Recombinant Human LAMP2 Protein, His-tagged

• Cat.No.: LAMP2-233H
• Product Overview: Recombinant Human LAMP2(29-375aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Description: LAMP2, also known as lysosome-associated membrane glycoprotein 2 isoform A, is a major component of lysosomal membranes. It provides selectins with carbohydrate ligands. This protein mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. Deficiency of LAMP2 is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation.
• Source: Insect cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ala
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 39.4kDa (356aa) 57-70KDa (SDS-PAGE under reducing conditions.)
• Protein length: 29-375aa
• AA Sequence: ADPLELNLTD SENATCLYAK WQMNFTVRYE TTNKTYKTVT ISDHGTVTYN GSICGDDQNG PKIAVQFGPG FSWIANFTKA ASTYSIDSVS
  FSYNTGDNTT FPDAEDKGIL TVDELLAIRI PLNDLFRCNS LSTLEKNDVV QHYWDVLVQA FVQNGTVSTN EFLCDKDKTS TVAPTIHTTV
  PSPTTTPTPK EKPEAGTYSV NNGNDTCLLA TMGLQLNITQ DKVASVININ PNTTHSTGSC RSHTALLRLN SSTIKYLDFV FAVKNENRFY
  LKEVNISMYL VNGSVFSIAN NNLSYWDAPL GSSYMCNKEQ TVSVSGAFQI NTFDLRVQPF NVTQGKYSTA QDCSADDDNF HHHHHH
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Absorbance at 280)

Gene Information

• Gene Name: LAMP2 lysosomal-associated membrane protein 2 [ Homo sapiens ]
• Official Symbol: LAMP2
• Synonyms: LAMP2; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; CD107b; CD107 antigen-like family member B; lysosome-associated membrane protein 2; LAMPB; LAMP-2; LGP110
• Gene ID: 3920
• mRNA Refseq: NM_001122606
• Protein Refseq: NP_001116078
• MIM: 309060
• UniProt ID: P13473