smc4
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  • Official Full Name
  • structural maintenance of chromosomes 4
  • Background
  • Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi
  • Synonyms
  • SMC4; structural maintenance of chromosomes 4; SMC4 (structural maintenance of chromosomes 4, yeast) like 1 , SMC4 structural maintenance of chromosomes 4 like 1 (yeast) , SMC4L1; structural maintenance of chromosomes protein 4; CAP C; hCAP C; SMC protein 4; XCAP-C homolog; chromosome-associated polypeptide C; SMC4 structural maintenance of chromosomes 4-like 1; CAPC; CAP-C; SMC-4; SMC4L1; hCAP-C
Cat.#:SMC4-2811HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMC4, GST-tagged
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Cat.#:SMC4-15612MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMC4 Protein
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Cat.#:SMC4-4340RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SMC4 Protein, His-tagged
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Cat.#:SMC4-6087CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SMC4
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Cat.#:SMC4-9527ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMC4
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Cat.#:SMC4-1649HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SMC4 cell lysate
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Involved Pathway

SMC4 involved in several pathways and played different roles in them. We selected most pathways SMC4 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aurora B signaling
CBX5; PEBP1; AURKC; NSUN2; CENPA; AURKB; CDCA8; NCAPH; INCENP; EVI5
Cell Cycle
ANKLE2; CDKN2A; TGFB1; CDC25C; CENPK; KNTC1; NDE1; DNA2; CUL1B; LIN54
Cell Cycle, Mitotic
CEP78; CEP57; KIF18A; MAU2; HIST2H3C; NUMA1; MAPRE1; FGFR1OP; LMNB1; NUP50
Condensation of Prometaphase Chromosomes
NCAPG; NCAPD2; CSNK2B; CSNK2A2; SMC4; SMC2; NCAPH; CSNK2A1
Condensation of Prophase Chromosomes
SETA; H3F3B.1; NCAPG2; SET; NCAPD3; SMC2; MCPH1; SMC4; NCAPH2; PHF8
M Phase
NEK9; CTDNEP1A; SPDL1; CCDC99; NDEL1A; NIPBLA; SPC25; SMC4; NCAPG2; TMPO
Mitotic Prometaphase
B9D2; RCC2; NUDC; NUF2; CCDC99; SMC4; ZWILCH; DSN1; NCAPH; CENPQ
Mitotic Prophase
SET; MCPH1; SMC2; NEK7; MASTL; ARPP19B; SETA; ARPP19; VRK1; NEK6

Protein Function

SMC4 has several biochemical functions, for example, ATP binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC4 itself. We selected most functions SMC4 had, and list some proteins which have the same functions with SMC4. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein NOLC1; LTK; DGKD; IARS; ACSL4; CDC42BPB; MAP2K4B; NME2B.2; CHD6; PLK5
Function protein binding
Related Protein SALL2; USF2; BCOR; SPSB4; Fgf15; PRAP1; MYH9; FGF19; WDR48; LARP4
Function protein heterodimerization activity
Related Protein TOP2B; UBA3; H2AFB2; SLC51A; WHRN; Defa-rs7; TYRP1; BCL2A; TLR6; ITGA3

Interacting Protein

SMC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC4.
MYC; SMC2; NCAPH; MCC; CASP4; IKBKE; NCAPH2; SMYD2; PHLDA3; IKBKG; hmuT; tgt; metE; mtlR; hemH2