mbl1
Share
  • Official Full Name
  • mannose-binding lectin (protein A) 1
  • Background
  • MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa andfungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system.Another important function of MBL is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.
  • Synonyms
  • MBL1; mannose-binding lectin (protein A) 1; mannose-binding protein A; mannose binding lectin (A); MBP A; S MBP; raRF p28B; mannan-binding protein; mannose binding lectin, serum (A); ra-reactive factor polysaccharide-binding component p28B; MBL-A; MBP-A; S-MBP
Cat.#:Mbl1-803MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Mbl1, His tagged
+Inquiry
Cat.#:Mbl1-20RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Mbl1, Fc tagged
+Inquiry
Cat.#:MBL1-3602RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MBL1 Protein
+Inquiry
Cat.#:MBL1-2776MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse MBL1 cell lysate
+Inquiry
Cat.#:MBL1-1113RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat MBL1 cell lysate
+Inquiry

Involved Pathway

Mbl1 involved in several pathways and played different roles in them. We selected most pathways Mbl1 participated on our site, such as Phagosome, Complement and coagulation cascades, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mbl1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
SEC61A1; ACTB2; ACTB1; ATP6V1A; CTSLA; SEC22B; TUBA8L; SEC22BA; TUBA4A; RAB5AA
Complement and coagulation cascades
C3; C5; PLG; MBL1; Serpina1b; F11; MBL2; C8G; SERPINA1D; CFH
Staphylococcus aureus infection
CFI; C5; C1RA; FCGR4; PTAFR; MASP1; HLA-DQA1; GM5077; HLA-DRB4; SELP

Protein Function

Mbl1 has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Mbl1 itself. We selected most functions Mbl1 had, and list some proteins which have the same functions with Mbl1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PRKCSH; SYT12; KCNIP1; PPP3CA; AMY2A; PCDH1G26; MMP15; EMR2; PCDHB11; RGN
Function calcium-dependent protein binding
Related Protein VLDLR; S100A1; ANXA4; RBM22; MYO1D; S100B; CLEC4M; SNAP25; STX2; A2M
Function carbohydrate binding
Related Protein GALNT1; KLRC1; DGCR2; MGAT2; SIGLEC14; ASGR2; GALNTL4; CHI3L2; SELL; GALNT5
Function mannose binding
Related Protein LMAN2; MRC1; LMAN2L; CLN5; MBL1; CD209C; LMAN1; CLEC4M; M6PR; MBL2
Function phosphatidylinositol-4-phosphate binding
Related Protein RS1; SNX3; MBL1; JPH2; LANCL2; CLSTN2; GOLPH3; SNX24; COL4A3BP; PRRC2B
Function polysaccharide binding
Related Protein ENDOU; PRG4B; TINAG; TINAGL1; C8orf84; ENPP2; PRG4A; CLEC18A; PRG4; ENPP1
Function protease binding
Related Protein CCDC71L; ADAM8A; FADD; SERPINB13; LDLR; XBP1; SERPINE1; RNF139; INS; SELL
Function protein homodimerization activity
Related Protein NPPC; TCF4; SH3GLB1; ABCD3; SLC14A2; PAFAH1B2; IL6R; MCL1B; GRPEL1; MITD1