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NXF2

Official Full Name

nuclear RNA export factor 2
Overview

This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.
Synonyms

NXF2; nuclear RNA export factor 2; cancer/testis antigen 39; CT39; TAP like protein 2; TAPL 2; FLJ20416; TAPL2; OTTHUMP00000023710; OTTHUMP00000023711; OTTHUMP00000023712; TAP-like protein 2; t-complex protein 11 homolog; NXF2B; TAPL-2;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NXF2-3621HCL	Recombinant Human NXF2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NXF2-1977H	Recombinant Human NXF2 Protein, His-tagged	E.coli	His		Inquiry
Human	NXF2-2520H	Recombinant Human NXF2 Protein, His-tagged	E.coli	N-His	Leu391-Ser625	Inquiry
Mouse	Nxf2-1874M	Recombinant Mouse Nxf2 Protein, His-tagged	E.coli	N-His	Leu454-Lys685	Inquiry

Involved Pathway
Protein Function
Interacting Protein

NXF2 involved in several pathways and played different roles in them. We selected most pathways NXF2 participated on our site, such as Ribosome biogenesis in eukaryotes, RNA transport, mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NXF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome biogenesis in eukaryotes	XRN2;WDR36;NXF2;NXF3;UTP15;TCOF1;RAN;RIOK2;GNL2
RNA transport	SUMO1;TRNT1;NUP98;EIF3S10;PAIP1;FXR1;EIF3HB;RPP25;NCBP2
mRNA surveillance pathway	PPP1CC;NXF2;PPP2R5A;NXF3;CPSF3;DAZAP1;HBS1L;NXT2;PPP2R3A
Influenza A	ICAM1;IFNA4;BCL2L2-PABPN1;CXCL8;IFNA16;IL-8;HLA-DQB1;IRF9;EP300
Herpes simplex infection	TNFSF14;NFKBIAB;H2-Q10;Ifna11;IRF7;RELA;CYCSB;TTC6;OAS1B

NXF2 has several biochemical functions, for example, mRNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NXF2 itself. We selected most functions NXF2 had, and list some proteins which have the same functions with NXF2. You can find most of the proteins on our site.

Function	Related Protein
mRNA binding	SRRM4;RPS26;FMR1;G3BP1;PCF11;SLBP;CELF1;TDRD7;RPS13
nucleotide binding	SRSF11;ACTA1A;PPIL4;HPRT1;U2AF2;RBM14A;ORC4;MYEF2;ABCA5
poly(A) RNA binding	CKAP4;RPGR;TBL3;CELF1;FLYWCH2;CCDC9;DHX33;HERC5;ALG13
protein binding	GNS;HMGCR;RAD51D;TTC9C;LIN37;POLR1B;CETN1;ITGB3B;C1orf94

NXF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXF2.

Nxt1