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H2-Aa

Official Full Name

histocompatibility 2, class II antigen A, alpha
Synonyms

H2-AA;histocompatibility 2, class II antigen A, alpha;ENSMUSG00000036594;Ia1;H2Aa;Ia-1;H-2Aa;Aalpha;IAalpha;I-Aalpha;17 B1;17 18.65 cM;histocompatibility 2, class II antigen A, alpha;histocompatibility 2, class II antigen A, alpha;A alpha;MHC-II I-A(d) alpha;MHC class II antigen;major histocompatibility protein class II alpha chain;H-2 class II histocompatibility antigen, A-B alpha chain;H-2 class II histocompatibility antigen, A-F alpha chain;H-2 class II histocompatibility antigen, A-K alpha chain;H-2 class II histocompatibility antigen, A-Q alpha chain;H-2 class II histocompatibility antigen, A-R alpha chain;H-2 class II histocompatibility antigen, A-S alpha chain;H-2 class II histocompatibility antigen, A-U alpha chain;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	H2-AA-7424M	Recombinant Mouse H2-AA Protein	Mammalian Cell	His	Inquiry
Mouse	H2-Aa-1084M	Recombinant Mouse H2-Aa Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Mouse	H2-AA-4038M	Recombinant Mouse H2-AA Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	H2-AA-4038M-B	Recombinant Mouse H2-AA Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
H2-Aa Related Articles

H2-Aa involved in several pathways and played different roles in them. We selected most pathways H2-Aa participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-Aa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Phagosome	ATP6V0CA;ATP6V0E2;CD36;ATP6V1H;TLR4BA;Ctsl;TUBB2B;DYNC1I2A;CTSL1B
Cell adhesion molecules (CAMs)	NLGN2B;CLDN10A;NLGN1;CLDN11A;CADM1A;HLA-DRB5;NLGN2A;CLDN14;ICAM1
Antigen processing and presentation	KIR3DL2;HLA-C;HLA-E;KIR2DL3;KLRC2;KIR2DL4;HLA-DPA1;HLA-DPB1;HLA-B
Intestinal i	ICOSLG;Il2;HLA-DRB3;HLA-DRA;HLA-DOB;CD40LG;BLB2;HLA-DOA;CD80
ne network for IgA production	IL6;HLA-DMB;CCL25;CD28;CCL27B;ICOS;ITGA4;H2-AA;CD40LG
Type I diabetes mellitus	IL1B;H2-AA;CD28;HLA-DRB5;HLA-DMB;PTPRN;HLA-F;HLA-A;Fasl
Leishmaniasis	FCGR1;HLA-DOA;FCGR4;ITGB2L;PTGS2;NCF2;NFKBIA;IFNGR2;TAB2
Toxoplasmosis	NFKBIA;GNAI2;IRGM;LAMB2;LAMA3;IKBKB;H2-AB1;RELA;MAPK12
Staphylococcus aureus infection	HLA-DPA1;DSG1C;PLG;C5AR1;HLA-DQA2;C1QC;CFB;FPR1;HLA-DRB5
Tuberculosis	cgr2b;FCGR2A;CARD9;PPP3CB;ATP6V0D1;TRAF6;STAT1;CALM1;HSPA9
Influenza A	HLA-DQA2;IFNGR1;MAP2K7;NXF3;PYCARD;KPNA1;RNASEL;MAP2K2;IFNAR1
HTLV-I infection	Il2;LTA;TGFBR2;RRAS2;WNT5B;DVL3;ZFP36;ELK1;POLD1
Herpes simplex infection	IL12A;IKBKE;IL12BA;PKZ;PPP1CB;TAF3;IFNA5;EIF2AK3;IFNGR2
Asthma	FCER1G;HLA-DPA1;CD40;HLA-DRA;IL13;HLA-DRB4;HLA-DQB1;HLA-DQA1;HLA-DMA
Autoi	IFNA7;CD86;CD40;HLA-DRB5;IFNA17;FASLG;TSHR;IFNA14;H2-AA
ne thyroid disease	Ifna11;IFNA16;CD80;FAS;HLA-DQA1;Fasl;HLA-DRB1;IFNA13;HLA-DPA1
Inflammatory bowel disease (IBD)	TGFB2;STAT4;Il2;HLA-DQB1;IL23;IL12RB1;IL17A;HLA-DQA1;IL18RAP
Systemic lupus erythematosus	HIST1H3F;HIST1H3I;HIST1H2BF;HIST1H2AF;HLA-DQB1;C1QB;HIST2H2AA4;HLA-DPB1;TNF
Rheumatoid arthritis	ANGPT1;HLA-DQB1;IL11;CCL3;MMP1;ATP6V0B;TGFB1;IL17A;HLA-DRA
Allograft rejection	HLA-DQA1;H2-AB1;HLA-G;HLA-B;HLA-C;Fasl;HLA-DOA;IL12B;HLA-DOB
Graft-versus-host disease	Fasl;FAS;H2-Q10;H2-AA;IL6;HLA-C;HLA-DRA;KIR3DL2;CD28
Viral myocarditis	CXADR;CYCS;HLA-F;SGCB;H2-Q10;CASP8;CD28;CD86;ICAM1

H2-Aa has several biochemical functions, for example, peptide antigen binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2-Aa itself. We selected most functions H2-Aa had, and list some proteins which have the same functions with H2-Aa. You can find most of the proteins on our site.

Function	Related Protein
peptide antigen binding	HLA-DRB5;DHCR24;HLA-DPB1;H2-AA;MHC1UBA;MHC1ZDA;TAPBP;MHC1UIA;TAP1
protein binding	STK10;LRP12;NCOA2;EEF1A1;USP33;MPZL1L;STK38L;TAF15;KIAA1958
protein heterodimerization activity	MCL1;BCL2A;HIST1H2AF;KHDRBS2;HIST1H2BF;LIMK2;BAXB;PPP1CBL;NFYBB

H2-Aa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-Aa here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-Aa.

H2-Ab1

Zemelka-Wiacek, M; Szczepanik, M; et al. Tc1-mediated contact sensitivity reaction, its mechanism and regulation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 68:955-969(2014).

Schwaiger, J; Aberle, JH; et al. Specificities of Human CD4(+) T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction. JOURNAL OF VIROLOGY 88:7828-7842(2014).