p2rx5
Share
  • Official Full Name
  • purinergic receptor P2X, ligand-gated ion channel, 5
  • Background
  • The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3).
  • Synonyms
  • P2RX5; purinergic receptor P2X, ligand-gated ion channel, 5; P2X purinoceptor 5; P2X5; ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; MGC47755; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; OTTHUMP00000115870; OTTHUMP00000241718; OTTHUMP00000241719; OTTHUMP00000241720; OTTHUMP00000241722; OTTHUMP00000241723; lymphoid-restricted histocompatibility antigen-1; LRH-1
Cat.#:P2RX5-1492HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human P2RX5, GST-tagged
+Inquiry
Cat.#:P2RX5-4230RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat P2RX5 Protein
+Inquiry
Cat.#:P2RX5-6313CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken P2RX5
+Inquiry
Cat.#:P2RX5-9763ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish P2RX5
+Inquiry
Cat.#:P2RX5-3497HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human P2RX5 293 Cell Lysate
+Inquiry
Cat.#:P2RX5-3498HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human P2RX5 293 Cell Lysate
+Inquiry

Involved Pathway

P2RX5 involved in several pathways and played different roles in them. We selected most pathways P2RX5 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX5 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
BDKRB1; RYR1; PHKA2; PTAFR; GRIN1B; PLCD3; TRHR2; P2RX3B; DRD1; P2RX2
Neuroactive ligand-receptor interaction
S1PR5A; TAAR1; GABRA4; MTNR1A; SSTR1; EDNRAA; GPR35; P2RX3; P2RX8; PARD3

Protein Function

P2RX5 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX5 itself. We selected most functions P2RX5 had, and list some proteins which have the same functions with P2RX5. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ACSL1; YARS2; SPEG; UBE2D1; ATP1A3B; ABCC5; Adcy4; Ckmm; ULK3; TPK1
Function extracellular ATP-gated cation channel activity
Related Protein P2RX1; NNR; P2RX4; P2RX4A; P2RX3A; P2RX3; P2RX6; P2RX5; P2RX8; P2RX7
Function ion channel activity
Related Protein KCNH1B; KCNH5; KCNF1A; RYR1B; KCNH5A; GJD3; CHRNB3A; HTR3B; CLCN3; SCN1LAB
Function purinergic nucleotide receptor activity
Related Protein P2RX4; P2RX8; P2RX3A; P2RX3; P2RX6; P2RX2; P2RX1; P2RX7; NNR; P2RX4B
Function transmembrane signaling receptor activity
Related Protein CLEC2H; OR4N4; CD3G; DARC; RYK; FCGR2C; BCAM; NPC1; GP6; OR4C12

Interacting Protein

P2RX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX5.
thrC