rras2
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  • Official Full Name
  • related RAS viral (r-ras) oncogene homolog 2
  • Background
  • This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.
  • Synonyms
  • RRAS2; related RAS viral (r-ras) oncogene homolog 2; ras-related protein R-Ras2; TC21; ras-like protein TC21; teratocarcinoma oncogene
Cat.#:RRAS2-1962HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human RRAS2 Protein, MYC/DDK-tagged
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Cat.#:RRAS2-1402HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Related RAS Viral (r-ras) Oncogene Homolog 2, His-tagged
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Cat.#:RRAS2-2443HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RRAS2, GST-tagged
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Cat.#:RRAS2-29988THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RRAS2, His-tagged
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Cat.#:RRAS2-30472THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RRAS2
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Cat.#:RRAS2-14520MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RRAS2 Protein
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Cat.#:RRAS2-4035RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RRAS2 Protein, His-tagged
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Cat.#:RRAS2-1605CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RRAS2
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Cat.#:RRAS2-2546ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RRAS2
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Cat.#:RRAS2-1544HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RRAS2 cell lysate
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Involved Pathway

RRAS2 involved in several pathways and played different roles in them. We selected most pathways RRAS2 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RRAS2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PPM1B; MAPK14A; PPP3CCB; LAMTOR3; RAC3A; CACNA1BA; PDGFA; ZAK; FGF11A; FGF5
Ras signaling pathway
MRAS; PLA2G6; MAPK3; KLK1B4; RGL2; Fgf15; EFNA4; FGF10; MAPK1; RASAL1
cAMP signaling pathway
GRIN1; FXYD2; AKT2; PIK3CG; NFATC1; GRIN3B; GABBR2; RAC1; PPP1CB; MAP2K1
Phospholipase D signaling pathway
GRB2; GNA12; PRKCA; PPAP2C; PLCG1; GRM5; PLCB4; CYTH2; LPAR3; GRM2
Tight junction
CLDN8; SHROOM4; CLDN10; CLDN11; MYL5; GNAI2B; CASKB; AKT1; MYH15; HRASB
Regulation of actin cytoskeleton
PPP1CB; SCINLA; PDGFRB; ABI2; SSH2; FGF10; NRAS; MYL10; MAP2K2B; ITGB8
HTLV-I infection
PRKACB; POLE3; PPP3R2; SFPI1; CRTC1; FZD6; ETS2; HLA-F; FZD1; TLN1
Proteoglycans in cancer
WNT8A; FZD9; FZD6; RPS6KB1; ITGB3; CBLB; PTK2; ITPR1; TGFB1; ERBB3

Protein Function

RRAS2 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RRAS2 itself. We selected most functions RRAS2 had, and list some proteins which have the same functions with RRAS2. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein RAB11BB; ARL13B; GIMAP2; RASD2; RAB3AB; RAB3AA; RAB2B; NKIRAS1; ASCL1B; SEPT3
Function GTPase activity
Related Protein RAB30; GIMAP7; EFTUD2; ARF3; GNG11; TUBA1L2; GSPT1L; DNAJC27; GNA12A; GNA11A
Function protein binding
Related Protein MED4; BOP1; PTI; PSG1; CDCA7L; CCDC148; TMEM66; NDE1; IGFN1; MBD4

Interacting Protein

RRAS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RRAS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RRAS2.
Fnta; RIN1; Tubb4b; Trim69; CREB3; RAF1; ARAF; XRCC6; LGALS4; TRAF2; RALGDS; Rassf5