H2-Aa Protein, histocompatibility 2, class II antigen A, alpha


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Official Full Name histocompatibility 2, class II antigen A, alpha
Synonyms H2-AA;histocompatibility 2, class II antigen A, alpha;ENSMUSG00000036594;Ia1;H2Aa;Ia-1;H-2Aa;Aalpha;IAalpha;I-Aalpha;17 B1;17 18.65 cM;histocompatibility 2, class II antigen A, alpha;histocompatibility 2, class II antigen A, alpha;A alpha;MHC-II I-A(d) alpha;MHC class II antigen;major histocompatibility protein class II alpha chain;H-2 class II histocompatibility antigen, A-B alpha chain;H-2 class II histocompatibility antigen, A-F alpha chain;H-2 class II histocompatibility antigen, A-K alpha chain;H-2 class II histocompatibility antigen, A-Q alpha chain;H-2 class II histocompatibility antigen, A-R alpha chain;H-2 class II histocompatibility antigen, A-S alpha chain;H-2 class II histocompatibility antigen, A-U alpha chain;
    • Species :
    • Mouse
    • Source :
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse H2-Aa-1084M Recombinant Mouse H2-Aa Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse H2-AA-7424M Recombinant Mouse H2-AA Protein Mammalian Cell His

    H2-Aa involved in several pathways and played different roles in them. We selected most pathways H2-Aa participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-Aa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) CLDN15LA; HLA-DPA1; NCAM1A; Ntng2; CLDN19; ITGAV; CLDNE; OCLNB; CD2; LRRC4
    Antigen processing and presentation CANX; HLA-DRA; CTSS; HLA-DQA1; KIR2DL3; HLA-G; HLA-A; HSPA1B; KLRC4; H2-AB1
    Intestinal i CD40; HLA-DQA1; BMA1; HLA-DRB4; HLA-DPA1; HLA-DRA; CXCR4B; TNFRSF13B; BLA; CD86
    ne network for IgA production HLA-DMB; TGFB1A; HLA-DPA1; HLA-DPB1; BLB2; HLA-DRA; TNFSF13; HLA-DOA; IL4; TNFRSF13B
    Type I diabetes mellitus HLA-DQA2; IL1A; HLA-DRB1; HLA-F; HLA-C; PTPRN2; GAD1; CPE; IL12B; HLA-DMB
    Leishmaniasis Itgam&Itgb2; TGFB2; MAPK3; FCGR3B; HLA-DRA; IRAK1; STAT1; FCGR4; FCGR2A; HLA-DRB5
    Toxoplasmosis Casp3; BIRC8; NFKB1; IL10RA; GNAI1; BCL2; TLR2; LAMC2; PIK3CG; LAMB1
    Staphylococcus aureus infection C1R; MASP1; MBL1; MBL2; HLA-DMB; GM5077; FCGR3A; FCGR3B; ICAM1; C3AR1
    Tuberculosis Casp3; Ifna15; CLEC4E; ATP6V0D2; CD209A; Pla2r1; NFYC; IFNB1; IFNA5; TNFRSF1A
    Influenza A EP300; IRAK4; DNAJB1; RNASEL; IL33; STAT1; LOC100686744; HLA-DRA; IFNA6; MAPK8
    HTLV-I infection H2-AB1; RANBP1; NFKB2; PPP3R1; PPP3R2; MAP2K4; ITGB2L; VDAC2; TP53INP1; ITGAL
    Herpes simplex infection TNF; Casp3; EIF2AK2; IRF9; SRSF5B; Fasl; C3A.1; HLA-E; NXF2; EP300
    Asthma EPX; IL5; FCER1A; CD40LG; PRG2; IL4; HLA-DRB4; H2-AB1; FCER1G; CD40
    Autoi IL4; PRF1; IL5; H2-Q10; TSHR; HLA-C; CD28; Ifna15; H2-AB1; HLA-DQA2
    ne thyroid disease HLA-DMA; CD80; H2-AA; CD40; IFNA21; HLA-F; TSHR; Fasl; PRF1; CD40LG
    Inflammatory bowel disease (IBD) HLA-DMB; HLA-DRB5; HLA-DRB4; TGFB3; TBX21; STAT6; TGFB2; IL22; IL12B; GATA3
    Systemic lupus erythematosus HIST1H2AN; HIST1H2AJ; HIST1H2AE; H2AFV; HIST2H2AA2; GRIN2A; CD86; C2; HLA-DQB1; FCGR2A
    Rheumatoid arthritis CD86; HLA-DPB1; ATP6V1B2; ATP6V1C1; FOS; HLA-DMA; TLR2; HLA-DRB4; ATP6V0C; CXCL5
    Allograft rejection TNF; HLA-DMB; H2-AB1; H2-Q10; Il2; IFNG; Fasl; HLA-DMA; HLA-DQB1; HLA-B
    Graft-versus-host disease HLA-DQB1; HLA-DMB; IL1A; PRF1; HLA-A; HLA-DRA; KLRD1; H2-Q10; HLA-C; KIR2DL1
    Viral myocarditis HLA-DPA1; RAC2; CD40; ABL2; CCND1; HLA-DQA2; RAC1; HLA-A; CAV1; HLA-DMB

    H2-Aa has several biochemical functions, for example, peptide antigen binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2-Aa itself. We selected most functions H2-Aa had, and list some proteins which have the same functions with H2-Aa. You can find most of the proteins on our site.

    Function Related Protein
    peptide antigen binding HLA-DRA; MHC1ZFA; MHC1UBA; DHCR24; CD209; MAML1; MHC1UXA2; HLA-G; MHC1UJA; HLA-DQA1
    protein binding SH3RF1; ACVR1B; TCF7L1A; REEP5; NOTCH2; LCE1B; BATF; GRIN2C; ITGA7; ARHGAP1
    protein heterodimerization activity ADRA2A; H2AFZ; SNX5; HIST1H4C; ZHX1; MAFGA; HEXA; PPP1CBL; TAF8; HIST1H2BH

    H2-Aa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-Aa here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-Aa.


    Zemelka-Wiacek, M; Szczepanik, M; et al. Tc1-mediated contact sensitivity reaction, its mechanism and regulation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 68:955-969(2014).
    Schwaiger, J; Aberle, JH; et al. Specificities of Human CD4(+) T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction. JOURNAL OF VIROLOGY 88:7828-7842(2014).

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