|Official Full Name||homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1|
|Background||The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]|
|Synonyms||HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; SUP; HERP; Mif1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; MMS-inducible; methyl methanesulfonate (MMF)-inducible fragment protein 1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
HERPUD1 involved in several pathways and played different roles in them. We selected most pathways HERPUD1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with HERPUD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Protein processing in endoplasmic reticulum||PRKCSH; UBE2D4; MAP2K7; DNAJB12A; CAPN1; UBQLNL; CRYABA; ATXN3L; ATF4B1; DNAJC5G|
HERPUD1 has several biochemical functions, for example, ion channel binding, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HERPUD1 itself. We selected most functions HERPUD1 had, and list some proteins which have the same functions with HERPUD1. You can find most of the proteins on our site.
|ion channel binding||YWHAQ; FGF13; GPD1L; HERPUD1; KCNB2; FKBP1A; FXYD1; KCNQ1; SNTA1; CIB1|
|molecular_function||TDEANC2; SPECC1LA; DSCR10; SERHL2; KRTAP5-1; POPDC2; FAM117AB; OBSL1; SPRY3; TMEM144A|
|protein binding||PPP1R37; KRT6B; POU5F1; CSF1; ALKBH3; SAFB2; HTATIP2; UBE2D2A; LIPT2; KRT15|
HERPUD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HERPUD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HERPUD1.
UBXN6; IMPA2; XRCC6; RPA2; CD58; ARHGDIA; EWSR1; USP7; TOLLIP; STARD9