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SHC4

  • Official Full Name

    SHC (Src homology 2 domain containing) family, member 4

  • Synonyms

    SHC4; SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4; rai like protein; RaLP; hShcD; MGC34023; SH2 domain protein C4; SHC (Src homology 2 domain containing) family member 4; SHC 4; SHC; SHC family member 4; SHC transforming protein 4; SHC transforming protein D; SHCD; Src homology 2 domain containing familymember 4; Src homology 2 domain containing transforming protein C4; rai-like protein; OTTHUMP00000162250; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SHC4-2656H Recombinant Human SHC4, GST-tagged E.coli GST C-term-307aa
Human SHC4-1861HCL Recombinant Human SHC4 293 Cell Lysate HEK293 N/A
Human SHC4-355H Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Mouse SHC4-15093M Recombinant Mouse SHC4 Protein Mammalian Cell His
Mouse Shc4-5855M Recombinant Mouse Shc4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SHC4-8144M Recombinant Mouse SHC4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SHC4-8144M-B Recombinant Mouse SHC4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SHC4 Related Signal Pathway

SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayERBB3;NRG1;AREGB;HRASA;PIK3R5;MAPK1;MYCB;RPS6KB1B;GRB2A
Ras signaling pathwayKLK1B4;VEGFC;CALM1;PGF;RAP1A;TBK1;PLA2G5;GAB1;RALGDS
Chemokine signaling pathwayNFKB1;CCL28;SHC4;CXCL12;Ccl21c;LOC100033925;GNG12;PF4V1;CCL4L2
Phospholipase D signaling pathwayCXCR2;FCER1A;RRAS2;PIK3CA;LPAR5;AVP;PLCG2;FCER1G;LPAR2
Focal adhesionITGB6;LAMB1A;BAD;RAP1B;PDGFRA;ITGA6B;THBS4A;PIK3R3B;ITGA7
Natural killer cell mediated cytotoxicityIFNGR2;IFNA13;TNFSF10;MAPK1;SH3BP2;RAET1E;PIK3R2;IFNG;VAV1
Neurotrophin signaling pathwayIRAK1;PIK3CA;PIK3CG;CAMK4;PTPN11;NRAS;RIPK2;TRAF6;PSEN1
Insulin signaling pathwayPPP1R3D;PHKA2;PRKAR1A;PHKB;CALM3B;PRKAR2B;RAF1A;EIF4E2RS1;PYGB
Estrogen signaling pathwayPRKACG;HSP90AB1;CALM1;CREB3L2;NOS3;ATF4;PRKACA;HRAS;PIK3R2
Prolactin signaling pathwaySHC2;PIK3R5;IRF1;SIRPA;MAPK9;GSK3B;TH;MAPK3;PIK3R3
AlcoholismGNAI2;NTRK2;HIST3H2BB;CRH;HIST2H3C1;FOSB;PDYN;HIST1H2AF;DRD1
Bacterial invasion of epithelial cellsCLTA;PIK3CA;SEPT2;SHC3;PIK3CG;CBLC;CD2AP;CAV3;WASF2
MicroRNAs in cancerTTC6;IKBKB;RPTOR;CDCA5;SOX4;IRS2;ST14;PTEN;ABCB1
GliomaSHC1;PIK3CA;CAMK2A;SHC2;TGFA;NRAS;HRAS;PRKCB;TRP53
Chronic myeloid leukemiaRAF1;BCL2L1;SHC3;MECOM;CDK6;ABL1;PTPN11;SHC2;SOS1

SHC4 has several biochemical functions, for example, protein binding, protein domain specific binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

Function Related Protein
protein bindingHIF1AN;CD163;SGTA;IRAK1;ARHGEF3;UQCRC2;KRT14;ATF5;LZTS1
protein domain specific bindingAKAP1;AIDA;CALM;GABRR2;ST13;ARHGEF4;XPO1;ATP1A1;HIST1H4N
protein kinase bindingSQSTM1;FGR;SV2A;BCAR1;PRKAG3;BORA;CDC42;SPAG16;CCNA2
receptor tyrosine kinase bindingANGPT4;SQSTM1;NRG1;FIZ1;NRG3;ARHGEF16;PCNA;DNAJA3;PIK3R2

SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.

EGFR; MET; AR; KIT

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