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Recombinant Human LAMP2 Protein

Cat.No. : LAMP2-729H
Product Overview : Recombinant Human LAMP2(Leu29-Ile375), transcript variant C, was expressed in HEK293 cells.
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Description : The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.
Source : HEK293 cells
Species : Human
Form : Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Molecular Mass : 39.4 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Resuspend the protein to the desired concentration in proper buffer.
Gene Name : LAMP2 lysosomal-associated membrane protein 2 [ Homo sapiens ]
Official Symbol : LAMP2
Synonyms : LAMP2; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; CD107b; CD107 antigen-like family member B; lysosome-associated membrane protein 2; LAMPB; LAMP-2; LGP110;
Gene ID : 3920
mRNA Refseq : NM_001122606
Protein Refseq : NP_001116078
MIM : 309060
UniProt ID : P13473

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does LAMP2 protein function in the context of cardiovascular diseases? 06/10/2022

LAMP2 may play a role in maintaining cardiac function and the clearance of damaged organelles in the heart, making it relevant to cardiovascular diseases.

How are mutations in the LAMP2 gene detected in clinical practice? 05/01/2022

Mutations in the LAMP2 gene can be identified through genetic testing, such as DNA sequencing.

What are the potential therapeutic implications of targeting LAMP2 in Danon disease? 04/25/2022

Targeting LAMP2 function or expression may represent a potential therapeutic strategy for treating Danon disease and other lysosomal storage disorders.

What are the clinical implications of LAMP2 deficiency? 02/08/2018

LAMP2 deficiency has been associated with Danon disease, a rare genetic disorder characterized by cardiomyopathy, skeletal myopathy, and intellectual disability.

How is LAMP2 protein involved in lysosomal function? 05/25/2017

LAMP2 is involved in maintaining the integrity and stability of lysosomal membranes, as well as facilitating the fusion of lysosomes with autophagosomes during autophagy.

Customer Reviews (3)

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Reviews
12/20/2021

    LAMP2 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.

    12/11/2017

      One aspect that sets the LAMP2 Protein apart is the excellent technical support provided by the manufacturer.

      08/07/2016

        I have found the LAMP2 Protein to be highly stable, enabling long-term experiments without compromising its performance.

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