LAMP2
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Official Full Name
lysosomal-associated membrane protein 2
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Overview
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] -
Synonyms
LAMP2; lysosomal-associated membrane protein 2; LAMPB; CD107b; LAMP-2; LGP110; lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Chicken
- Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- LAMP2 Related Articles
- LAMP2 Related Research Area
LAMP2 involved in several pathways and played different roles in them. We selected most pathways LAMP2 participated on our site, such as Lysosome, Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Lysosome | AP4B1;GBA;NAGPA;GLA;ATP6AP1;PLA2G15;ATP6V0A2;AP3M1;AP1S3 |
Phagosome | H2-Q10;ATP6V1A;C1RA;LAMP2;STX7;TUBA2;ATP6V0CA;ATP6V1C1;TUBAL3 |
Tuberculosis | LAMP1;ITGB2;BAX;Il23a;RAF1;SPHK2;FCGR2C;CD14;ATP6V0A4 |
LAMP2 has several biochemical functions, for example, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMP2 itself. We selected most functions LAMP2 had, and list some proteins which have the same functions with LAMP2. You can find most of the proteins on our site.
Function | Related Protein |
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enzyme binding | EHHADH;XRCC1;MARCH6;ATP2A2;PLCB1;HAND2;CYP3A4;PICK1;PDE4D |
protein binding | CELF1;MAGEA3;CTF1;RNF24;CPSF4;DNA2;TUFT1;SH3GLB2;SEC23B |
LAMP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMP2.
LRRK2; RRAGB; RPTOR; PIAS4; b3xyc5_sollc; pi3p; cona_canen; ATP6V1A; Map1lc3b; SOD1; ADRB2; HSPA8; CLCN7; Sppl2a
- Q&As
- Reviews
Q&As (5)
Ask a questionLAMP2 may play a role in maintaining cardiac function and the clearance of damaged organelles in the heart, making it relevant to cardiovascular diseases.
Mutations in the LAMP2 gene can be identified through genetic testing, such as DNA sequencing.
Targeting LAMP2 function or expression may represent a potential therapeutic strategy for treating Danon disease and other lysosomal storage disorders.
LAMP2 deficiency has been associated with Danon disease, a rare genetic disorder characterized by cardiomyopathy, skeletal myopathy, and intellectual disability.
LAMP2 is involved in maintaining the integrity and stability of lysosomal membranes, as well as facilitating the fusion of lysosomes with autophagosomes during autophagy.
Customer Reviews (3)
Write a reviewLAMP2 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.
One aspect that sets the LAMP2 Protein apart is the excellent technical support provided by the manufacturer.
I have found the LAMP2 Protein to be highly stable, enabling long-term experiments without compromising its performance.
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