slc12a4
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  • Official Full Name
  • solute carrier family 12 (potassium/chloride transporters), member 4
  • Background
  • Potassium-chloride transporter, member 4 is a chloride potassium symporter. It is encoded by the gene SLC12A4.
  • Synonyms
  • SLC12A4; solute carrier family 12 (potassium/chloride transporters), member 4; solute carrier family 12 member 4; KCC1; Electroneutral potassium chloride cotransporter 1; Erythroid K Cl cotransporter 1; FLJ40489; hKCC 1; hKCC1; KCC 1; Potassium transport protein; Potassium/chloride cotransporter 1; Solute carrier family 12 (potassium/chloride transporters) member 4; K-Cl cotransporter; OTTHUMP00000174837; erythroid K:Cl cotransporter; erythroid K-Cl cotransporter 1; electroneutral potassium-chloride cotransporter 1
Cat.#:SLC12A4-2698HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC12A4, His-tagged
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Cat.#:SLC12A4-5425RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SLC12A4 Protein
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Cat.#:SLC12A4-1806HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SLC12A4 293 Cell Lysate
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Involved Pathway

SLC12A4 involved in several pathways and played different roles in them. We selected most pathways SLC12A4 participated on our site, such as Cation-coupled Chloride cotransporters, SLC-mediated transmembrane transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC12A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cation-coupled Chloride cotransporters
SLC12A7; SLC12A3; SLC12A4; SLC12A1; SLC12A5B
SLC-mediated transmembrane transport
APOD; SLC35B2; SLC20A2; SLC1A7A; SLC29A4; SLC5A3A; SLC24A4A; SLC34A2A; SLC30A5; MATE4
Transmembrane transport of small molecules
EPB49; SLC22A12; AQP10A; TTYH2; TPCN1; SLC20A1A; CCC2; FXYD6-FXYD2; SLC1A2B; SLC29A3
Transport of inorganic cations/anions and amino acids/oligopeptides
SLC6A20A; SLC9A7; SLC9A3.2; SLC4A2B; SLC7A11; SLC7A3; SLC12A4; SLC43A1A; SLC26A7; SLC15A1B

Protein Function

SLC12A4 has several biochemical functions, for example, potassium ion symporter activity, potassium:chloride symporter activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC12A4 itself. We selected most functions SLC12A4 had, and list some proteins which have the same functions with SLC12A4. You can find most of the proteins on our site.
Function
Related Protein
Function potassium ion symporter activity
Related Protein SLC12A10.1; SLC12A10.3; SLC12A10.2; SLC12A2; SLC12A1; SLC12A7; SLC12A8; SLC12A5; SLC12A5B; SLC12A4
Function potassium:chloride symporter activity
Related Protein SLC12A1; SLC12A7; SLC12A5B; SLC12A8; SLC12A5; SLC12A10.1; SLC12A10.3; SLC12A2; SLC12A4; SLC12A10.2
Function protein kinase binding
Related Protein CAV1; TBC1D14; DNM1; KIF20A; PRKAG2; ACVRL1; MAP2K6; ADRA2A; CDC25C; MVP

Interacting Protein

SLC12A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC12A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC12A4.
ATF7IP