• Official Full Name
  • major histocompatibility complex, class I-related
  • Background
  • Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
  • Synonyms
  • MR1; major histocompatibility complex, class I-related; HLALS, major histocompatibility complex, class I like sequence; major histocompatibility complex class I-related gene protein; Class I histocompatibility antigen like protein; HLALS; Major histocompatibility complex class I like sequence; Major histocompatibility complex class I related; Major histocompatibility complex class I related isoform CRA a; Major histocompatibility complex class I related isoform CRA c; Major histocompatibility complex class I related isoform CRA d; MHC class I like antigen MR 1; MHC class I like antigen MR1; MHC class I related protein 1 isoform B; MHC class I related protein 1 isoform C; MR 1; Mr1 protein; MR1B; MR1C; OTTHUMP00000033129; OTTHUMP00000033130; OTTHUMP00000033131; MHC class I-like antigen MR-1; MHC class I-related gene protein; MHC class-I related-gene protein; class I histocompatibility antigen-like
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MR1 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MR1, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MR1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MR1 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MR1
Source (Host):Species:Human
Product nameRecombinant Human MR1 293 Cell Lysate

Protein Function

MR1 has several biochemical functions, for example, MHC class I receptor activity, peptide antigen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MR1 itself. We selected most functions MR1 had, and list some proteins which have the same functions with MR1. You can find most of the proteins on our site.
Related Protein
Function MHC class I receptor activity
Related Protein LILRB1; KIR3DS1; MR1; KLRF1; CD160
Function peptide antigen binding
Related Protein HLA-F; HLA-G; TRGV3; TUBB3; HLA-C; H2-AB1; DHCR24; MHC1ZFA; HLA-DRB3; AZGP1
Function protein binding
Related Protein SLC30A8; JAM3B; PLAT; CCL4; MKI67IP; UQCC1; APBB1; XPO1; BCL2L2; CHEK1

Interacting Protein

MR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MR1.

MR1 Related Articles

Mariati; Koh, EYC; et al. Toward stable gene expression in CHO cells Preventing promoter silencing with core CpG island elements. BIOENGINEERED 5:340-345(2014).
Mariati; Yeo, JHM; et al. Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells. BIOTECHNOLOGY PROGRESS 30:523-534(2014).