KCNC2

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KCNC2

Official Full Name potassium voltage-gated channel, Shaw-related subfamily, member 2
Background The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Three transcript variants encoding three different isoforms have been found for this gene.
Synonyms KCNC2; potassium voltage-gated channel, Shaw-related subfamily, member 2; potassium voltage-gated channel subfamily C member 2; Kv3.2; voltage-gated potassium channel Kv3.2; MGC138196
    • Species :
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat KCNC2-3174R Recombinant Rat KCNC2 Protein Mammalian Cell His
    Zebrafish KCNC2-5618Z Recombinant Zebrafish KCNC2 Mammalian Cell His

    KCNC2 involved in several pathways and played different roles in them. We selected most pathways KCNC2 participated on our site, such as Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Integration of energy metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glucagon-like Peptide-1 (GLP1) regulates insulin secretion GCGB; RAPGEF3; KCNC2; GNB5A; KCNB1; GCGA; KCNS3A; RAPGEF4; KCNS3; GNB5B
    Integration of energy metabolism RAPGEF4; SYT5; KCNB1; AKAP5; MARCKSA; RAPGEF3; MARCKSB; KCNC2; KCNS3; KCNS3A
    Metabolism NUDT4A; PDK2B; CTRC; ACSF3; PPM1LB; LMF2; B3GNT1; AKR1C4; MPC1; Agmo
    Neuronal System KCNMA1; HCN4; KCNJ8; NSFB; KCNF1; DLG3; KCNK7; RERG; ABCC9; SLC1A2A
    Potassium Channels KCNC1; KCNA1; KCNK4; KCNN3; KCNK3A; KCNMA1; KCNV1; KCNN1B; KCNA6A; KCNJ1A.3
    Regulation of insulin secretion MARCKSB; KCNS3; KCNS3A; KCNB1; KCNC2; SYT5; MARCKSA; ARL2BP; ARL2
    Voltage gated Potassium channels KCNH2; KCNAB1A; KCNA10; KCNA6A; KCNG1; KCNF1A; KCNH5; KCNH1A; KCNQ3; KCNS3

    KCNC2 has several biochemical functions, for example, delayed rectifier potassium channel activity, ion channel activity, potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNC2 itself. We selected most functions KCNC2 had, and list some proteins which have the same functions with KCNC2. You can find most of the proteins on our site.

    Function Related Protein
    delayed rectifier potassium channel activity KCND1; KCNB1; KCNH1; KCNC1A; KCNB2; KCNC3A; KCNC4; KCNV1; KCNS3A; KCNC3B
    ion channel activity TRPC2; KCNV2B; FXYD2; RYR1B; CLCN6; GRIA4B; TRPM4A; TRPC5A; TRPC7A; KCNH5A
    potassium channel activity KCNK5A; KCNC1A; KCNG4A; KCNQ2; KCNIP1; KCNH6A; KCNK2B; KCNS3A; KCNK1B; KCNV2B
    voltage-gated ion channel activity CLIC4; KCNJ1A.3; KCNG4A; CLIC2; TRPM5; KCNC3A; KCNK16; CACNA1DA; TMEM109; CACNG7A
    voltage-gated potassium channel activity CNGA1; KCNA4; KCNAB1A; KCND2; KCNS3B; KCNQ2A; KCNH2; KCNG4A; KCNQ1; KCNA2

    KCNC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNC2.

    VEH, RW; LICHTINGHAGEN, R; et al. IMMUNOHISTOCHEMICAL LOCALIZATION OF 5 MEMBERS OF THE KV1 CHANNEL SUBUNITS - CONTRASTING SUBCELLULAR LOCATIONS AND NEURON-SPECIFIC CO-LOCALIZATIONS IN RAT-BRAIN. EUROPEAN JOURNAL OF NEUROSCIENCE 7:2189-2205(1995).

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