|Official Full Name||protein phosphatase 2, regulatory subunit B, epsilon isoform|
|Background||The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.|
|Synonyms||PPP2R5E; protein phosphatase 2, regulatory subunit B, epsilon isoform; protein phosphatase 2, regulatory subunit B (B56), epsilon isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; 2A5E_HUMAN; Epsilon isoform of regulatory subunit B56 protein phosphatase 2A; PP2A B subunit B epsilon; PP2A B subunit B epsilon isoform; PP2A B subunit B56 epsilon; PP2A B subunit B56 epsilon isoform; PP2A B subunit isoform B-epsilon; PP2A B subunit isoform B56-epsilon; PP2A B subunit isoform PR61-epsilon; PP2A B subunit isoform R5-epsilon; PP2A B subunit PR61 epsilon; PP2A B subunit PR61 epsilon isoform; PP2A B subunit R5 epsilon; PP2A B subunit R5 epsilon isoform; Protein phosphatase 2 regulatory subunit B (B56) epsilon isoform; Protein phosphatase 2 regulatory subunit B epsilon isoform; Regulatory subunit B of protein phosphatase 2 epsilon isoform; Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit epsilon; OTTHUMP00000179057; OTTHUMP00000245210; PP2A, B subunit, B epsilon; PP2A, B subunit, R5 epsilon; PP2A, B subunit, B56 epsilon; PP2A, B subunit, PR61 epsilon; epsilon isoform of regulatory subunit B56, protein phosphatase 2A; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, epsilon|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PPP2R5E involved in several pathways and played different roles in them. We selected most pathways PPP2R5E participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R5E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|mRNA surveillance pathway||PABPC1; SMG7; MSI2B; PABPN1; CPSF3; SRRM1; WDR33; DAZAP1; PPP2R5EB; SMG1|
|Sphingolipid signaling pathway||NSMAF; FYN; MAPK13; TNF; LOC100328615; ASAH2; PIK3CA; SPTLC1; PRKCZ; FCER1G|
|Oocyte meiosis||SPDYB; PPP1R2P9; INS2; PPP3CC; CDC20; ANAPC4; PPP2R5A; YWHAE1; CUL1; IGF1|
|PIK-Akt signaling pathway||GNG2; THBS1; AKT1; IL3RA; MAP2K2; TNC; FGF19; RPS6KB1; F2R; IL2RG|
|AMPK signaling pathway||CCND1; STK11; CREB5; PPARGC1A; PPP2R2B; SREBF1; LEPR; EIF4EBP1; EEF2; PFKFB3|
|Adrenergic signaling in cardiomyocytes||SCN5A; BCL2; GNAI1; ATP1B3; AGTR1B; ATF4B1; ATP1B4; ATF2; ATP1B3A; CREB3L3A|
|Dopaminergic synapse||ITPR1; GRIA1; GNG3; PPP2R1A; PLCB3; GNG5; GNG8; KCNJ6; MAOA; PPP2R5D|
PPP2R5E has several biochemical functions, for example, protein binding, protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R5E itself. We selected most functions PPP2R5E had, and list some proteins which have the same functions with PPP2R5E. You can find most of the proteins on our site.
|protein binding||STAU2; CLCF1; LHX4; CLIC5; EGLN3; TAF9; TCOF1; MYO1E; ZNF18; FUS|
|protein phosphatase type 2A regulator activity||PPME1; PPP2R1B; PPP2R4; PPP2R3A; PPP2R1A; EIF2AK2; PPP2R5A; PPP2R2A; SET; PPP2R5C|
PPP2R5E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R5E here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R5E.
PPP2R1A; PPP2CA; PPP2R1B; RACGAP1; DZIP1; Soga1