nxf2
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  • Official Full Name
  • nuclear RNA export factor 2
  • Background
  • This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.
  • Synonyms
  • NXF2; nuclear RNA export factor 2; cancer/testis antigen 39; CT39; TAP like protein 2; TAPL 2; FLJ20416; TAPL2; OTTHUMP00000023710; OTTHUMP00000023711; OTTHUMP00000023712; TAP-like protein 2; t-complex protein 11 homolog; NXF2B; TAPL-2
Cat.#:NXF2-1977HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NXF2 Protein, His-tagged
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Cat.#:NXF2-3621HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NXF2 293 Cell Lysate
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Involved Pathway

NXF2 involved in several pathways and played different roles in them. We selected most pathways NXF2 participated on our site, such as Ribosome biogenesis in eukaryotes, RNA transport, mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NXF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome biogenesis in eukaryotes
NXF2; RPP25; LOC81691; NHP2L1A; XRN1; GNL3L; CIRH1A; DROSHA; SPATA5; NHP2
RNA transport
RANGAP1; EIF4E2RS1; SMN1; MAGOH; RANGAP1A; KPNB1; RPP38; EIF2S1B; NUP88; RPP25L
mRNA surveillance pathway
UPF3B; PPP2CA; pab1; PPP2R5D; CSTF2T; GSPT2; MSI2A; WDR33; NCBP2; MSI2
Influenza A
NXT2; IFNA13; LOC100033925; SLC25A6; AGFG1; IFNAR1; IKBKE; FDPS; EIF2AK2; IRF7
Herpes simplex infection
IFNA5; EP300; PVRL2; TNF; TRAF2; CYCSB; IFNAR1; TLR3; CUL1; IL6

Protein Function

NXF2 has several biochemical functions, for example, mRNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NXF2 itself. We selected most functions NXF2 had, and list some proteins which have the same functions with NXF2. You can find most of the proteins on our site.
Function
Related Protein
Function mRNA binding
Related Protein EIF4A3; KHSRP; CELF1; HSP26; PCBP1; AGO2; PCF11; NCBP2; RPL7; PIWIL2
Function nucleotide binding
Related Protein SART3; SEPT7B; ARF1L; MYH4; CSNK2A2A; ABCF2A; WEE2; Abca2; UBE2NB; CAMK1GB
Function poly(A) RNA binding
Related Protein PDIA3; DUT; ZC3H11A; SRP19; VSIG8; RCC2; TOP1; ISG20L2; RAN; PEG10
Function protein binding
Related Protein ERLIN2; FANCF; ERO1L; CARKD; C20orf20; SETMAR; FLT3; RPS25; CALU; ZMYND11

Interacting Protein

NXF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXF2.
Nxt1