nrip1
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  • Official Full Name
  • nuclear receptor interacting protein 1
  • Background
  • Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]
  • Synonyms
  • NRIP1; nuclear receptor interacting protein 1; RIP140; nuclear receptor-interacting protein 1; nuclear factor RIP140; receptor interacting protein 140; receptor-interacting protein 140;
Cat.#:NRIP1-10890MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NRIP1 Protein
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Cat.#:NRIP1-3695HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NRIP1 293 Cell Lysate
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Involved Pathway

NRIP1 involved in several pathways and played different roles in them. We selected most pathways NRIP1 participated on our site, such as Adipogenesis, BMAL1:CLOCK,NPAS2 activates circadian gene expression, Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRIP1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
CELF1; CEBPA; EGR2B; NAMPT; EBF1; CTNNB1; HMGA1-RS1; KLF6; MBNL1; DDIT3
BMAL1:CLOCK,NPAS2 activates circadian gene expression
DBP; CREBBP; HELZ2; NAMPT; NCOA2; NRIP1; CARM1; CRY2; CRY1
Circadian Clock
CARM1; HELZ2; CRY2; CPT1A; NAMPT; DBP; CSNK1E; CRY1; NRIP1; RAI1
Coregulation of Androgen receptor activity
KDM1A; CARM1; MAK; SNURF; CMTM2; TCF4; CMTM2A; PA2G4; KDM3A; TGFB1I1
FOXA1 transcription factor network
NRIP1; NFIA; NFIB; FOXA1; NR2F2; AP1B1; CEBPB; TFF1; POU2F1; CYP2C18
Ovarian Infertility Genes
NRIP1; ZP3; MSH5; GJA4; ZP2; SYNE2; INHA; DAZL; DMC1; NR5A1
RORA activates gene expression
NRIP1
Retinoic acid receptors-mediated signaling
NRIP1; RBP1

Protein Function

NRIP1 has several biochemical functions, for example, androgen receptor binding, core promoter sequence-specific DNA binding, estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRIP1 itself. We selected most functions NRIP1 had, and list some proteins which have the same functions with NRIP1. You can find most of the proteins on our site.
Function
Related Protein
Function androgen receptor binding
Related Protein KDM1A; FOXP1; PRKCB; KAT5; GRIP1; FHL2; CDK7; FOXH1; NSD1; KDM4C
Function core promoter sequence-specific DNA binding
Related Protein CRY1; ATF4; SP1; NFYA; PRMT5; ESR1; PROX1; SIRT1; ZFHX3; PPARG
Function estrogen receptor binding
Related Protein STRN; DYX1C1; CCDC62; PCNA; PPARGC1A; XBP1; FUS; DDX54; NRIP1; PRMT2
Function glucocorticoid receptor binding
Related Protein FKBP4; EP300; STAT5B; STAT3; YWHAH; GRIP1; CEBPB; ETS2; NR4A2; NRIP1
Function histone deacetylase binding
Related Protein HES1; SIRT2; GLI3; WDTC1; CDC20; YWHAE; MYOCD; MAGEA2; PRDM1; HDAC10
Function nuclear hormone receptor binding
Related Protein Ankar; SIRT1; NRIP1; MYOD1; EP300; TACC2; NCOA2; BUD31; SNW1; NCOA3
Function protein binding
Related Protein TMED5; APPL1; MME; COMMD6; TMEM106C; ATP5G1; KPNA4; DUSP2; SLC35F6; A1CF
Function retinoid X receptor binding
Related Protein NR0B2; NRIP1; NR4A2; NCOR1; HMGA1-RS1; NR1H2; RARB; FUS; VDR; RARG
Function transcription coactivator activity
Related Protein RXRA; SETD3; SIX3; RNF4; NEUROD1; GATA3; MED20; MKL1B; PIAS2; WWC1
Function transcription corepressor activity
Related Protein DDIT3; ZNF136; SSX2; E2F8; MXD4; CTBP2; DAXX; LHX1; E2F6; BATF3

Interacting Protein

NRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRIP1.
RARA; FHL1; LDOC1; CEP70; PRMT1

NRIP1 Related Articles

Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
Pisetsky, DS; et al. The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. AUTOIMMUNITY 47:487-493(2014).