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RAD51L3

Official Full Name

RAD51-like 3 (S. cerevisiae)
Overview

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream ring finger and FYVE-like domain containing 1 (RFFL) gene.
Synonyms

RAD51L3; RAD51-like 3 (S. cerevisiae); DNA repair protein RAD51 homolog 4; TRAD/RAD51L3; RAD51 homolog D; RAD51-like protein 3; R51H3; Rad51d; Trad-d2; Trad-d3; Trad-d4; Trad-d6; Trad-d7; DKFZp586D0122;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	RAD51L3-13874M	Recombinant Mouse RAD51L3 Protein	Mammalian Cell	His	Inquiry
Mouse	RAD51L3-7389M-B	Recombinant Mouse RAD51L3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	RAD51L3-7389M	Recombinant Mouse RAD51L3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein

RAD51L3 involved in several pathways and played different roles in them. We selected most pathways RAD51L3 participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD51L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Homologous recombination	SYCP3;BLM;RAD54B;CDK5R2;TOP3B;RPA1;POLD1;EME1;POLD2

RAD51L3 has several biochemical functions, for example, ATP binding, DNA binding, DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD51L3 itself. We selected most functions RAD51L3 had, and list some proteins which have the same functions with RAD51L3. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DDX39B;ABCA4A;HSPA1A;CSNK2A2;PHKG2;SPATA5;RAD51L1;STRC;Acsm2a
DNA binding	POLE3;ZNF511;SMARCAD1;NFE2L2B;DMRT3;POLR2J2;ZBTB16A;KIF4A;PPARA
DNA-dependent ATPase activity	XRCC3;RAD51L3;MSH5;MSH3;SMARCAL1;DDX11;IGHMBP2;RAD51C;DHX36
double-stranded DNA binding	TP53;IFI203;XRCC5;GTF2H4;PIN4;HNRNPDL;FEN1;YBX1;HES2
contributes_to endodeoxyribonuclease activity	RAD51B;RAD51D;RAD51;RAD51L3;RAD51L1;XRCC2;ERCC4;DMC1
four-way junction DNA binding	YY1;HMGB1;RAD51L1;HMGB3;HMGB2;RAD51;RAD51L3;DMC1;MEN1
contributes_to four-way junction DNA binding	RAD51D;MSH6;XRCC3;RAD51L3;MSH2;XRCC2;RAD51C;RAD51B;RAD51L1
gamma-tubulin binding	TUBGCP2;WASH;MARK4;NDN;SPATC1;NDRG1;RAD51L3;B9D2;RAB11FIP5
nucleotide binding	RPS6KB1B;ZCRB1;TSSK5;NSFA;BMPR1BB;CPEB1A;RBM20;SRSF1A;NEK5
protein binding	ADH1A;GPSM1;TMEM194;RALYL;SCO1;ADAMTS3;GPR128;ASPSCR1;NFKBIA
recombinase activity	DMC1;RAD51C;RAD51;RBPJ;XRCC2;RAD51B;RAD51L1;RAD51L3;XRCC3
single-stranded DNA binding	HSPD1;FUBP1;PEO1;ERCC1;CSDA;TREX1;SSBP3B;NCL;HNRNPA1

RAD51L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD51L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD51L3.

XRCC2