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SEC23IP

Official Full Name

SEC23 interacting protein
Overview

This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene.
Synonyms

SEC23IP; SEC23 interacting protein; SEC23-interacting protein; P125; MSTP053; Phospholipase; Sec23 interacting protein p125; OTTHUMP00000020613; P125A;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SEC23IP-2564H	Recombinant Human SEC23IP, GST-tagged	E.coli	GST	C-350aa	$319 / 25ug
Human	SEC23IP-1992HCL	Recombinant Human SEC23IP 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	Sec23ip-5746M	Recombinant Mouse Sec23ip Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	SEC23IP-4711Z	Recombinant Zebrafish SEC23IP	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SEC23IP Related Articles

SEC23IP involved in several pathways and played different roles in them. We selected most pathways SEC23IP participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC23IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Asparagine N-linked glycosylation	ST3GAL3A;NSFA;STT3A;NANP;CTSZ;NAPAB;TRAPPC10;MPDU1;SERPINA1L
COPII (Coat Protein 2) Mediated Vesicle Transport	YKT6;SEC23A;SEC22A;LMAN2;NSFA;TRAPPC1;SEC24A;TFG;GORASP1
ER to Golgi Anterograde Transport	TRAPPC6BL;ANKRD28;NAPAB;NSFB;TRAPPC6A;SEC24A;TRAPPC6B;TRAPPC10;YKT6
Membrane Trafficking	CNO;MYO6B;NSFA;GJA5;COPZ1;SEC22A;ANKRD28;TPD52L1;SEC23IP
Metabolism of proteins	ADD1;NAT8B;KLHDC3;IGFBP2B;SSPO;EXOC5;TRAPPC2L;TOMM7;HDGF
Post-translational protein modification	SEC22A;MUC4;UBA2;WDR85;TMED2;TRAPPC1;ADAMTS3;EIF5A;ST6GALNAC1.2
Transport to the Golgi and subsequent modification	BET1;YKT6;PPP6R3;CNIH;CTAGE5;SEC23IP;TRAPPC2;SEC22A;PPP6C
Vesicle-mediated transport	GAK;TRAPPC6B;TRAPPC3;CLVS1;TBC1D8B;CLINT1;RALAB;RALAA;SNX9A

SEC23IP has several biochemical functions, for example, metal ion binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC23IP itself. We selected most functions SEC23IP had, and list some proteins which have the same functions with SEC23IP. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	OSR1;WDFY3;ZFP161;SDHDA;TAX1BP1;MOCS3;ZFP609;RBAK;TPH1A
poly(A) RNA binding	RBM25;TBL3;ALG13;NOSIP;EIF2S1B;CAPRIN1;RPS14;HMGB2;MRPL37
protein binding	RAB9A;ZNF41;ZFP335;ZFYVE9;ZWINT;WDR83;LUC7L2;SALL2;RNASE1

SEC23IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC23IP here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC23IP.

SSC5D; HSPB11; PDCD6; Sec24c; Kif4; PRKD2; Vps28; TIMM13

de Barsy, M; Mirabella, A; et al. A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells. MICROBIOLOGY-SGM 158:2610-2618(2012).