prkacg
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  • Official Full Name
  • protein kinase, cAMP-dependent, catalytic, gamma
  • Background
  • Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit.
  • Synonyms
  • PRKACG; protein kinase, cAMP-dependent, catalytic, gamma; cAMP-dependent protein kinase catalytic subunit gamma; PKACg; KAPCG_HUMAN; KAPG; PKA C gamma; PKA C-gamma; Protein kinase cAMP dependent catalytic gamma; Serine (threonine) protein kinase; OTTHUMP00000021422; serine(threonine) protein kinase
Cat.#:PRKACG-1948HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRKACG, GST-tagged
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Cat.#:PRKACG-30211THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKACG
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Cat.#:PRKACG-396HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PRKACG, GST-tagged, Active
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Cat.#:PRKACG-2867HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKACG 293 Cell Lysate
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Involved Pathway

PRKACG involved in several pathways and played different roles in them. We selected most pathways PRKACG participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKACG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
FGF20; CACNA2D3; TRAF6; CACNB3; MAP2K2; MAPKAPK2; CACNA1B; MKNK2B; ECSIT; FLNA
Ras signaling pathway
ELK1; FGF5; PLD1; RIN1; GNG11; FGF22; SHC4; SOS1; RASA3; RAP1B
Calcium signaling pathway
CCKBR; LHCGR; GRM1; AGTR1B; P2RX8; PRKCG; P2RX3; ATP2A2; ITPKA; ADRA1B
cAMP signaling pathway
RAC3; MAPK3; VAV2; GHRL; VAV3; HTR4; GPR81; ATP1A2; PRKACA; CALML5
Chemokine signaling pathway
Ccl9; RHOA; BCAR1; GNGT2; PLCB3; ROCK2; CCL15; CX3CL1; CCL20; WAS
Oocyte meiosis
CDC26; CALM1; PPP1CAB; CCNB1; CCNE1; PPP2R1A; YWHAZ; PKMYT1; PPP1R2P9; PLCZ1
Apoptosis
CASP8L1; CASP3B; PPP3CCA; PRKAR2AB; PPP3R2; PIK3R1; IL3; Gzmg; AIFM1; TRP53
Adrenergic signaling in cardiomyocytes
CACNA2D2; CACNG7; TNNC1A; ATP1B3B; SCN1BB; PIK3CA; CALM2; TPMA; ADCY1A; PPP1CA
Vascular smooth muscle contraction
MAPK1; CALM3; PLCB3; PRKCBB; CALM1A; PPP1CC; PLA2G2E; PPP1CA; PRKCA; PLA2G2D
Wnt signaling pathway
NFATC3; WNT7AA; CAMK2D; PRICKLE1; PRKACAA; PPP3R2; TBL1Y; WNT2BB; DKK1; MMP7
Hedgehog signaling pathway
GLI2B; GSK3AA; BTRC; PRKACB; CSNK1G2B; FBXW11; CSNK1G2; WNT7A; WNT2BB; WNT4A
Gap junction
ADRB3B; MAP2K2B; TUBA1L; RAF1; CX43; RAF1B; TUBA8L2; Pdgfa&Pdgfb; DRD2A; CDK1
Platelet activation
VASP; Adcy4; GNAQ; AKT1; PPP1CB; PIK3R2; GP6; P2RY1; STIM1; COL27A1
Circadian entrainment
GNAO1; PLCB3; CALML3; ADCYAP1R1; GNB3; GNG8; CAMK2G; GUCY1B3; GNAI3; GNAQ
Long-term potentiation
PRKACA; PPP3CB; CAMK4; GRIN2A; RPS6KA3; PLCB4; MAPK1; BRAF; PPP3CA; CALM4
Retrograde endocannabinoid signaling
GRM1; GABRB2; MAPK10; GRIA2; Adcy4; GABRR1; FAAH; GABRR3; PRKCG; GNGT2
Glutamatergic synapse
ITPR3; GRIN2B; SLC17A8; GRIN3B; GRM7; HOMER1; SLC1A1; GRIN2C; PPP3CB; GRIN3A
Cholinergic synapse
CAMK2G; ITPR1; KCNQ5; KCNQ1; CHRM5; KCNJ14; CHRM4; PRKACB; CREB3L3; GNAI1
Serotonergic synapse
CYP2C38; RAF1; PLA2G4C; MAOB; CYP4X1; PLA2G4F; HTR2B; HTR3E; GNAI3; ARAF
GABAergic synapse
SLC38A1; GABRB3; GNG10; GABRP; GABRA3; GABBR2; GNB1; SLC6A1; GABRB2; GLUL
Dopaminergic synapse
GNG5; ITPR1; DRD4; CALM1; DRD3; CALY; KIF5C; MAOA; GNGT2; PPP2R5C
Olfactory transduction
SLC24A4; PDE1A; CAMK2D; CNGA4; OLFR10; PRKG2; OR12D3; OLFR473; OLFR181; OR2A4
Taste transduction
TAS2R13; TAS2R143; TAS2R144; GNG13; SCNN1G; TAS2R114; KCNB1; TAS1R3; GRM4; GNAT3
Inflammatory mediator regulation of TRP channels
HTR2C; HRH1; PIK3CB; PIK3R2; IL1R1; PRKCA; NTRK1; IGF1; PLA2G4F; CAMK2A
Insulin signaling pathway
RAF1; EIF4E2; CBLB; PDE3B; MKNK2B; PRKAA1; MKNK1; PRKAR2AB; PPP1R3DA; PRKACAA
Insulin secretion
PLCB3; PDX1; KCNN3; KCNN2; PRKCB; PRKCA; KCNMB2; ATP1B2; PLCB4; CREB3L1
GnRH signaling pathway
SRC; CDC42L; PLD1; ADCY2B; GNRH3; CACNA1C; LHBETA1; PLD1A; MMP2; MAP3K3
Ovarian steroidogenesis
HSD3B1; GDF9; FSHR; ALOX5; LHCGR; SCARB1; PRKACG; ACOT2; BMP6; PLA2G4C
Progesterone-mediated oocyte maturation
CDC23; GNAIA; CPEB2; PKMYT1; HSP90AA1; CCNB3; PIK3R3B; CPEB3; PIK3CB; MAPK9
Estrogen signaling pathway
GNAI2; KCNJ6; PLCB2; MAP2K2; AKT2; PRKCD; GPR30; PLCB3; PLCB4; GNAI1
Melanogenesis
WNT5B; WNT9A; PRKACA; WNT4; MAP2K2; Fzd4; DCT; TYRP1B; WNT2BB; FZD9B
Thyroid hormone synthesis
SLC26A4; GPX8; ATP1A1; TSHB; ATP1B1; GPX5; TTF2; PLCB3; GNAS; DUOXA2
Thyroid hormone signaling pathway
NCOA1; MED30; RXRB; PLCB2; CASP9; HRAS; ATP1B4; ITGAV; NCOR1; MED14
Oxytocin signaling pathway
PLCB2; MAPK3; PIK3CD; ROCK2; GUCY1B3; CAMK2A; RCAN1; PPP1CC; HRAS; Adcy4
Glucagon signaling pathway
GCG; PHKA1; PRKAA1; CALM1; PCK1; PLCB1; SLC2A1; GYS2; AKT1; PPP3CC
Regulation of lipolysis in adipocytes
IRS2; GNAI2; PIK3CD; PIK3R1; INS; PNPLA2; FABP4; PRKG2; NPR1; PTGER3
Renin secretion
CLCA2; PPP3CA; GUCY1B3; CALM2; PLCB4; PTGER4; GUCY1A3; PDE1B; PPP3CB; ITPR3
Aldosterone synthesis and secretion
KCNK9; PRKD2; AGTR1B; ITPR1; ADCY6; GNAQ; Adcy4; AKR1C1; PRKD3; CYP21A1
Endocrine and other factor-regulated calcium reabsorption
KLK1B9; KLK1B5; ATP2B1; ATP1B4; RAB11A; KLK1B3; DNM2; KL; ATP1B1; KLK2
Vasopressin-regulated water reabsorption
CREB3L2; RAB5C; ARHGDIA; DYNLL1; DCTN4; DCTN6; GNAS; ARHGDIB; DYNC1LI1; AQP4
Salivary secretion
ATP2B4; CST1; ITPR1; PRKCA; ATP1A1; Adcy4; PLCB4; CST2; LPO; CST3
Gastric acid secretion
GNAS; ATP1B2; KCNJ16; MYLK4; PRKACA; PLCB4; ATP1A1; PRKACG; HRH2; EZR
Bile secretion
ADCY6; CFTR; GNAS; ATP1B4; NR0B2; ABCB1; NR1H4; SCARB1; HMGCR; ABCG8
Parkinsons disease
Casp3; COX7A2L; COX5A; NDUFS8; UBE2G2; COX8C; NDUFS6; CASP9; SLC25A6; SLC6A3
Prion diseases
SOD1; PRKACG; MAPK3; C5; C8G; PRNP; Hc; C6; STIP1; HSPA1A
Cocaine addiction
GNAI2; RELA; CDK5R1; BDNF; NFKB1; PRKACA; GRIN2B; DRD1A; ATF4; PRKACG
Amphetamine addiction
PPP3R2; ATF6B; FOS; SLC18A2; CREB3L4; CALM2; FOSB; STX1A; CALML5; CAMK2D
Morphine addiction
GNG4; GABRB2; GABRQ; GNAI1; ADORA1; GNAI3; LOC100328615; PDE7A; GNG3; PDE1C
Vibrio cholerae infection
ATP6V1H; PDIA4; PRKACG; MUC2; ATP6V0B; SEC61G; TJP1; PRKACA; KDELR3; ACTG1
Amoebiasis
TGFB1; HSPB1; COL4A3; C9; LAMB2; NOS2; Casp3; IFNG; IL1B; SERPINB1A
HTLV-I infection
PDGFA; PIK3CA; Pdgfa&Pdgfb; NRP1; GSK3B; NFATC2; PDGFB; ATF3; H2-AA; FZD1
Epstein-Barr virus infection
PIK3CA; NFKB1; MAP3K14; MAP2K4; TP53; IRF3; PIK3R3; HDAC2; POLR3K; AKT2
Pathways in cancer
CDH1; FGF17; RALBP1; FOXO1; RHOA; CBLC; MET; MITF; FGF14; FGF18
Viral carcinogenesis
TRAF3; PXN; PRKACA; ACTN3; VDAC3; GTF2B; KAT2A; HIST1H2BH; GTF2H4; HDAC7A
Proteoglycans in cancer
RAF1; ITGB5; MET; NUDT16L1; MAP2K1; SRC; PIK3CB; ITPR1; PPP1R12C; PLCG1
Dilated cardiomyopathy
ACTC1; ITGA8; ITGA5; CACNG8; CACNA2D4; LMNA; DAG1; CACNA2D1; CACNA2D2; RYR2

Protein Function

PRKACG has several biochemical functions, for example, ATP binding, cAMP-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKACG itself. We selected most functions PRKACG had, and list some proteins which have the same functions with PRKACG. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PKLR; PTK2B; NLRP14; ABCD2; ACVRL1; DNAH11; HIPK4; DGKB; NLRP3; TTN
Function cAMP-dependent protein kinase activity
Related Protein AKAP13; PRKX; PRKACA; PRKACB; PRKAA1; PRKACG; PRKAG1

Interacting Protein

PRKACG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKACG here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKACG.
CETP; CDK17; PRKACA

PRKACG Related Articles

Lee, JW; Chen, H; et al. Protein Kinase A-alpha Directly Phosphorylates FoxO1 in Vascular Endothelial Cells to Regulate Expression of Vascular Cellular Adhesion Molecule-1 mRNA. JOURNAL OF BIOLOGICAL CHEMISTRY 286:6423-6432(2011).
Yao, L; Fan, PD; et al. Dopamine and ethanol cause translocation of epsilon PKC associated with epsilon RACK: Cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways. MOLECULAR PHARMACOLOGY 73:1105-1112(2008).