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GNAT1

Official Full Name

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Overview

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms

GNAT1; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; guanine nucleotide-binding protein G(t) subunit alpha-1; GBT1; GNATR; guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1; guanine nucleotide binding protein G(T) alpha 1 subunit; Rod specific transducin; OTTHUMP00000210665; OTTHUMP00000210666; transducin alpha-1 chain; transducin, rod-specific; rod-type transducin alpha subunit; guanine nucleotide-binding protein G(T), alpha-1 subunit; CSNBAD3;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	GNAT1-803H	Recombinant Human GNAT1 Protein, His-tagged	E.coli	His	Inquiry
Mouse	GNAT1-7021M	Recombinant Mouse GNAT1 Protein	Mammalian Cell	His	Inquiry
Mouse	GNAT1-3763M	Recombinant Mouse GNAT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	GNAT1-3763M-B	Recombinant Mouse GNAT1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	GNAT1-9372Z	Recombinant Zebrafish GNAT1	Mammalian Cell	His	Inquiry
Chicken	GNAT1-6257C	Recombinant Chicken GNAT1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

GNAT1 involved in several pathways and played different roles in them. We selected most pathways GNAT1 participated on our site, such as Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Phototransduction	CALML5;OPN1MW4;GRK1A;GNB1A;RGS9A;GNAT1;RLN1;GUCA1B;CALM3

GNAT1 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAT1 itself. We selected most functions GNAT1 had, and list some proteins which have the same functions with GNAT1. You can find most of the proteins on our site.

Function	Related Protein
G-protein beta/gamma-subunit complex binding	GNAT3;GNA12;GNA13A;GNA15;GNAI1;GNA14;GNA13B;GNAO1B;ADORA1
GTP binding	RAB35B;EEF1A1L1;ARL8A;RAB28;GNAQ;RAB27B;ATL3;GNL3;RAB39BB
GTPase activity	RRAGCB;ARFRP1;GPN1;RAB22A;ARHGAP5;GNAL;RAB43;RRAS2;EIF5B
guanyl nucleotide binding	GNA12A;GNAIA;GNA11A;GNAO1B;GNA11B;GNAI2B;GNAI2A;GNA15.4;GNAT1
metal ion binding	FHL1A;ZFP553;KDM5BB;TRIM35-21;CALUA;ZFP28;PRDM16;ARIH1L;EGLN1B
nucleotide binding	SRSF10;RBM4;MAP2K4B;ESRP1;MYH11A;PKN1B;RBMY1F;RBM46;TINAG
protein binding	RAD9;ZNF16;PEX26;ALX1;MYRIP;PRCC;DPYSL3;GJD3;CEP152

GNAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAT1.