Ins2
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Official Full Name
insulin 2 -
Synonyms
INS2;insulin 2;insulin-2
Recombinant Proteins
- Rat
- Mouse
- Mammalian Cells
- HEK293
- E.coli
- His
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| INS2-3077R | Recombinant Rat INS2 Protein | Mammalian Cells | Rat | His |
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| INS2-8234M | Recombinant Mouse INS2 Protein | Mammalian Cells | Mouse | His |
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| INS2-2733R | Recombinant Rat INS2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| INS2-2733R-B | Recombinant Rat INS2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Ins2-3551M | Recombinant Mouse Ins2 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| Ins2-4180M | Recombinant Mouse Ins2 protein, His&Myc-tagged | E.coli | Mouse | His&Myc | 25-110aa |
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| INS2-4561M | Recombinant Mouse INS2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| INS2-4561M-B | Recombinant Mouse INS2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Ins2 involved in several pathways and played different roles in them. We selected most pathways Ins2 participated on our site, such as Ras signaling pathway,Rap signaling pathway,cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Maturity onset diabetes of the young | FOXA3,FOXA2,MAFA,ONECUT1,BHLHA15,IAPP,NKX6,HHEX,HNF4A,HNF4G |
| Phospholipase D signaling pathway | DGKZ,PIK3CG,NRAS,Kitl,LPAR5,LPAR6,GAB2,DGKE,PDGFB,PIK3R2 |
| Insulin secretion | VAMP2,CAMK2D,GNAS,ATP1A2,CREB3L1,SLC2A2,ATP1A3,PCLO,CREB3L2,GCG |
| AMPK signaling pathway | PFKFB4,PRKAG2,STRADA,PPP2R5D,PFKFB2,SLC2A4,RAB8A,PFKM,PPP2R2B,PIK3R1 |
| mTOR signaling pathway | MAPK1,RHEB,HIF1A,PIK3CG,INS1,RPS6KB1,EIF4E1C,RRAGD,EIF4E1B,VEGFAA |
| Type II diabetes mellitus | SOCS3,IKBKB,INS,MAFA,MAPK10,PIK3R3,ADIPOQ,INS1,INS-IGF2,PDX1 |
| PIK-Akt signaling pathway | ITGA9,SGK1,PIK3CD,PDGFRA,MET,VTN,RXRA,HSP90B1,COL4A1,RPS6 |
| Progesterone-mediated oocyte maturation | FZR1,MAPK12,SPDYA,PPP1R2P9,CDC25C,PIK3CG,MAD2L1,PRKACBB,MAPK11,PIK3CB |
| Non-alcoholic fatty liver disease (NAFLD) | MAP3K5,MAPK10,GSK3B,RELA,COX7A2,CYCS,UQCRC1,NDUFA2,CEBPA,ATF4 |
Protein Function
Ins2 has several biochemical functions, for example, hormone activity,identical protein binding,insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins2 itself. We selected most functions Ins2 had, and list some proteins which have the same functions with Ins2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | POMCA,PRL4A1,EDN1,INHBAB,CSHL1,NPPB,UCN3,STC2A,PRL6A1,PTHLHA |
| insulin receptor binding | INS,IGF1R,PTPN1,DOK1B,PIK3R1,DOK3,FRS2B,PTPN11,DOK7,SHC1 |
| insulin-like growth factor receptor binding | ARRB1,SHC1,SOCS2,INSL4,IGF3,PIK3R1,IGF2B,GNAS,REN,IRS1 |
| identical protein binding | SIAH1A,FHIT,PSMA7,CRYBB2,IRF3,FGFR1,MDM2,IK,SERPINA1D,CHMP4A |
| protein complex binding | LAMB3,C8A,KIF11,PPP4C,CDK4,CCNE1,PAFAH1B1,FADD,PPIB,NCKAP1 |
| protease binding | ADAM8A,ECM1,SELL,ITGB1,DPP4,SERPINA1A,HSPA6,ITGA3,DERL1,PANX1 |
Interacting Protein
Ins2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins2.
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