smc4
Share
  • Official Full Name
  • structural maintenance of chromosomes 4
  • Background
  • Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi
  • Synonyms
  • SMC4; structural maintenance of chromosomes 4; SMC4 (structural maintenance of chromosomes 4, yeast) like 1 , SMC4 structural maintenance of chromosomes 4 like 1 (yeast) , SMC4L1; structural maintenance of chromosomes protein 4; CAP C; hCAP C; SMC protein 4; XCAP-C homolog; chromosome-associated polypeptide C; SMC4 structural maintenance of chromosomes 4-like 1; CAPC; CAP-C; SMC-4; SMC4L1; hCAP-C
Cat.#:SMC4-2811HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMC4, GST-tagged
+Inquiry
Cat.#:SMC4-15612MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMC4 Protein
+Inquiry
Cat.#:SMC4-4340RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SMC4 Protein, His-tagged
+Inquiry
Cat.#:SMC4-6087CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SMC4
+Inquiry
Cat.#:SMC4-9527ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMC4
+Inquiry
Cat.#:SMC4-1649HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SMC4 cell lysate
+Inquiry

Involved Pathway

SMC4 involved in several pathways and played different roles in them. We selected most pathways SMC4 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aurora B signaling
CBX5; RACGAP1; CDCA8; KIF20A; NCAPH; AURKB; NSUN2; SEPT1; TACC1; PEBP1
Cell Cycle
GINS4; CLSPN; CSNK1E; NPM1; TP53BP1; NDE1; STIL; MCM6; SMAD3; YWHAE
Cell Cycle, Mitotic
DYNC1H1; LIN37; NEDD1; HAUS2; ZWILCH; CSNK2A2; USO1; SET; NCAPG2; MCM8
Condensation of Prometaphase Chromosomes
NCAPG; SMC2; CSNK2A2; NCAPH; NCAPD2; CSNK2A1; CSNK2B; SMC4
Condensation of Prophase Chromosomes
H3F3D; SETA; NCAPD3; H3F3B.1; SET; NCAPH2; PHF8; SETB; SMC4; NCAPG2
M Phase
KIF2B; GORASP2; ARPP19; BLZF1; PMF1; ZW10; MCPH1; ARPP19B; PDS5A; NEK6
Mitotic Prometaphase
AHCTF1; CENPO; CENPK; CENPI; SGOL1; CLIP1; NCAPH; MIS12; NDEL1B; SKA1
Mitotic Prophase
SMC4; NCAPD3; GORASP2; CNEP1R1; NEK6; PHF8; ENSA; ARPP19B; SETB; BLZF1

Protein Function

SMC4 has several biochemical functions, for example, ATP binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC4 itself. We selected most functions SMC4 had, and list some proteins which have the same functions with SMC4. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein HYOU1; TOR1L3; ULK4; ITPK1; PSMC1; MAT2AA; SMYHC2; PIM1; ABCB3L1; DDX39
Function protein binding
Related Protein KIAA1109; RIPPLY2; PCNP; WDR74; RPS27A; FAM188A; KCNJ15; ABHD1; NEDD4; AHI1
Function protein heterodimerization activity
Related Protein MAFGB; F11R.1; PIK3R1; OSTA; AHR; HIST1H4B; ITGB1; HMG20A; PPARD; ATF1

Interacting Protein

SMC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC4.
MYC; SMC2; NCAPH; MCC; CASP4; IKBKE; NCAPH2; SMYD2; PHLDA3; IKBKG; hmuT; tgt; metE; mtlR; hemH2