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Official Full Name gamma-glutamyltransferase 6
Background GGT6 belongs to the gamma-glutamyltransferase (GGT; EC gene family. GGT is a membrane-bound extracellular;enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl;moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione;synthesis (Heisterkamp et al., 2008 (PubMed 18357469)).
Synonyms GGT6; gamma-glutamyltransferase 6; gamma glutamyltransferase 6 homolog (rat); FLJ90165; Gamma glutamyltranspeptidase 6; GGT 6; gamma-glutamyltranspeptidase 6; gamma-glutamyltransferase 6 homolog
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GGT6-4878H Recombinant Human GGT6 Protein, GST-tagged Wheat Germ GST
    Human GGT6-701HCL Recombinant Human GGT6 cell lysate N/A
    Mouse GGT6-6333M Recombinant Mouse GGT6 Protein Mammalian Cell His
    Rat GGT6-2524R Recombinant Rat GGT6 Protein Mammalian Cell His

    GGT6 involved in several pathways and played different roles in them. We selected most pathways GGT6 participated on our site, such as Aflatoxin activation and detoxification, Biological oxidations, Cyanoamino acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aflatoxin activation and detoxification ACY3.1; PRKRA; GGT6; CYP3C1; CYP3A5; ACY3.2; CYP1A2; FAM84B; DPEP2; CYP2Y3
    Biological oxidations CYP3A7; PAOX; SULT1C4; CYP2J2; SLC35B2; CYP2U1; CYP19A1; CYP7A1; CYP11B1; CYP4F22
    Cyanoamino acid metabolism GGT1; GGT5A; GGT6; GBA3; GGT1A; SHMT1; GGT7; SHMT2; GGT5
    Glutathione conjugation GSTO2; GGT6; GSTK1; AKR1A1; GGTLC1
    Glutathione metabolism MGST3; ODC1; SRM; GGT5; GSTP1; RRM1; GSTT2; GSTAL; GGCTB; GSTT1B
    Glutathione synthesis and recycling GGT6; GGTLC1
    Metabolic pathways PFKMA; GOT2; R05D11.9; IMPDH2; ALPI.1; UCKL1; AADAT; NDUFB8; DAO; LASS2
    Metabolism PTPMT1; AKR1B15; SPTLC1; CSNK1G2; ANKRD1; ACOT9; FA2H; AZIN1A; ACY3; SLC25A15B

    GGT6 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT6 itself. We selected most functions GGT6 had, and list some proteins which have the same functions with GGT6. You can find most of the proteins on our site.

    Function Related Protein
    gamma-glutamyltransferase activity GGT1A; GGT7; GGTLC1; GGT5; GGT1; GGT6; GGT5A
    glutathione hydrolase activity GGT1; GGT7; GGT6; GGT5

    GGT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT6.


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