SETD1B Protein, SET domain containing 1B


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Official Full Name SET domain containing 1B
Background SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al.,;2007 (PubMed 17355966)).
Synonyms SETD1B; SET domain containing 1B; histone-lysine N-methyltransferase SETD1B; KIAA1076; KMT2G; Set1B; hSET1B; lysine N-methyltransferase 2G; SET domain-containing protein 1B; FLJ20803
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • GST
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SETD1B-185H Recombinant Human SET1B Complex Protein, His/GST-tagged E.coli His/GST
    Mouse SETD1B-14978M Recombinant Mouse SETD1B Protein Mammalian Cell His
    Chicken SETD1B-2366C Recombinant Chicken SETD1B Mammalian Cell His

    SETD1B involved in several pathways and played different roles in them. We selected most pathways SETD1B participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Lysine degradation SETDB2; COLGALT2; SETDB1B; C2orf34; WBP7; GCDH; SETMAR; EHMT1; NSD1; HYKK.2

    SETD1B has several biochemical functions, for example, RNA binding, histone-lysine N-methyltransferase activity, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD1B itself. We selected most functions SETD1B had, and list some proteins which have the same functions with SETD1B. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding RPL29; AGO1; HDLBPA; UBR5; EXOSC9; SF3A1; RPS15A; METTL3; RNASEL2; DHX36
    histone-lysine N-methyltransferase activity SMYD2A; EHMT2; EZH2; WBP7; MLL5; DOT1L; SETD7; KMT2A; SETDB1A; MLL1
    methyltransferase activity TOMT; SUV39H1A; ALDH1L2; PRDM1; KMT2A; Mettl11b; GAMT; SMYD5; PRMT1; SETDB1B
    molecular_function PSMD11A; TMEM35; SLC15A5; GM14434; TMEM229A; PCDHGA4; MBLAC2; WDR5B; MFSD6B; MVB12BA
    nucleic acid binding ZBTB20; GLI2B; N6AMT1; KLF12A; ZCCHC13; RNASEH1; BCL6AB; RNASE11; IMPDH1; EIF4A1B
    nucleotide binding CRY1; GRK1B; POLR2D; UBE2D1B; NT5C3A; ATAD1A; MXA; PDXK; RHOGD; SREK1
    transferase activity SAT1A.2; SULT6B1; CD38; UGT1B3; DGAT1A; GBGT1L3; GNPTAB; UGT1B7; HS3ST3B1A; CSNK2A2A

    SETD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD1B.

    Qadota, H; McGaha, LA; et al. A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (obscurin) in Caenorhabditis elegans. MOLECULAR BIOLOGY OF THE CELL 19:2424-2432(2008).
    Wu, H; Zhang, GY; et al. T cell lines specific for a synthetic Heymann nephritis peptide derived from the receptor-associated protein. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 121:157-164(2000).

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