psmd5
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  • Official Full Name
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
  • Background
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.
  • Synonyms
  • PSMD5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5; 26S proteasome non-ATPase regulatory subunit 5; KIAA0072; S5B; 26S proteasome subunit S5B; 26S protease subunit S5 basic; MGC23145
Cat.#:PSMD5-423HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMD5 Protein, His-tagged
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Cat.#:PSMD5-39HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMD5 protein, His-tagged
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Cat.#:PSMD5-13596MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PSMD5 Protein
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Cat.#:PSMD5-825CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PSMD5 Protein, His-tagged
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Cat.#:PSMD5-2025CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PSMD5
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Cat.#:PSMD5-2352ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PSMD5
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Cat.#:PSMD5-2747HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PSMD5 293 Cell Lysate
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Involved Pathway

PSMD5 involved in several pathways and played different roles in them. We selected most pathways PSMD5 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
APC/C-mediated degradation of cell cycle proteins
PSMD5; NEK2; PSMD10; CDK2; UBE2C; PSMA8; AURKB; PSME3; ANAPC10; PSMD14
APC/C:Cdc20 mediated degradation of Securin
ANAPC10; PSME3; PSMD14; PSMD9; PSMA8; PSMD10; UBE2C; PSMD5
APC/C:Cdc20 mediated degradation of mitotic proteins
PSMA8; ANAPC10; PSMD10; NEK2; UBE2C; PSMD5; PSMD14; PSMD9; PSME3
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
PSMD10; ANAPC10; PSME3; UBE2C; AURKB; PSMD5; PSMD9; PSMA8; PSMD14
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
PSMD14; PSMD5; PSMD9; UBE2C; PSME3; NEK2; ANAPC10; PSMA8; PSMD10
ARMS-mediated activation
NRG4; DUSP2; KIDINS220B; PAQR3A; SLC14A2; NTF7; PSMA8; PHB; CSF2; FGFR1B
AUF1 (hnRNP D0) binds and destabilizes mRNA
PSMD9; HNRNPD; EIF4G1; PSMD14; PSMD10; PSMA8; PSME3; PSMD5
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
PSMD5; PSME3; UBE2C; PSMD10; NEK2; PSMD9; PSMD14; PSMA8; ANAPC10

Protein Function

PSMD5 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD5 itself. We selected most functions PSMD5 had, and list some proteins which have the same functions with PSMD5. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein FABP3; ADCK5; LNX1; HTATIP2; DDX20; MBD1; RASSF5; IKZF1; C11orf54; EXOC3L

Interacting Protein

PSMD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD5.
PSMC2; PSMC1; TFCP2