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Official Full Name mitogen-activated protein kinase 13
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Synonyms MAPK13; mitogen-activated protein kinase 13; PRKM13; p38delta; SAPK4; MAPK 13; MAP kinase 13; MAP kinase p38 delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; MGC99536
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAPK13-2436H Recombinant Human MAPK13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Mapk13-3940M Recombinant Mouse Mapk13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MAPK13-1285H Recombinant Human Mitogen-Activated Protein Kinase 13, His-tagged Human His
    Human MAPK13-31379TH Recombinant Human MAPK13, His-tagged E.coli His
    Human MAPK13-31380TH Recombinant Human MAPK13 N/A
    Human MAPK13-31H Recombinant human biotinylated MAPK13, His-tagged E.coli His
    Human MAPK13-357H Recombinant Human MAPK13 Protein, GST-tagged, Activated Insect Cell GST
    Human MAPK13-374H Recombinant Human MAPK13, GST-tagged, Active Sf9 Insect Cell GST
    Human MAPK13-383H Recombinant Human MAPK13 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MAPK13-48H Recombinant Human MAPK13, GST-tagged Sf9 Insect Cell GST
    Human MAPK13-574HCL Recombinant Human MAPK13 cell lysate Insect Cell N/A
    Human MAPK13-737H Recombinant Human Mitogen-activated Protein Kinase 13 E.coli N/A
    Human MAPK13-945H Recombinant Human MAPK13, GST tagged Insect Cell GST

    MAPK13 involved in several pathways and played different roles in them. We selected most pathways MAPK13 participated on our site, such as MAPK signaling pathway, Rap signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway ARRB1; FGF13; CACNG4; FGF11; AKT1; HSPA8; PRKCB; MAP2K4B; GNA12A; FGF10A
    Rap signaling pathway PFN1; PRKD2; APBB1IP; RAC3; RASSF5; FGF8; BCAR1; INSR; KIT; PFN2
    FoxO signaling pathway PLK3; IRS2; MAPK12A; MAP2K2B; PLK1; GADD45B; INSB; GABARAPL1; NLK1; MAPK12
    Sphingolipid signaling pathway PPP2R3C; ASAH2; GNAI2; RHOA; NRAS; AKT1; PLCB3; PIK3CG; SPTLC1; PIK3CA
    Adrenergic signaling in cardiomyocytes PIK3CD; RAPGEF3; CAMK2G; CALM; CREB3L4; CACNA1C; MAPK11; GNA15.4; PPP2R5E; ATP1B2A
    VEGF signaling pathway RAC1B; PPP3R2; AKT1; MAPK11; PTK2AB; MAPK14B; PLA2G4C; PLA2G4F; PIK3CA; MAP2K2A
    Osteoclast differentiation MAP2K1; MITF; IFNGR2; FCGR1; MAPK10; SIRPA; IKBKB; STAT2; MAPK13; IFNAR2
    Signaling pathways regulating pluripotency of stem cells PCGF2; AKT1; PCGF5; MAPK13; MAP2K1; WNT7A; WNT11; WNT4; BMPR1B; ESX1
    Platelet activation MYLK; FCGR2A; P2RX1; MAPK1; PLCB1; PTGIR; MAPK11; PRKCI; PRKACA; FYN
    Toll-like receptor signaling pathway PIK3CB; NFKBIAA; FOS; CD86; AKT2; MAPK14A; MAP2K2A; TLR8; Ifna11; NFKBIA
    NOD-like receptor signaling pathway CASPA; NFKBIB; MAPK13; IL6; MAPK8; MAPK3; NAIP6; NAIP7; IL8L2; CARD18
    RIG-I-like receptor signaling pathway IFNA21; ISG15; MAPK13; IFNPHI3; IL12B; IFNB1; MAPK12A; IFNA2; IKBKB; IFNA12
    T cell receptor signaling pathway ICOS; PIK3CA; PIK3R1; IKBKG; PAK7; CD3G; IL4; GSK3B; IL5; CBLB
    Fc epsilon RI signaling pathway GAB2; PIK3CD; RAC2; PLA2G4A; KRAS; MAP2K4; RAC1; PIK3CA; VAV2; IL13
    TNF signaling pathway PIK3CG; CCL2; IKBKB; CXCL2; TRADD; ICAM1; CXCL10; PTGS2; NFKBIA; MAPK9
    Leukocyte transendothelial migration CLDN22; CLDN23; ITGAL; PIK3CD; MAPK11; CXCR4; ACTN2; PTK2B; PTPN11; GNAI3
    Neurotrophin signaling pathway CALM1; PIK3R5; MAPK9; MAP2K7; PIK3R3; RPS6KA2; NTF4; MAPK1; NFKBIE; RELA
    Retrograde endocannabinoid signaling MAPK13; GNAQ; MAPK11; PRKACA; GNAI3; PLCB1; ITPR1; MAPK9; GABRA5; GABRB1
    Dopaminergic synapse GNG7; PRKACA; PLCB3; GNAO1; PPP2R5C; GNG12; GNB3; KIF5A; GNG4; DRD4
    Inflammatory mediator regulation of TRP channels MAPK10; PTGER4; IL1R1; TRPV3; NTRK1; HTR2B; F2RL1; PPP1CC; HTR2A; CALML5
    GnRH signaling pathway CACNA1C; MAP3K2; GNRHR1; NRAS; GNAS; MAP2K4A; MMP14B; CALM4; MAP2K6; MAPK14A
    Progesterone-mediated oocyte maturation PIK3R3B; PIK3R3A; INS1; GNAI2B; RPS6KA3A; AKT2L; PLK1; INS; GNAI2A; MAPK8
    Prolactin signaling pathway MAPK1; IRF1; MAPK12; STAT1; MAPK13; GALT; CSN2; SHC3; SHC1; AKT2
    Amyotrophic lateral sclerosis (ALS) CCS; TOMM40L; MAP3K5; GRIA1; GRIA2; PPP3R1; MAPK11; BAD; GRIN2B; MAPK13
    Epithelial cell signaling in Helicobacter pylori infection MAP3K14; RELA; ATP6V1G1; MAPK10; MET; ADAM17; ATP6V1E2; ATP6V1B1; IL-8; ATP6V0A1
    Shigellosis U2AF1; ELMO2; MAD2L2; SRC; RELA; PFN2; MAPK1; MAPK9; VCL; PFN3
    Salmonella infection CXCL2; MYH10; ARPC5A; MAPK14A; ACTB1; IFNG; CCL3; WASLA; CXCL3; PFN3
    Leishmaniasis PRKCB; TNF; PTGS2; C3; IL1B; H2-AB1; HLA-DRA; IFNGR1; HLA-DOB; ITGB2L
    Chagas disease (American trypanosomiasis) PIK3CD; IL-8; TGFB3; PPP2R1A; FAS; SMAD3; Il2; SMAD2; TNFRSF1A; GNAI3
    Toxoplasmosis HSPA1A; TAB2; Casp3; MAP2K3; TNFRSF1A; Toxoplasma Gondii Dense Granule Protein 7; PPIF; HLA-DMA; LAMA5; NFKB1
    Tuberculosis MAPK9; RAB7A; IRAK4; CALM2; MAPK12; RFXAP; IFNA10; CD209A; Ifna15; BID
    Influenza A CYCS; IFNA3; VDAC1; IL33; IFNA12; MAP2K1; TNF; MAP2K6; SOCS3; HLA-DPB1
    Epstein-Barr virus infection XPO1; AKAP8L; ITGAL; SKP2; PSMD4; PSMC2; TRAF3; HLA-DQA1; GTF2B; BCL2
    Proteoglycans in cancer WNT9A; WNT11; TLR4; PIK3CB; RAC1; MRAS; PRKACB; AKT1; CAV3; NRAS

    MAPK13 has several biochemical functions, for example, ATP binding, MAP kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPK13 itself. We selected most functions MAPK13 had, and list some proteins which have the same functions with MAPK13. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ORC5; NME7; P2RX4; CASKB; CDC34B; ABCC6; PTK6B; YME1L1; AURKB; AARS2
    MAP kinase activity MAPK3; NLK1; MAPK13; MAPK12B; MAPK11; MAPK1; MAPK4; MAPK7; MAPK12; MAPK14
    protein binding ZNF79; CPS1; BLOC1S2; C1orf109; APOA1; GUCY2C; PPP1R1A; CD6; KRT25; EPHA7
    protein serine/threonine kinase activity PIK3R4; SLC14A2; CSNK1D; ACVR2B; STK32A; TAOK3; STK38L; GSK3A; UHMK1; CASK

    MAPK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPK13.

    PRKD1; FPR1; saicar; PKM; ATF2; MAPKAPK3; Pkd1; MAP3K4; GPX4; SMAD4; ANKLE2; AKIP1; pi3p

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