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PPP6R1

Official Full Name

protein phosphatase 6, regulatory subunit 1
Overview

Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits;by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the;holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725);(Stefansson and Brautigan, 2006 (PubMed 16769727)).
Synonyms

PPP6R1; protein phosphatase 6, regulatory subunit 1; KIAA1115 , SAPS domain family, member 1 , SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1; SAP190; PP6R1; SAPS domain family, member 1; SAPS1; KIAA1115;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	PPP6R1-2808H	Recombinant Human PPP6R1 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	PPP6R1-3278H	Recombinant Human PPP6R1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	PPP6R1-13277M	Recombinant Mouse PPP6R1 Protein	Mammalian Cell	His	Inquiry
Mouse	Ppp6r1-5086M	Recombinant Mouse Ppp6r1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Mouse	PPP6R1-7047M-B	Recombinant Mouse PPP6R1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	PPP6R1-7047M	Recombinant Mouse PPP6R1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein

PPP6R1 involved in several pathways and played different roles in them. We selected most pathways PPP6R1 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Asparagine N-linked glycosylation	SCFD1;ST3GAL3A;NANP;TRAPPC10;BET1;NAPB;NEU3;NSFB;ST6GALNAC2
COPII (Coat Protein 2) Mediated Vesicle Transport	ANKRD28;TRAPPC9;NAPAA;USO1;LMAN2L;PPP6R3;PREB;GORASP1;CTSZ
ER to Golgi Anterograde Transport	SERPINA1L;TMED2;NAPAB;TRAPPC1;LMAN2;ANKRD28;GORASP1;TRAPPC9;TRAPPC10
Membrane Trafficking	COPG;EXOC5;CLINT1;LMAN2L;GORASP1;TMED10;BLOC1S6;AP3S1;MYO6B
Metabolism of proteins	B3GNT2A;SMC6;SPON1;GATA6;DPH3;SLC35A1;GFER;GALNT5;CXXC1
Post-translational protein modification	NAPAB;ADAMTS18;SEC22C;ADAMTS1;PHC1;LMAN2L;ALG10B;ADAMTSL1;MAN1B1
Transport to the Golgi and subsequent modification	YKT6;TRAPPC2;TRAPPC1;LMAN2L;MGAT4B;SCFD1;MGAT4A;BET1;MIA3
Vesicle-mediated transport	HIP1R;TRAPPC2;HP;AMBP;GJA8;ARCN1;TRAPPC10;COPB2;SNF8

PPP6R1 has several biochemical functions, for example, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6R1 itself. We selected most functions PPP6R1 had, and list some proteins which have the same functions with PPP6R1. You can find most of the proteins on our site.

Function	Related Protein
protein phosphatase binding	CDC27;RPA3;ANAPC7;GRB2;VCAN;CTNNB1;ITPR1;FLT4;NEK2

PPP6R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6R1.

PPP6C; ANKRD28; TFRC; TUBB; TUBA1B; PRKDC; TIAL1; CRYZ; GTF3C1; TRAP1; BLMH; MYPN; Rpgrip1l; SPG20; ANKRD44; ANKRD52; GCN1L1; ARHGEF2; TUBB6; SPATA5L1