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MCM4

  • Official Full Name

    minichromosome maintenance complex component 4

  • Overview

    The MCM4 protein (minichromosome maintenance protein 4) is a nuclear 100 kD DNA-dependent ATPase. The MCM4 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM4 togethe
  • Synonyms

    MCM4; minichromosome maintenance complex component 4; CDC21, MCM4 minichromosome maintenance deficient 4 (S. cerevisiae); DNA replication licensing factor MCM4; CDC54; hCdc21; MGC33310; P1 Cdc21; CDC21 homolog; minichromosome maintenance deficient 4; hom;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MCM4-28040TH Recombinant Human MCM4, His-tagged E.coli His
Human MCM4-4418HCL Recombinant Human MCM4 293 Cell Lysate HEK293 N/A
Human MCM4-1876H Recombinant Human MCM4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MCM4-3275H Recombinant Human MCM4 protein, His-tagged E.coli His 515-859 aa
Human MCM4-1384H Recombinant Human MCM4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse MCM4-9637M Recombinant Mouse MCM4 Protein Mammalian Cell His
Mouse MCM4-5413M-B Recombinant Mouse MCM4 Protein Pre-coupled Magnetic Beads HEK293
Mouse MCM4-5413M Recombinant Mouse MCM4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MCM4-2704R Recombinant Rhesus monkey MCM4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MCM4-2524R-B Recombinant Rhesus Macaque MCM4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MCM4-2524R Recombinant Rhesus Macaque MCM4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish MCM4-9873Z Recombinant Zebrafish MCM4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MCM4 Related Articles

MCM4 involved in several pathways and played different roles in them. We selected most pathways MCM4 participated on our site, such as DNA replication, Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA replicationRNASEH1;CDT1;MCM6;RFC1;RFC4;RPA2;rnhA;POLE;MCM10
Cell cycleSTAG2;CDK7;MCM9;SMC3;TTK;SYCP2;TFDP1A;MAPRE1;RBX1

MCM4 has several biochemical functions, for example, ATP binding, contributes_to ATP-dependent DNA helicase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM4 itself. We selected most functions MCM4 had, and list some proteins which have the same functions with MCM4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingACSS3;MYO1C;CKMB;PKN2;SNRKB;CSNK1E;CHD1L;ABCD4;DARS
contributes_to ATP-dependent DNA helicase activityMCM7;NBN;MCM6;MCM4;MRE11A;RAD50
protein bindingARHGAP4;ANKRA2;EWSR1;IL11;PSME3;SYNGR1;OPA1;PKN1;LSM4
single-stranded DNA bindingHNRPDL;TDP1;CNBP;HNRNPK;NCL;TSNAX;ANXA1;PEO1;RAD51D

MCM4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM4.

MCM7; MCMBP

Gan, N; Du, Y; et al. Increase of Mcm3 and Mcm4 expression in cervical squamous cell carcinomas. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 31:291-294(2010).
Gambichler, T; Shtern, M; et al. Minichromosome maintenance proteins are useful adjuncts to differentiate between benign and malignant melanocytic skin lesions. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 60:808-813(2009).
  • Q&As
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