Recombinant Full Length Human MR1 Protein, C-Flag-tagged

• Cat.No.: MR1-609HFL
• Product Overview: Recombinant Full Length Human MR1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 39.2 kDa
• AA Sequence: MGELMAFLLPLIIVLMVKHSDSRTH SLRYFRLGVSDPIRGVPEFISVGYV DSHPITTYDSVTRQKEPRAP WMAENLAPDHWERYTQLLRGWQQMF KVELKRLQRHYNHSGSHTYQRMIGC ELLEDGSTTGFLQYAYDGQD FLIFNKDTLSWLAVDNVAHTIKQAW EANQHELLYQKNWLEEECIAWLKRF LEYGKDTLQRTEPPLVRVNR KETFPGVTALFCKAHGFYPPEIYMT WMKNGEEIVQEIDYGDILPSGDGTY QAWASIELDPQSSNLYSCHV
  EHCGVHMVLQVPQESETIPLVMKAV SGSIVLVIVLAGVGVLVWRRRPREQ NGAIYLPTPDRTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: MR1 major histocompatibility complex, class I-related [ Homo sapiens (human) ]
• Official Symbol: MR1
• Synonyms: HLALS
• Gene ID: 3140
• mRNA Refseq: NM_001531.3
• Protein Refseq: NP_001522.1
• MIM: 600764
• UniProt ID: Q95460