PPP6R1 Protein, protein phosphatase 6, regulatory subunit 1


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Official Full Name protein phosphatase 6, regulatory subunit 1
Background Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits;by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the;holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725);(Stefansson and Brautigan, 2006 (PubMed 16769727)).
Synonyms PPP6R1; protein phosphatase 6, regulatory subunit 1; KIAA1115 , SAPS domain family, member 1 , SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1; SAP190; PP6R1; SAPS domain family, member 1; SAPS1; KIAA1115
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP6R1-2808H Recombinant Human PPP6R1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse PPP6R1-13277M Recombinant Mouse PPP6R1 Protein Mammalian Cell His

    PPP6R1 involved in several pathways and played different roles in them. We selected most pathways PPP6R1 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Asparagine N-linked glycosylation MPDU1; ST8SIA3; TRAPPC2L; TRAPPC6BL; ALG10B; SEC22A; SEC24A; TRAPPC2; SEC22C; CNIH
    COPII (Coat Protein 2) Mediated Vesicle Transport LMAN2L; AREG; TRAPPC6B; ANKRD28; NAPAB; NAPG; TRAPPC6BL; YKT6; PPP6C; SEC22A
    ER to Golgi Anterograde Transport TRAPPC2; TRAPPC3; CTSZ; SEC22C; TRAPPC9; PPP6R1; AREG; MIA3; TRAPPC6B; SEC16B
    Membrane Trafficking GORASP1; NSFA; SEC16B; DTNBP1B; EXOC1; LMAN2; EXOC3; GAK; GJB3; CX27.5
    Metabolism of proteins FURINA; TBCB; GALNT5; NAT8B; TIMM10; TGFBI; PFDN5; VBP1; ST6GALNAC1.2; SAMM50
    Post-translational protein modification ALG14; OTOP2; ADAMTS20; PPP6R3; TMED2; DNAJC24; MUC5AC; GALNT5; MGAT4B; ADAMTSL1
    Transport to the Golgi and subsequent modification MGAT4B; SEC22C; TRAPPC5; PPP6R1; CNIH; NAPB; TRAPPC6B; ANKRD28; MGAT4A; TRAPPC6BL
    Vesicle-mediated transport AP4B1; TBC1D8B; SCFD1; PICALMB; MIA3; NAPB; FTH1B; GJD3; PLDN; TRAPPC6A

    PPP6R1 has several biochemical functions, for example, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6R1 itself. We selected most functions PPP6R1 had, and list some proteins which have the same functions with PPP6R1. You can find most of the proteins on our site.

    Function Related Protein
    protein phosphatase binding PARD3; CSK; DRD1A; ROS1; ANAPC5; LCK; CDH5; FGF19; PPP1R3C; TRAF3

    PPP6R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6R1.


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