slc9a1
Share
  • Official Full Name
  • solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
  • Background
  • SLC9A1 (NHE1), a member of the Na+/H+ exchanger family, is a ubiquitous membrane protein that regulates intracellular pH and cell volume. Furthermore, SLC9A1 is known to interact with the actin cytoskeleton. Fibroblasts expressing mutated NHE1 that fails
  • Synonyms
  • SLC9A1; solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1; APNH, NHE1, solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) , solute carrier family 9 (sodium/hydrogen ex
Cat.#:SLC9A1-5584RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SLC9A1 Protein
+Inquiry
Cat.#:SLC9A1-3435CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SLC9A1
+Inquiry
Cat.#:SLC9A1-6293ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SLC9A1
+Inquiry
Cat.#:SLC9A1-1695HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SLC9A1 293 Cell Lysate
+Inquiry

Involved Pathway

SLC9A1 involved in several pathways and played different roles in them. We selected most pathways SLC9A1 participated on our site, such as cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC9A1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cAMP signaling pathway
PIK3R1; GRIN2C; FSHB; GRIA3; EP300; LOC100328615; GNAI3; RELA; BDNF; PIK3CG
Cardiac muscle contraction
CACNG6; SLC9A1; TPM4A; ATP1B1; ATP1A1A.1; CACNG3; SLC8A1; COX5AA; TPM1; CACNG2
Adrenergic signaling in cardiomyocytes
CACNB2; ADCY1A; SLC8A1; CALM2; ACTC1; PPP2R3C; ATP1A4; CACNG2A; CACNA2D4; PIK3CG
Regulation of actin cytoskeleton
KRAS; ACTN4; FGFR2; FGF18; PTK2AB; FGF20B; ITGA7; FN1A; RRAS2; CDC42
Thyroid hormone signaling pathway
TBC1D4; SLC9A1; GSK3B; SRC; PRKCG; RXRG; NRAS; MED4; PIK3CG; FXYD2
Salivary secretion
ATP1A1; ATP1A3; PRH2; PLCB4; Adcy4; GUCY1B3; AQP5; PRKACG; CST4; PRB1
Gastric acid secretion
MYLK; GNAI2; ACTB; EZR; SLC9A1; PLCB1; CAMK2A; MYLK3; ATP4B; MYLK2
Pancreatic secretion
ATP2A3; Car2; FXYD2; PLCB3; CELA3B; TRPC1; CELA2B; KCNMA1; PRSS2; PRKCA
Bile secretion
AQP4; ABCG8; Adcy4; SLC10A1; ATP1B4; SLC22A1; ATP1A4; ATP1B3; PRKACB; CYP3A4
Proteoglycans in cancer
MTOR; TLR4; SOS1; TNF; ARHGEF12; VEGFA; FZD1; WNT8A; HOXD10; BRAF

Protein Function

SLC9A1 has several biochemical functions, for example, calcium-dependent protein binding, calmodulin binding, phosphatidylinositol-4,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC9A1 itself. We selected most functions SLC9A1 had, and list some proteins which have the same functions with SLC9A1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium-dependent protein binding
Related Protein MASP2; CCDC167; MMP13; ANXA7; MYO5A; SYT1; STX1A; S100P; ALG2; MYO1D
Function calmodulin binding
Related Protein KCNN3; CAMK1G; SLC14A2; RRAD; CAMK1D; CAMK1GB; MYO9B; MAPKAPK2B; MYO1F; ASPM
Function phosphatidylinositol-4,5-bisphosphate binding
Related Protein PFN1; SYTL2; MAPKAP1; Apba1; KCNJ2; ADAP2; MYO1G; ANXA8; PARD3; KRIT1
Function protein binding
Related Protein KIAA1274; CYHR1; OTX1; WDFY3; EIF4EA; TBC1D1; GTF3C6; SNRPN; KRTAP10-5; RASAL2
Function protein binding, bridging
Related Protein ST13; FSCN2B; SH2D1B; NEFL; VPS18; MMS19; CNKSR1; TRIM22; FLRT3; TRIM17
Function protein complex scaffold
Related Protein SMARCD1; TELO2; SLC9A3R2; SLC9A3R1; MAP2K2; MAGI1; ARRB2; DISC1; MAGI1B; ISCU
Function protein phosphatase 2B binding
Related Protein SLC9A1; SOD1; PPP3CB; MYOZ2; AKAP5; ATP2B4; BAD; AKAP1
Function sodium:proton antiporter activity
Related Protein SLC9A6B; SLC9A3.2; SLC9A7; SLC9A4; SLC9A5; SLC9A9; SLC9A3; SLC9A6A; SLC9A8; SLC9A1
Function sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential
Related Protein SLC9A1
Function solute:proton antiporter activity
Related Protein SLC9A5; SLC9A9; TMCO3; SLC9A6B; SLC9A3.1; SLC9A4; SLC9A3.2; NHEDC1; SLC9A1; SLC9A10

Interacting Protein

SLC9A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC9A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC9A1.
YWHAB; MAP3K7; CHP2; MAP4K4; UBE2I; MDFI; Rab5c; YWHAZ; Gbf1; Taf15; AP4S1; Mad2l1