IFNA3
-
Official Full Name
interferon alpha 3 -
Overview
Human type I interferons comprise a vast and growing group of IFN proteins. All type I IFNs bind to a specific cell surface re-ceptor complex known as the IFN-alpha receptor (IFNAR) that con-sists of IFNAR1 and IFNAR2 chains. Homologous molecules to type -
Synonyms
IFNA;IFNA1;IFNA2;IFNA6;IFN-alpha;IFN-gamma;interferon type A1/A2;Interferon-alpha;IFN-alpha;IFNAR;Pegylated interferon alfa-2a;Pegylated interferon alfa-2b;IFN-alphaA;MGC125764;MGC125765;IFNA8;IFNA10;IFNA14;IFNA17;Pegylated interferon al-fa-2b;IFNA2;Pegylated interferon alfa-2b
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFNA-117C | Recombinant Chicken Interferon Alpha | Yeast | Chicken | Non |
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| IFNA3-129C | Recombinant Chicken Interferon | E.coli | Chicken | Non |
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| IFNA3-6978C | Recombinant Chicken IFNA3 | Mammalian Cells | Chicken | His |
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Involved Pathway
IFNA3 involved in several pathways and played different roles in them. We selected most pathways IFNA3 participated on our site, such as Cytokine-cytokine receptor interaction,Regulation of autophagy,Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Toll-like receptor signaling pathway | CD86,AKT2L,MAPK12,MAPK9,MAPK14A,TICAM2,IL12A,MAPK14B,IFNA8,CASP8 |
| Jak-STAT signaling pathway | Il23a,PRLR,IL-15RA,NT5C3,STAT4,IFNAR2,GFAP,PTPN6,IL10RB,SOS1 |
| Influenza A | MAPK8,HLA-DRB3,HSPA2,AKT1,VDAC1,PYCARD,IFNA21,Ifna15,HLA-DQA1,DNAJB1 |
| Cytokine-cytokine receptor interaction | FIGF,Ccl27a,IL11,CCR1L1,LTA,IFNA1,FLT1,CSF3R,TNFRSF13C,TNFB |
| Herpes simplex infection | SRSF2B,TLR2,TLR3,FAS,SRSF5A,HLA-DQB1,RNASEL,FADD,IFNA5,IFIT1 |
| Regulation of autophagy | IFNA6,IFNA14,IFNA7,IFNA12,IFNG,IFNPHI1,IFNA17,IFNA5,IFNA16,ATG10 |
| Cytosolic DNA-sensing pathway | IRF3,TREX1,POLR2L,IFNA2,IFNA4,RIPK1,CXCL10,CCL5,IFNPHI1,NFKBIB |
| RIG-I-like receptor signaling pathway | DDX3X,NFKBIAB,IKBKB,DHX58,MAPK8B,FADD,NFKBIA,IFNA4,NFKB1,NFKBIAA |
Protein Function
IFNA3 has several biochemical functions, for example, cytokine activity,cytokine receptor binding,type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA3 itself. We selected most functions IFNA3 had, and list some proteins which have the same functions with IFNA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IFNPHI2,TNFSF9,THPO,IL25,TIMP1,AIMP1,Il1f6,TNFSF13,KITLG,GDF6B |
| cytokine receptor binding | IL17C,IFNW1,IL15,IFNA8,IL21,IFNA13,IL15L,IFN-a,IFNA5,IFNA14 |
| type I interferon receptor binding | Ifnz,IFNA2,IFNB1,IFNE,IFNA10,IFNPHI1,IFNPHI4,IFNPHI2,GM13279,IFNA14 |
Interacting Protein
IFNA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA3.
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