Pla2g12b Protein, phospholipase A2, group XIIB

Pla2g12b

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Pla2g12b

Official Full Name phospholipase A2, group XIIB
Background Mouse Group XIIB secretory phospholipase A2-like protein, also knownas Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and Pla2g12b, is a secreted protein which belongs to the phospholipase A2 family. Pla2g12b / PLA2G13 is strong expression in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
Synonyms GXIIB; FKSG71; PLA2G13; GXIIIsPLA2
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PLA2G12B-1880H Recombinant Human PLA2G12B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Pla2g12b-1192M Recombinant Mouse Pla2g12b, His tagged Human Cell His
    Mouse PLA2G12B-1866MCL Recombinant Mouse PLA2G12B cell lysate Human Cell N/A
    Zebrafish PLA2G12B-12601Z Recombinant Zebrafish PLA2G12B Mammalian Cell His

    Pla2g12b involved in several pathways and played different roles in them. We selected most pathways Pla2g12b participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pla2g12b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism GPD1A; ETNK2; PGS1; LYPLA1; GPAM; PLA2G10; PLA2G12A; PCYT1AB; PNPLA7; PLA2G12B
    Ether lipid metabolism PLA2G4A; PPAP2A; GAL3ST1; PLA2G4D; PLA2G12B; LPCAT2; GAL3ST1A; PLA2G3; PPAP2CB; PLA2G12A
    Arachidonic acid metabolism AKR1C3; PLA2G2F; FAM213B; ALOX5A; PLA2G3; GGT1; CYP2C50; GPX6; FAAH2B; PLA2G4AA
    Linoleic acid metabolism CYP3A41A; PLA2G12B; CYP2C50; PLA2G4A; PLB1; PLA2G4F; CYP3A65; PLA2G2F; PLA2G4D; CYP3A25
    alpha-Linolenic acid metabolism PLA2G5; PLA2G4A; PLA2G4C; PLA2G4F; PLA2G4AA; ACOX3; PLA2G3; FADS2; PLA2G2D; PLA2G1B
    Metabolic pathways PGK2; PFKL; PIK3C2G; GMPPB; GAPDH; B4GALT3; GAL3ST1A; AUH; GOT1; GALNTL6
    Ras signaling pathway PLA2G5; TEK; CALM3; PLA2G4A; RAC1; GNGT2; PLCG2; PAK6; SOS1; BCL2L1
    Vascular smooth muscle contraction PRKCB; PLA2G4AA; AVPR1B; PRKACB; ARAF; PRKCA; MYH11; CALML3; CALD1; AVPR1A
    Pancreatic secretion KCNMA1; RHOA; CELA3B; CPA1; PRSS2; PNLIPRP1; Slc4a2; PNLIP; CTRB1; CLCA4
    Fat digestion and absorption MOGAT3; PLA2G2A; PLA2G2F; LIPF; FABP2; SCARB1; PLA2G2E; MOGAT2; PLA2G10; PNLIPRP1

    Pla2g12b has several biochemical functions, for example, calcium ion binding, metal ion binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by Pla2g12b itself. We selected most functions Pla2g12b had, and list some proteins which have the same functions with Pla2g12b. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding S100A1; MMP16; ITSN2; KCNIP3B; EYS; TTN; PCDHGA12; SULF2; PCDH1G18; PCDHA10
    metal ion binding ZFYVE26; PDE7A; DNMT3B; CYP3C4; CYP2J5; CYP2C39; CYP19A1B; ADAL; ZRANB1B; Gh
    molecular_function FNDC3BA; FAM150B; GDPD4; CRYGMXL2; BEX6; PDK3B; C1QL3B; PLAC8.1; STOX2; SFT2D2
    phospholipase A2 activity PLB1; PLA2G4A; PRDX6; PLA2G1B; PLA2G2D; PLA2G2F; RARRES3; PLA2G12B; PNPLA3; PLA2G4AA

    Pla2g12b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pla2g12b here. Most of them are supplied by our site. Hope this information will be useful for your research of Pla2g12b.

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