FBXO17 Protein, F-box protein 17

FBXO17

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FBXO17

Official Full Name F-box protein 17
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms
Synonyms FBXO17; F-box only protein 17; F-box protein FBG4; F-box only protein 26; F-box protein 17; FBXO26; FBG4; FLJ58300; FBX17; FLJ25205; FLJ11798; FBX26
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FBXO17-12786H Recombinant Human FBXO17, His-tagged E.coli His
    Human FBXO17-3917H Recombinant Human FBXO17 Protein, GST-tagged Wheat Germ GST
    Human FBXO17-6307HCL Recombinant Human FBXO17 293 Cell Lysate HEK293 N/A
    Rat FBXO17-2289R Recombinant Rat FBXO17 Protein Mammalian Cell His

    FBXO17 involved in several pathways and played different roles in them. We selected most pathways FBXO17 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System LILRB4; KLC3; NA; MAPKAP1; ASB13; UBE2V2; CLEC2B; UBR2; PJA1; NCR3LG1
    Antigen processing: Ubiquitination &amp RNF220; TRIM63; UBR1; UBE2F; ASB9; UBE2E3; SPSB4; FBXO27; ASB11; WWP1
    Proteasome degradation TRIM41; RNF14; RNF41; TRIM63; ASB6; ASB17; RNF34; FBXO27; RNF138; ASB3
    Class I MHC mediated antigen processing &amp VPRBP; MKRN1; LRR1; CMTM2A; UBE2V1; ASB3; ERAP2; STUB1; GAN; SEC24A
    presentation LRRC41; WWP1; RNF182; RNF19B; FCGR1B; PJA1; UBE2V2; RNF144B; SPSB4; TPP2
    Immune System RNF220; CYBB; CD207; IRF6; TRIM5; CXADR; ICAM4; KPNA4; IRF4; RIPK3
    Selenium Metabolism and Selenoproteins SELK; SELENBP1; TXNRD3IT1; CREM; FBXO17; TRNAU1AP; DIO2; SELT; TXNRD2; MSRB1

    FBXO17 has several biochemical functions, for example, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO17 itself. We selected most functions FBXO17 had, and list some proteins which have the same functions with FBXO17. You can find most of the proteins on our site.

    Function Related Protein
    glycoprotein binding FBXO17; PTBP3; BMPR1B; TGFB1; Shh; FLNA; STX1A; APOH; VWF; SDC1
    protein binding LBP; PCDH18B; ATG7; LSM11; DBNL; PML; UPK3A; MAST2; cgr2b; CD8A

    FBXO17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO17 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO17.

    SKP1; COPS6; COPS5

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