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RAP1B

  • Official Full Name

    RAP1B, member of RAS oncogene family

  • Overview

    Rap1 and Rap2 belong to the Ras subfamily of small GTPases and are activated by a wide variety of stimuli through integrins, receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCR), death domain associated receptors (DD-R) and ion channels (1
  • Synonyms

    RAP1B; RAP1B, member of RAS oncogene family; ras-related protein Rap-1b; DKFZp586H0723; K REV; RAL1B; RAS-related protein RAP1B; small GTP binding protein; GTP-binding protein smg p21B; Ras family small GTP binding protein RAP1B; K-REV; FLJ18601;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RAP1B-1127H Recombinant Human RAP1B, Member Of RAS Oncogene Family E.coli N/A
Human RAP1B-2177H Recombinant Human RAP1B, GST-tagged E.coli GST 1-184aa
Human RAP1B-3469H Recombinant Human RAP1B, His-tagged E.coli His
Human RAP1B-2528HCL Recombinant Human RAP1B 293 Cell Lysate HEK293 N/A
Human RAP1B-3979H Recombinant Human RAP1B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RAP1B-2828H Recombinant Human RAP1B protein, His-tagged E.coli His 1-184 aa
Mouse Rap1b-5372M Recombinant Mouse Rap1b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat RAP1B-4924R Recombinant Rat RAP1B Protein Mammalian Cell His
Rat RAP1B-4583R Recombinant Rat RAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RAP1B-4583R-B Recombinant Rat RAP1B Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey RAP1B-844C Recombinant Cynomolgus RAP1B Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey RAP1B-587C-B Recombinant Cynomolgus Monkey RAP1B Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey RAP1B-587C Recombinant Cynomolgus Monkey RAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RAP1B-3785R Recombinant Rhesus monkey RAP1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque RAP1B-3602R-B Recombinant Rhesus Macaque RAP1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RAP1B-3602R Recombinant Rhesus Macaque RAP1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RAP1B-9939Z Recombinant Zebrafish RAP1B Mammalian Cell His
Chicken RAP1B-1777C Recombinant Chicken RAP1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RAP1B Related Articles
  • RAP1B Related Research Area

RAP1B involved in several pathways and played different roles in them. We selected most pathways RAP1B participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAP1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayCD14;PRKACG;RAC1;PRKCBA;FGFR3;MAPK6;NRAS;MRAS;TRAF6
Ras signaling pathwayPIK3CB;NRAS;RAP1A;GAB1;PLA1A;PDGFB;PLA2G2E;PLA2G10;RASSF5
Rap signaling pathwayFGF20;RALGDS;PDGFB;NRAS;ITGB2;ITGB2L;BCAR1;THBS1;INSR
cAMP signaling pathwaySOX9;CNGA3;GNAS;CALM3;PDE4A;PTGER3;NFKB1;GABBR2;ATP1B1
Chemokine signaling pathwayCRKL;NFKBIA;CCL4;GNAI3;GRB2;CCR5;PTK2;CXCR4;PF4V1
Focal adhesionRAF1B;PPP1CA;MYL12B;ITGA4;SPP1;KDRL;ZYX;RAC1;RAC1A
Platelet activationMAPK1;PLCG2;P2RY1;PLA2G4F;PRKCZ;GNAQ;RAP1B;FGA;ARHGAP35
Leukocyte transendothelial migrationPRKCA;MAPK11;MYL12B;CLDN14;ACTG1;PTK2;VASP;CLDN1;RAP1B
Long-term potentiationGRIA1;PPP3CC;PRKCB;PRKACA;PPP3R1;ITPR3;PRKACG;CAMK2B;PLCB3
Neurotrophin signaling pathwayBAX;NFKBIB;PSEN2;SHC2;RPS6KA2;AKT2;PIK3CB;SORT1;PRKCD
Pancreatic secretionCLCA5;Car2;ATP1B2;TPCN2;PRSS3;RHOA;ATP1A2;CLCA1;CPB2
Renal cell carcinomaHIF1A;MAPK3;NRAS;EPAS1;TGFB2;EGLN2;PAK7;FH1;MET

RAP1B has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAP1B itself. We selected most functions RAP1B had, and list some proteins which have the same functions with RAP1B. You can find most of the proteins on our site.

Function Related Protein
GDP bindingRAB18;ARL2;RAB7L1;RAB9A;RRAS;GEM;GNAI1;ARL8B;RAB12
GTP bindingGNA13B;GBP2;ADSSL;EEF1A1L2;GNAO1B;SEPT4;RHOV;RTKN;GCH2
GTPase activityEIF2S3;RAB12;DNAJC27;RAB1BB;GTPBP1;LSG1;RHOJ;DNM1A;MFN2
protein bindingNSL1;FGFR3;HAND2;MAGEB2;GSS;LAPTM4B;LRRC75A-AS1;CCL4;DNAAF2
protein complex bindingCEBPA;AP2A1;WASF2;RRAS;AKAP5;FBLN1;MTAP1B;NFYB;ING2

RAP1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAP1B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAP1B.

RALGDS; RASSF5; VCAM1; UBC; RAP1GAP; RAPGEF3; MCC; PAK2; MAP3K14; SMURF2; RGL2

Sayyah, J; Bartakova, A; et al. The Ras-related Protein, Rap1A, Mediates Thrombin-stimulated, Integrin-dependent Glioblastoma Cell Proliferation and Tumor Growth. JOURNAL OF BIOLOGICAL CHEMISTRY 289:17689-17698(2014).
Subramanian, H; Zahedi, RP; et al. Phosphorylation of CalDAG-GEFI by protein kinase A prevents Rap1b activation. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11:1574-1582(2013).
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