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Official Full Name RAP1B, member of RAS oncogene family
Background Rap1 and Rap2 belong to the Ras subfamily of small GTPases and are activated by a wide variety of stimuli through integrins, receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCR), death domain associated receptors (DD-R) and ion channels (1
Synonyms RAP1B; RAP1B, member of RAS oncogene family; ras-related protein Rap-1b; DKFZp586H0723; K REV; RAL1B; RAS-related protein RAP1B; small GTP binding protein; GTP-binding protein smg p21B; Ras family small GTP binding protein RAP1B; K-REV; FLJ18601
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RAP1B-1127H Recombinant Human RAP1B, Member Of RAS Oncogene Family E.coli N/A
    Human RAP1B-2177H Recombinant Human RAP1B, GST-tagged E.coli GST
    Human RAP1B-2528HCL Recombinant Human RAP1B 293 Cell Lysate HEK293 N/A
    Human RAP1B-3469H Recombinant Human RAP1B, His-tagged E.coli His
    Rat RAP1B-4924R Recombinant Rat RAP1B Protein Mammalian Cell His
    Cynomolgus Monkey RAP1B-844C Recombinant Cynomolgus RAP1B Protein, His-tagged Mammalian Cell His
    Rhesus Macaque RAP1B-3785R Recombinant Rhesus monkey RAP1B Protein, His-tagged Mammalian Cell His
    Chicken RAP1B-1777C Recombinant Chicken RAP1B Mammalian Cell His
    Zebrafish RAP1B-9939Z Recombinant Zebrafish RAP1B Mammalian Cell His

    RAP1B involved in several pathways and played different roles in them. We selected most pathways RAP1B participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAP1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF8A; MEF2C; JUND; RASGRF2B; CACNA1DA; FGF20B; RAF1A; DUSP8A; TAOK1; MAP3K13
    Ras signaling pathway RAC3; GNG7; GNGT1; RAP1A; PLA2G2A; FGF20; PGF; MET; SHOC2; PRKCB
    Rap signaling pathway ANGPT1; PIK3CA; MAP2K2; HRAS; RALGDS; FGF4; MAPK1; MAPK3; VEGFB; IGF1R
    cAMP signaling pathway PDE4A; AKT2; HTR1E; BAD; PPP1CB; PLN; NFKBIA; NFKB1; CAMK2A; FFAR2
    Chemokine signaling pathway PARD3; PRKACG; CXCR4; SOS1; CXCR5; ITK; CCL21B; STAT2; PIK3R1; DOCK2
    Focal adhesion CHAD; MYL10; LAMC3; SRC; PDGFAA; ITGA1; MYL12.2; KDR; MYLPFA; PIK3CG
    Platelet activation FGB; PPP1R12A; FYN; VWF; PRKCI; GNAI2; Adcy4; PLA2G4A; PLA2G4F; FCGR2A
    Leukocyte transendothelial migration CLDN8; NCF4; NCF2; PIK3R3; CLDN17; MYLPF; PIK3CA; CXCL12; PRKCG; ITGB2L
    Long-term potentiation PPP1CC; PLCB1; ITPR3; PPP1CB; CAMK2G; PRKCA; RAF1; PPP1CA; GNAQ; GRIN2C
    Neurotrophin signaling pathway CALM3; PRKCD; PLCG1; RELA; PIK3CD; TP73; RIPK2; RPS6KA6; RPS6KA1; SH2B1
    Pancreatic secretion ATP2A1; CLCA4; KCNQ1; CTRL; PNLIPRP2; PRKCB; PLCB1; CPB2; ATP1B3; PLA2G2F
    Renal cell carcinoma PDGFB; PIK3R3; ARAF; HGF; KRAS; RAF1; FH; TCEB2; EPAS1; BRAF

    RAP1B has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by RAP1B itself. We selected most functions RAP1B had, and list some proteins which have the same functions with RAP1B. You can find most of the proteins on our site.

    Function Related Protein
    GDP binding RAB8A; ARF1; RAB9A; RAB22A; IIGP1; RALB; SRP54B; RAB17; RAP2C; RAB7L1
    GTPase activity GNG3; ARL3; GBP3; RALB; RAB10; GNB2; REM2; RABL2B; RAB14L; TUBB6
    protein binding RGS19; GYS1; HRK; CNOT1; SLC25A10; SREBF2; HSPE1; ING2; TPM1; TXNDC16
    protein complex binding GIT2; TG; KIF11; ABP1; LEPRE1; MLC1; ATP6V1B1; UGT1A6A; RNF40; PTPRF

    RAP1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAP1B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAP1B.


    Sayyah, J; Bartakova, A; et al. The Ras-related Protein, Rap1A, Mediates Thrombin-stimulated, Integrin-dependent Glioblastoma Cell Proliferation and Tumor Growth. JOURNAL OF BIOLOGICAL CHEMISTRY 289:17689-17698(2014).
    Subramanian, H; Zahedi, RP; et al. Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11:1574-1582(2013).

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