAL OF CANCER 134:1279-1288(2014).
