rad51l3
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  • Official Full Name
  • RAD51-like 3 (S. cerevisiae)
  • Background
  • The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream ring finger and FYVE-like domain containing 1 (RFFL) gene.
  • Synonyms
  • RAD51L3; RAD51-like 3 (S. cerevisiae); DNA repair protein RAD51 homolog 4; TRAD/RAD51L3; RAD51 homolog D; RAD51-like protein 3; R51H3; Rad51d; Trad-d2; Trad-d3; Trad-d4; Trad-d6; Trad-d7; DKFZp586D0122
Cat.#:RAD51L3-13874MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RAD51L3 Protein
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Involved Pathway

RAD51L3 involved in several pathways and played different roles in them. We selected most pathways RAD51L3 participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD51L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Homologous recombination
RAD51B; SYCP3; POLD1; RPA2; RPA1; BLM; RAD54B; MRE11A; RAD52; SSBP1

Protein Function

RAD51L3 has several biochemical functions, for example, ATP binding, DNA binding, DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD51L3 itself. We selected most functions RAD51L3 had, and list some proteins which have the same functions with RAD51L3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein SBK3; NOLC1; ATP1A1B; FIGNL2; UBE2B; SMC6; CPS1; ACSM5; UBE2L3B; CDK10
Function DNA binding
Related Protein ZFP771; GSX1; HIST3H2A; ZNF454; KLF3; RABGAP1; RFX5; MXD4; ZFP574; ZNF789
Function DNA-dependent ATPase activity
Related Protein ERCC2; RAD51B; MSH4; MSH5; SMARCAL1; SMARCA2; RAD51D; DDX11; DMC1; CHD6
Function double-stranded DNA binding
Related Protein SAFB; HES2; PRKDC; IFI16; SETMAR; CGGBP1; TRP63; NTHL1; FBXO18; CRY1
Function contributes_to endodeoxyribonuclease activity
Related Protein RAD51D; XRCC2; RAD51L3; RAD51B; DMC1; RAD51L1; ERCC4; RAD51
Function four-way junction DNA binding
Related Protein HMGB2; HMGB1; RAD51; MEN1; HMGB3; RAD51L3; RAD51L1; DMC1; YY1
Function contributes_to four-way junction DNA binding
Related Protein RAD51B; MSH6; RAD51C; RAD51L3; RAD51D; MSH2; RAD51L1; XRCC2; XRCC3
Function gamma-tubulin binding
Related Protein PIFO; TUBGCP3; CEP57L1; BRCA2; PDE4B; MARK4; TUBGCP4; RAB11FIP5; NDN; LYN
Function nucleotide binding
Related Protein RAB34A; GKUP; CAMK2G1; UBE2D1B; KITB; MCM6L; CAMK2D1; ABCC5; ELAVL1; SMOK2B
Function protein binding
Related Protein ERCC4; ALDH3B1; TXN2; LYSMD1; ADAMTSL3; BMX; PSEN2; LCAT; PPP2R2C; MAPK1
Function recombinase activity
Related Protein RAD51C; RAD51L1; XRCC3; RBPJ; RAD51L3; XRCC2; RAD51D; RAD51; DMC1; RAD51B
Function single-stranded DNA binding
Related Protein SSBP1; PURA; LUZP4; TDP2B; PEO1; RAD51; CSDA; YBX1; RPA2; TTC6

Interacting Protein

RAD51L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD51L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD51L3.
XRCC2