|Official Full Name||ring finger protein 138, E3 ubiquitin protein ligase|
|Background||The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed.|
|Synonyms||RNF138; ring finger protein 138, E3 ubiquitin protein ligase; ring finger protein 138; E3 ubiquitin-protein ligase RNF138; STRIN; NLK-associated RING finger protein; Nemo-like kinase-associated RING finger protein; NARF; HSD-4; hNARF; MGC8758|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
RNF138 involved in several pathways and played different roles in them. We selected most pathways RNF138 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF138 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||CLEC2G; LRSAM1; UFL1; UBR2; ATG7; RAP1GAP2; TRIM11; SIGLEC6; LILRB2; KIF2C|
|Antigen processing: Ubiquitination &||TRAF7; KLHL20; HECTD3; TPP2; UBE2L6; TRIM50; RNF138; LTN1; KLHL21; UBE2J2|
|Proteasome degradation||SPSB2; CMTM2A; RNF41; LTN1; ASB8; UBE2J2; FBXO3; TPP2; LRSAM1; FBXO27|
|Class I MHC mediated antigen processing &||CTSL2; RNF220; PJA1; UBR2; TRIM50; ATG7; ASB14; CD207; MKRN1; ASB9|
|presentation||RNF34; ERAP1; SEC23A; ERAP2; CTSS; SPSB4; ASB13; CMTM2A; UBE2V2; UBE2E3|
|Immune System||CYLD; CLEC5A; SIGLEC15; PJA2; CD200R1; SUGT1; KIF18A; IGHM; CD200; SRMS|
RNF138 has several biochemical functions, for example, ligase activity, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF138 itself. We selected most functions RNF138 had, and list some proteins which have the same functions with RNF138. You can find most of the proteins on our site.
|ligase activity||RNF14; TRIM58; RNF34; RNF2; TRIM33; RNF38; TRIM56; MARCH11; SYVN1; NAPRT1|
|protein binding||MBD1; MLF2; TNFRSF11A; TMEM182; Akap3; DEDD; PEG10; FHL3; C7orf42; ARHGAP4|
|protein kinase binding||TENC1; PDGFRB; KIF20A; FBXO7; PTEN; TBC1D14; MS4A2; RHEB; CCNB3; TRIB3|
|zinc ion binding||TRIM101; BBOX1; CRIP3; ZBBX; NANOS3; ADH8B; ZCCHC17; COP1; RASGRP1; SP140L|
RNF138 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF138 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF138.
UBE2K; HIP2; PCBP4; UBE2D2; TAF9; C6orf165; LNX2; UBE2W; QKI; TRIM8; UBE2D4; SLX4