SHC4 Protein, SHC (Src homology 2 domain containing) family, member 4


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Official Full Name SHC (Src homology 2 domain containing) family, member 4
Synonyms SHC4; SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4; rai like protein; RaLP; hShcD; MGC34023; SH2 domain protein C4; SHC (Src homology 2 domain containing) family member 4; SHC 4; SHC; SHC family member 4; SHC transforming protein 4; SHC transforming protein D; SHCD; Src homology 2 domain containing familymember 4; Src homology 2 domain containing transforming protein C4; rai-like protein; OTTHUMP00000162250; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SHC4-1861HCL Recombinant Human SHC4 293 Cell Lysate HEK293 N/A
    Human SHC4-2656H Recombinant Human SHC4, GST-tagged E.coli GST
    Mouse SHC4-15093M Recombinant Mouse SHC4 Protein Mammalian Cell His

    SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway ERBB3B; PIK3CB; PAK2; BTC; MAP2K4B; PIK3CG; HBEGFB; MAP2K2A; CAMK2B1; NCK2A
    Ras signaling pathway RASAL3; NGFR; PIK3CD; FGF20; FGFR1; CALML5; RASSF1; RAF1; CALML3; FGFR2
    Chemokine signaling pathway CCL23; GNB4; GNAI2; IKBKG; PLCB4; PIK3CD; CCL14; ROCK1; CCL2; CCL4L2
    Phospholipase D signaling pathway TSC1; PPAP2C; RHOA; PPAP2A; GRM5; CYTH1; MAP2K2; AGPAT3; PPAP2B; PIP5K1A
    Focal adhesion IGF1RA; XIAP; COL4A1; MYL2B; MYL12.2; HRASB; LAMB3; MYLPFB; PTEN; ITGA9
    Natural killer cell mediated cytotoxicity SHC4; NCR1; IFNA4; NFATC2; TNFSF10; RAET1G; FCGR4; GM-CSF; KIR2DL4; MAP2K1
    Neurotrophin signaling pathway NGFR; BAD; PIK3CB; KIDINS220; CALM4; SH2B1; NFKBIA; CDC42; MAP2K2; MAGED1
    Insulin signaling pathway HK1; PIK3CD; PYGMA; MTOR; PRKAR2A; FBP2; CALM1B; G6PC; IRS4; IRS2
    Estrogen signaling pathway SHC1; GPR30; MAP2K2; CALML3; PLCB4; SRC; PRKACA; CREB3L2; CALM2; AKT2
    Prolactin signaling pathway PIK3CG; LHB; FOXO3; SHC2; PIK3R2; STAT5A; SRC; SHC1; CCND1; MAPK9
    Bacterial invasion of epithelial cells MET; SEPT6; SHC3; ACTG1; WASF1; WAS; SEPT11; SEPT12; CTNNA1; SHC2
    MicroRNAs in cancer MAPK1; NOTCH2; APC2; CDC25C; Abcb1b; SLC45A3; CYP24A1; FZD3; PRKCG; MCL1
    Glioma SHC2; PLCG1; TP53; NRAS; RAF1; HRAS; BRAF; MAP2K2; IGF1R; SHC4
    Chronic myeloid leukemia IKBKB; TGFB1; ARAF; NFKBIA; RB1; BCL2L1; BRAF; CTBP2; MAPK3; BCR

    SHC4 has several biochemical functions, for example, protein binding, protein domain specific binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding INO80B; SUV39H2; PBX2; ATRIP; C17orf62; FAM162A; PRKDC; COPS8; ARFRP1; RAD9A
    protein domain specific binding KPNB1; NFE2L2; DRD3; XPA; EFS; ITGA3; HIST1H4L; HMGB2; HIST1H4D; WNT5A
    protein kinase binding CCNB3; SPDYA; CDK5; LCK; CDKN2B; FGR; FGF19; MS4A2; BAG5; PGAM1
    receptor tyrosine kinase binding FIZ1; PTPN11; PCNA; ANXA5; LRP4; TRP53; CPNE3; TP53; ANGPT1; SOCS5

    SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.


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