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RIPK4

Official Full Name

receptor-interacting serine-threonine kinase 4
Overview

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
Synonyms

RIPK4; receptor-interacting serine-threonine kinase 4; ANKRD3, ankyrin repeat domain 3; receptor-interacting serine/threonine-protein kinase 4; ANKK2; DIK; PKC delta interacting protein kinase; PKK; protein kinase C associated kinase; RIP4; protein kinas;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RIPK4-5925H	Recombinant Human RIPK4 Protein (Phe22-Ile286), N-GST tagged	E.coli	N-GST	Phe22-Ile286	Inquiry
Mouse	RIPK4-14246M	Recombinant Mouse RIPK4 Protein	Mammalian Cell	His		Inquiry
Mouse	RIPK4-7617M	Recombinant Mouse RIPK4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	RIPK4-7617M-B	Recombinant Mouse RIPK4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	RIPK4-12307Z	Recombinant Zebrafish RIPK4	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RIPK4 Related Articles

RIPK4 involved in several pathways and played different roles in them. We selected most pathways RIPK4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RIPK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RIPK4 has several biochemical functions, for example, ATP binding, kinase activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RIPK4 itself. We selected most functions RIPK4 had, and list some proteins which have the same functions with RIPK4. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	ATP9B;STK24B;GM711;NSFA;DDX18;AK1;DDX52;SRPK2;MAP3K2
kinase activity	PANK1A;TAB3;cka1;Fert2;KALRN;PRKRIRA;STK24B;CAMK2D1;HIPK2
nucleotide binding	ATP8A1;PABPC3;POLDIP3;SRSF1;NT5C1B;ATP1A2A;NT5E;PPARGC1B;PLK2B
protein binding	C14orf159;NR1H2;ACHE;BRD9;GIMAP5;TMEM93;SLC22A17;MAZ;ST8SIA5
protein kinase activity	PAK4;WNK2;PIK3R4;STK3;MAPK14A;STK38A;GC2;NTRK2B;CDC7
protein serine/threonine kinase activity	CSNK1G1;GRK5;MAP4K6;GM711;PRKDC;BMPR2A;RPS6KA3B;TRIO;SBK1
transferase activity	PNP6;PRKACBB;FUT9D;NDUFAF6;KITA;HHATLA;STK24B;UGT1A7C;TAOK3

RIPK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RIPK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RIPK4.

TRAF7; Pgls

Leslie, EJ; O'Sullivan, J; et al. Expanding the Genetic and Phenotypic Spectrum of Popliteal Pterygium Disorders. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 167A:545-552(2015).

Heim, D; Cornils, K; et al. Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis. ONCOGENE 34:385-393(2015).