ggt7
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  • Official Full Name
  • gamma-glutamyltransferase 7
  • Background
  • This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.
  • Synonyms
  • GGT7; gamma-glutamyltransferase 7; gamma glutamyltransferase like 3 , GGTL3, GGTL5; D20S101; dJ18C9.2; GGT 7; glutathione hydrolase 7; gamma-glutamyltransferase 4; gamma-glutamyltranspeptidase 7; gamma-glutamyltransferase-like 3; gamma-glutamyltransferase
Cat.#:GGT7-6334MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GGT7 Protein
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Cat.#:GGT7-2525RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GGT7 Protein
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Cat.#:GGT7-1841RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GGT7 Protein, His-tagged
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Involved Pathway

GGT7 involved in several pathways and played different roles in them. We selected most pathways GGT7 participated on our site, such as Taurine and hypotaurine metabolism, Cyanoamino acid metabolism, Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Taurine and hypotaurine metabolism
GAD1B; GGT1A; GGT5; CDO1; ADO; ADOB; GGT7; GAD1; GGT5A; GAD2
Cyanoamino acid metabolism
SHMT1; GGT1; GGT7; GGT5; GGT1A; SHMT2; GBA3; GGT6; GGT5A
Glutathione metabolism
G6PDX; SRM; GSTA2; MGST3; LAP3; GPX1; GSTM4; GGT7; GSTT2B; MGST1.1
Metabolic pathways
PDHA1B; NDST3; RFK; EHHADH; PIP5KL1; EXT1; RPE; GRHPRA; PLCG2; MOCS2

Protein Function

GGT7 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT7 itself. We selected most functions GGT7 had, and list some proteins which have the same functions with GGT7. You can find most of the proteins on our site.
Function
Related Protein
Function gamma-glutamyltransferase activity
Related Protein GGT1; GGT6; GGT5A; GGTLC1; GGT5; GGT1A; GGT7
Function glutathione hydrolase activity
Related Protein GGT7; GGT1; GGT6; GGT5
Function hydrolase activity
Related Protein MMP25; MEST; ENPP5; METAP2; DUB1; FAM108A; GM5136; HDAC7; ABHD14B; SIRT3
Function molecular_function
Related Protein VMN1R148; PTGES3L; Defa17; C8orf42; WDR7; CFDP1; SETD5; REEP3B; Mamdc4; TMEM30AA
Function transferase activity
Related Protein METTL21D; CAMK2N1A; UGT2B6; GGT7; SETD8A; GRK7B; KAT7B; DNMT5; ST3GAL5L; COQ2
Function transferase activity, transferring acyl groups
Related Protein ZDHHC20A; GLYAT; DGAT1; ZDHHC21; ZDHHC15B; TMEM68; ZDHHC23B; AANAT; NMT1A; HHAT

Interacting Protein

GGT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT7.
Ywhae

GGT7 Related Articles

Ruhl, CE; Menke, A; et al. Relationship of Hepatitis C Virus Infection With Diabetes in the US Population. HEPATOLOGY 60:1139-1149(2014).
Schmidt, CS; Schon, D; et al. Viral Hepatitis in Alcohol-Dependent Inpatients Prevalence, Risk Factors, and Treatment Uptake. JOURNAL OF ADDICTION MEDICINE 7:417-421(2013).