PSMD5

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PSMD5

Official Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.
Synonyms PSMD5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5; 26S proteasome non-ATPase regulatory subunit 5; KIAA0072; S5B; 26S proteasome subunit S5B; 26S protease subunit S5 basic; MGC23145
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMD5-2747HCL Recombinant Human PSMD5 293 Cell Lysate HEK293 N/A
    Human PSMD5-39H Recombinant Human PSMD5 protein, His-tagged E.coli His
    Human PSMD5-423H Recombinant Human PSMD5 Protein, His-tagged E.coli His
    Mouse PSMD5-13596M Recombinant Mouse PSMD5 Protein Mammalian Cell His
    Cynomolgus Monkey PSMD5-825C Recombinant Cynomolgus PSMD5 Protein, His-tagged Mammalian Cell His
    Chicken PSMD5-2025C Recombinant Chicken PSMD5 Mammalian Cell His
    Zebrafish PSMD5-2352Z Recombinant Zebrafish PSMD5 Mammalian Cell His

    PSMD5 involved in several pathways and played different roles in them. We selected most pathways PSMD5 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    APC/C-mediated degradation of cell cycle proteins PSME3; PSMA8; ANAPC10; PSMD5; PSMD9; UBE2C; CDK2; AURKB; PSMD14; NEK2
    APC/C:Cdc20 mediated degradation of Securin PSMD10; UBE2C; PSMD9; PSMD14; PSMD5; ANAPC10; PSME3; PSMA8
    APC/C:Cdc20 mediated degradation of mitotic proteins UBE2C; PSMD10; PSME3; PSMA8; PSMD5; PSMD14; PSMD9; ANAPC10; NEK2
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 ANAPC10; PSMD14; PSMA8; PSMD9; UBE2C; PSMD10; AURKB; PSMD5; PSME3
    APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint PSMD14; PSMD5; NEK2; PSMD9; UBE2C; PSMD10; PSMA8; ANAPC10; PSME3
    ARMS-mediated activation FGF20A; DUSP10; FGFR1B; DAB2IPB; PAQR3B; DUSP2; SPRED1; NTF7; NRG2A; NRG4
    AUF1 (hnRNP D0) binds and destabilizes mRNA PSMD9; HNRNPD; PSMA8; EIF4G1; PSME3; PSMD10; PSMD5; PSMD14
    Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins PSME3; PSMD10; PSMD9; ANAPC10; PSMA8; PSMD14; UBE2C; NEK2; PSMD5

    PSMD5 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD5 itself. We selected most functions PSMD5 had, and list some proteins which have the same functions with PSMD5. You can find most of the proteins on our site.

    Function Related Protein
    protein binding APOD; KPNB1; FAM96A; ZIC3; RUFY1; PSMA4; RBP4; FECH; CREB3; RUNX1T1

    PSMD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD5.

    PSMC2; PSMC1; TFCP2

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