Recombinant Human MR1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MR1-4423H
• Product Overview: MR1 MS Standard C13 and N15-labeled recombinant protein (NP_001522) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.2 kDa
• AA Sequence: MGELMAFLLPLIIVLMVKHSDSRTH SLRYFRLGVSDPIRGVPEFISVGYV DSHPITTYDSVTRQKEPRAPWMAEN LAPDHWERYTQLLRGWQQMFKVELK RLQRHYNHSGSHTYQRMIGCELLED GSTTGFLQYAYDGQDFLIFNKDTLS WLAVDNVAHTIKQAWEANQHELLYQ KNWLEEECIAWLKRFLEYGKDTLQR TEPPLVRVNRKETFPGVTALFCKAH GFYPPEIYMTWMKNGEEIVQEIDYG DILPSGDGTYQAWASIELDPQSSNL YSCHVEHCGVHMVLQVPQESETIPL VMKAVSGSIVLVIVLAGVGVLVWRR RPREQNGAIYLPTPDRTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MR1 major histocompatibility complex, class I-related [ Homo sapiens (human) ]
• Official Symbol: MR1
• Synonyms: MR1; major histocompatibility complex, class I-related; HLALS, major histocompatibility complex, class I like sequence; major histocompatibility complex class I-related gene protein; MHC class I-like antigen MR-1; MHC class I-related gene protein; MHC class-I related-gene protein; class I histocompatibility antigen-like protein; major histocompatibility complex, class I-like sequence; HLALS; FLJ31593
• Gene ID: 3140
• mRNA Refseq: NM_001531
• Protein Refseq: NP_001522
• MIM: 600764
• UniProt ID: Q95460