ifna4
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  • Official Full Name
  • interferon, alpha 4
  • Background
  • Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by a wide variety of cells types in response to challenges by foreign agents such as viruses, parasites and tumor cells.
  • Synonyms
  • IFNA4; interferon, alpha 4; interferon alpha-4; IFN alpha4a; MGC142200; Interferon alpha 4 precursor; Interferon alpha 4B; Interferon alpha 76; Interferon alpha M1; IFN-alpha-4; interferon alpha-4B; interferon alpha-76; interferon alpha-M1; INFA4; IFN-alpha4a
Cat.#:IFNA4-432HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-1190HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, MYC/DDK-tagged
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Cat.#:IFNA4-75HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 4
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Cat.#:IFNA4-156HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-175HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4, His tagged
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Cat.#:IFNA4-193HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
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Cat.#:IFNA4-29HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4, Fc tagged
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Cat.#:IFNA4-597HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4
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Cat.#:Ifna4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, Fc-tagged
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Cat.#:Ifna4-157MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ifna4 Protein, His-tagged
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Cat.#:IFNA4-183MTag:GST
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, His tagged
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Cat.#:Ifna4-596MTag:
Source (Host):mammalian cellsSpecies:Mouse
Product nameRecombinant Mouse Ifna4
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Cat.#:Ifng4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifng4 protein, Fc-tagged
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Cat.#:Ifna4-158RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ifna4 Protein, His-tagged
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Cat.#:Ifna4-7447RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ifna4, Fc tagged
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Cat.#:IFNA4-8840CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4, Fc tagged
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Cat.#:IFNA4-2933HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 cell lysate
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Cat.#:IFNA4-495HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4 cell lysate
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Cat.#:IFNA4-846MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IFNA4 cell lysate
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Cat.#:IFNA4-1412RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat IFNA4 cell lysate
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Cat.#:IFNA4-989CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4 cell lysate
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Involved Pathway

Ifna4 involved in several pathways and played different roles in them. We selected most pathways Ifna4 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ifna4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IFNGR2; IFNA21; PRLRA; CCL19B; IL21; CSF1; CRFB4; IL12RB2; IL24; CCL4L1
Regulation of autophagy
IFNA8; ATG3; IFNA5; IFNA17; IFNA21; ATG7; GABARAPL2; ATG4B; PIK3C3; ULK2
PIK-Akt signaling pathway
FGF7; GHR; LPAR2; Fasl; Itga10&Itgb1; IFNA12; PDGFD; ITGA1; IFNA8; PHLPP1
Toll-like receptor signaling pathway
TOLLIP; PIK3R5; CXCL11; IFNA8; IFNA21; RELA; AKT1; TLR5; IL12A; STAT1A
RIG-I-like receptor signaling pathway
IL8L1; RNF125; NFKBIAA; CXCL10; ATG5; MAPK8A; MAPK11; MAPK12; IFNA7; IL12B
Cytosolic DNA-sensing pathway
TBK1; POLR2E; POLR3A; IFNA16; IL18; IFNA10; IFI202B; NFKBIAA; POLR2L; IFNA8
Jak-STAT signaling pathway
IFNA4; JAK2B; SOCS5; PTPN11B; EP300; SOCS1A; IL4R; IFNK; IL6R; IFNA10
Natural killer cell mediated cytotoxicity
GRB2; IFNA17; ULBP2; FCGR3A; VAV3; PIK3R5; ARAF; VAV1; PPP3CB; FYN
Tuberculosis
FCGR1A; ATP6V0C; ITGAX; CASP8; IFNA8; IRAK4; TLR1; SPHK1; HLA-DQA1; MAPK8
Hepatitis C
MAPK1; PIK3CA; MAVS; PIK3CG; Ifna15; IFNA16; RXRA; IRF9; OAS1; IRF7
Hepatitis B
CREB5; MAPK3; BIRC5; NFATC2; IFN-a; IRF7; STAT3; PIK3CD; IFNA13; PIK3R1
Measles
IFNG; IL13; CD28; IL1B; CD209B; IFNA10; CLEC4M; CD209C; CCND3; EIF2AK4
Influenza A
HNRNPUL1; FURIN; IL6; IVNS1ABP; TRIM25; IFNGR2; HLA-DPB1; MAP2K6; IFNGR1; ICAM1
Herpes simplex infection
CUL1B; PPP1CB; BLB1; C1QBP; LTA; NXF3; MHC2A; EIF2S1B; TAF9B; CUL1
Autoi
IL5; IL4; IFNA16; HLA-G; IFNA10; TSHR; GZMB; IFNA7; CD40; Ifna15
ne thyroid disease
IFNA12; HLA-DRB5; IFNA17; HLA-DRB3; HLA-DQA1; HLA-F; HLA-DRB1; IL4; H2-AB1; FAS

Protein Function

Ifna4 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ifna4 itself. We selected most functions Ifna4 had, and list some proteins which have the same functions with Ifna4. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein TGFB3; BMP3; GDF10B; BMP5; FAM3D; IL1F10; INHBA; NAMPT; IL31; BMP7
Function protein binding
Related Protein CLDN1; SLX4IP; MSN; FCNA; CA4; BCL6; DCDC2; TAC1; ARL4C; USP28
Function type I interferon receptor binding
Related Protein RNF207B; Ifna11; IFNA6; IFNA13; GM13279; IFNK; IFNPHI3; IFNA4; Gm13290; IFNE

Interacting Protein

Ifna4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ifna4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ifna4.
ALDOA

Ifna4 Related Articles

Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
Aydinoglu-Candan, O; Araz-Ersan, B; et al. Anti-interferon alpha antibodies and autoantibodies in patients with Beh double dagger et's disease uveitis treated with recombinant human interferon alpha-2a. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 253:457-465(2015).

Ifna4 Related Gene Family

Cytokines