kcns3
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  • Official Full Name
  • potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
  • Background
  • Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family.
  • Synonyms
  • KCNS3; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; potassium voltage-gated channel subfamily S member 3; Kv9.3; voltage-gated potassium channel protein Kv9.3; voltage-gated potassium channel subunit Kv9.3; delayed-rectifier
Cat.#:KCNS3-284HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KCNS3, GST-tagged
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Cat.#:KCNS3-8552MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KCNS3 Protein
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Cat.#:KCNS3-3226RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KCNS3 Protein
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Involved Pathway

KCNS3 involved in several pathways and played different roles in them. We selected most pathways KCNS3 participated on our site, such as Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Integration of energy metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNS3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
KCNS3; RAPGEF4; KCNS3A; RAPGEF3; KCNB1; GNB5B; KCNC2; AKAP5; GCGA; GCGB
Integration of energy metabolism
KCNB1; GNB5A; GNG13A; GNG13B; KCNC2; RAPGEF3; MARCKSB; AKAP5; RAPGEF4; SYT5
Metabolism
CYGB1; CYP26A1; TM9SF1; OAZ3; SULT1C4; DHODH; FABP11A; MPC1; STARD5; AKR1B15
Neuronal System
SLC6A12; KCNA2B; ABCC9; KCNC4; KCNV1; KCNK2; SLC18A3A; KCNH2A; KCNJ1A.2; ARL6IP5A
Potassium Channels
KCNAB2; KCNQ2; KCNN1A; KCNV1; KCNA6; KCND2; KCNAB1A; KCNJ1A.2; KCNK6; KCNAB3
Regulation of insulin secretion
KCNS3; MARCKSA; KCNC2; ARL2BP; KCNS3A; SYT5; ARL2; MARCKSB; KCNB1
Voltage gated Potassium channels
KCNC1A; KCNH5A; KCNG4A; KCNAB1; KCNH6A; KCNA1; KCNA6; KCNS2; KCNV1; KCNS3

Protein Function

KCNS3 has several biochemical functions, for example, delayed rectifier potassium channel activity, potassium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNS3 itself. We selected most functions KCNS3 had, and list some proteins which have the same functions with KCNS3. You can find most of the proteins on our site.
Function
Related Protein
Function delayed rectifier potassium channel activity
Related Protein KCNS2; KCNV2; KCNC3A; KCNA5; KCNA10; KCNV2B; KCNC3B; KCNQ5; KCNC1; KCNH2
Function potassium channel regulator activity
Related Protein CHP; KCNAB2; AMIGO1; KCNE2; SGK3; KCNIP2; PRKCZ; KCNMB2; AKAP9; PIAS3

Interacting Protein

KCNS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNS3.
HSP90AB1