rragb
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  • Official Full Name
  • Ras-related GTP binding B
  • Background
  • The mTORC1 kinase complex is a critical regulator of cell growth. Its activity is modulated by energy levels, growth factors, and amino acids via signaling through Akt, MAPK, and AMPK pathways. Recent studies found that the four related GTPases, RagA, Rag
  • Synonyms
  • RRAGB; Ras-related GTP binding B; ras-related GTP-binding protein B; rag B; GTP-binding protein ragB; RAGB; bA465E19.1
Cat.#:RRAGB-2441HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RRAGB, His-tagged
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Cat.#:RRAGB-14516MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RRAGB Protein
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Cat.#:RRAGB-5179RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RRAGB Protein
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Cat.#:RRAGB-4034RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RRAGB Protein, His-tagged
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Cat.#:RRAGB-2147HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RRAGB 293 Cell Lysate
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Involved Pathway

RRAGB involved in several pathways and played different roles in them. We selected most pathways RRAGB participated on our site, such as Cellular responses to stress, Energy dependent regulation of mTOR by LKB1-AMPK, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with RRAGB were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular responses to stress
ATG4A; HIST2H3C; DNAJC7; EEF1A1; HIST1H1B; HSBP1; CBX6; DPF1; CHMP4B; DYNLL2B
Energy dependent regulation of mTOR by LKB1-AMPK
LAMTOR1; HBXIP; C7orf59; RRAGB; RRAGA
Gene Expression
TP53RK; COX7C; EIF1AXA; PHF1; ZNF792; ZNF649; HENMT1; RNPC3; ZNF254; JARID2
Generic Transcription Pathway
ZNF563; ZNF718; ZNF554; MED26; ZNF225; ZNF324; TUBB3; ZNF394; ESRRGA; RRAGB
IGF1R signaling cascade
C7orf59; EIF4B; IGF2B; RRAGB; RRAGA; HBXIP; LAMTOR1
IRS-mediated signalling
HBXIP; LAMTOR1; C7orf59; RRAGB; RRAGA
IRS-related events triggered by IGF1R
RRAGA; RRAGB; IGF2B; LAMTOR1; HBXIP; C7orf59
Insulin receptor signalling cascade
RRAGA; C7orf59; GRB10; GRB10A; LAMTOR1; RRAGB

Protein Function

RRAGB has several biochemical functions, for example, GTP binding, GTPase activity, guanyl ribonucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RRAGB itself. We selected most functions RRAGB had, and list some proteins which have the same functions with RRAGB. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein RRAS2; NPR2; EEF2; RAB2A; GNAT2; TUBA1C; RAC1A; RABL6; SEPT12; RAP2AB
Function GTPase activity
Related Protein EEF2A.1; RAB1A; RND2; GTPBP3; DNM1L; GTPBP10; RHOQ; ARF5; ARF1; EEF1A1A
Function guanyl ribonucleotide binding
Related Protein RRAGB
Function protein binding
Related Protein SLC7A1; NAA10; TRIP6; C18orf1; UTP11L; MOAP1; ITGB3; HP1BP3; ECT2; TNS3

Interacting Protein

RRAGB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RRAGB here. Most of them are supplied by our site. Hope this information will be useful for your research of RRAGB.
RRAGC; RRAGD; LAMTOR1; LAMTOR3

RRAGB Related Articles

Oloumi, A; Lam, W; et al. Identification of genes differentially expressed in V79 cells grown as multicell spheroids. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 78:483-492(2002).
Tsuda, T; Kusui, T; et al. Neuromedin B receptor activation causes tyrosine phosphorylation of p125(FAK) by a phospholipase C independent mechanism which requires p21(rho) and integrity of the actin cytoskeleton. BIOCHEMISTRY 36:16328-16337(1997).