ifna4
Share
  • Official Full Name
  • interferon, alpha 4
  • Background
  • Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by a wide variety of cells types in response to challenges by foreign agents such as viruses, parasites and tumor cells.
  • Synonyms
  • IFNA4; interferon, alpha 4; interferon alpha-4; IFN alpha4a; MGC142200; Interferon alpha 4 precursor; Interferon alpha 4B; Interferon alpha 76; Interferon alpha M1; IFN-alpha-4; interferon alpha-4B; interferon alpha-76; interferon alpha-M1; INFA4; IFN-alpha4a
Cat.#:IFNA4-432HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
+Inquiry
Cat.#:IFNA4-1190HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:IFNA4-75HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 4
+Inquiry
Cat.#:IFNA4-156HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
+Inquiry
Cat.#:IFNA4-175HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4, His tagged
+Inquiry
Cat.#:IFNA4-193HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 Protein, His-tagged
+Inquiry
Cat.#:IFNA4-29HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4, Fc tagged
+Inquiry
Cat.#:IFNA4-597HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IFNA4
+Inquiry
Cat.#:Ifna4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, Fc-tagged
+Inquiry
Cat.#:Ifna4-157MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ifna4 Protein, His-tagged
+Inquiry
Cat.#:IFNA4-183MTag:GST
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifna4, His tagged
+Inquiry
Cat.#:Ifna4-596MTag:N/A
Source (Host):mammalian cellsSpecies:Mouse
Product nameRecombinant Mouse Ifna4
+Inquiry
Cat.#:Ifng4-122MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Ifng4 protein, Fc-tagged
+Inquiry
Cat.#:Ifna4-158RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ifna4 Protein, His-tagged
+Inquiry
Cat.#:Ifna4-7447RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ifna4, Fc tagged
+Inquiry
Cat.#:IFNA4-8840CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4, Fc tagged
+Inquiry
Cat.#:IFNA4-2933HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA4 cell lysate
+Inquiry
Cat.#:IFNA4-495HCLTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IFNA4 cell lysate
+Inquiry
Cat.#:IFNA4-846MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IFNA4 cell lysate
+Inquiry
Cat.#:IFNA4-1412RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat IFNA4 cell lysate
+Inquiry
Cat.#:IFNA4-989CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA4 cell lysate
+Inquiry

Involved Pathway

Ifna4 involved in several pathways and played different roles in them. We selected most pathways Ifna4 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ifna4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
GM13304; IL1A; Il4ra; CCL5; IFNGR1; IFNAR2; CCR6A; IL7; TSLP; PRL2
Regulation of autophagy
Ifna11; ATG4D; ATG14; ATG4A; IFNA21; GABARAPL1; Ifna15; IFNA12; GABARAP; IFNA17
PIK-Akt signaling pathway
MET; BAD; IBSP; FGF19; CREB3L2; IL6; THBS4; ITGB6; Ifna15; IL6R
Toll-like receptor signaling pathway
IFNA7; PIK3R3B; IFNA4; NFKBIAB; CD14; IFNA5; IL8L2; TLR8; TLR5B; IFNA3
RIG-I-like receptor signaling pathway
RNF125; TP-1; MAPK8B; CXCL8B.3; NFKBIA; IFNA21; RIPK1L; RELA; TANK; IFNA7
Cytosolic DNA-sensing pathway
TMEM173; POLR2EB; IRF3; OSTN; NFKBIAA; RELA; IL33; POLR3K; NFKBIA; POLR1D
Jak-STAT signaling pathway
IFNA14; PIM1; CRFB4; IFNA17; GH2; LEPA; PRL2; GM-CSF; IFNA16; AOX3L1
Natural killer cell mediated cytotoxicity
IFNA5; PIK3R5; TNF; SH2D1B; ULBP1; FCGR4; IFNA6; SH2D1A; HLA-A; MICB
Tuberculosis
CALM2; PIK3C3; IFNA10; HLA-DMA; HLA-DRB5; IFNA1; IL10RA; PPP3CC; HSPD1; IRAK1
Hepatitis C
IKBKE; OAS1A; CLDN9; IFNAR1; TRADD; PPP2CA; CLDN15; TBK1; PPP2R2D; IFNA10
Hepatitis B
SMAD3; MAPK9; IFNA21; TLR3; MAVS; IFNA4; TICAM2; TRP53; IFNA1; TGFB3
Measles
STAT5B; IRF3; PIK3R3; IFNG; PIK3R5; IFNGR1; HSPA8; STAT3; OAS1; FYN
Influenza A
KPNA1; VDAC1; BLB1; TMPRSS13; NXF1; HNRNPUL1; AKT2; IFNA8; IFNA14; IL6
Herpes simplex infection
IFNB; IFNA13; IFNB1; SRSF7A; GTF2I; HLA-DPB1; CASP3A; HLA-DRB4; SRSF2; SRSF2B
Autoi
IFNA8; HLA-F; HLA-DRB5; HLA-G; IL5; FASLG; IFNA13; HLA-DQA1; HLA-E; IFNA4
ne thyroid disease
HLA-B; HLA-DOA; H2-AB1; CD28; HLA-DQB1; HLA-DRB5; HLA-DQA2; IL5; HLA-DPB1; HLA-DRB3

Protein Function

Ifna4 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ifna4 itself. We selected most functions Ifna4 had, and list some proteins which have the same functions with Ifna4. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IL5; CER1; IFNL3; SP100; INHBAB; TGFB1A; EDN1; IL22; INHBC; IFNG1-2
Function protein binding
Related Protein PEX26; FAM164A; AMPD2; VPS41; PTTG1; CCDC28B; LCE4A; DCD; TLX3; ZDHHC17
Function type I interferon receptor binding
Related Protein GM13279; IFNK; IFNB; IFNA16; IFNPHI1; IFNA14; GM13287; IFNA12; IFNPHI4; IFNA4

Interacting Protein

Ifna4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ifna4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ifna4.
ALDOA

Ifna4 Related Articles

Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
Aydinoglu-Candan, O; Araz-Ersan, B; et al. Anti-interferon alpha antibodies and autoantibodies in patients with Beh double dagger et's disease uveitis treated with recombinant human interferon alpha-2a. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 253:457-465(2015).

Ifna4 Related Gene Family

Cytokines