SMC4
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Official Full Name
structural maintenance of chromosomes 4
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Overview
Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi -
Synonyms
SMC4; structural maintenance of chromosomes 4; SMC4 (structural maintenance of chromosomes 4, yeast) like 1 , SMC4 structural maintenance of chromosomes 4 like 1 (yeast) , SMC4L1; structural maintenance of chromosomes protein 4; CAP C; hCAP C; SMC protein 4; XCAP-C homolog; chromosome-associated polypeptide C; SMC4 structural maintenance of chromosomes 4-like 1; CAPC; CAP-C; SMC-4; SMC4L1; hCAP-C;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E. coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SMC4-2811H | Recombinant Human SMC4, GST-tagged | E. coli | GST | ||
| Human | SMC4-1649HCL | Recombinant Human SMC4 cell lysate | N/A |
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| Mouse | SMC4-15612M | Recombinant Mouse SMC4 Protein | Mammalian Cell | His |
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| Mouse | SMC4-8470M | Recombinant Mouse SMC4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | SMC4-8470M-B | Recombinant Mouse SMC4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | SMC4-4340R | Recombinant Rhesus monkey SMC4 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | SMC4-4156R | Recombinant Rhesus Macaque SMC4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | SMC4-4156R-B | Recombinant Rhesus Macaque SMC4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | SMC4-9527Z | Recombinant Zebrafish SMC4 | Mammalian Cell | His |
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| Chicken | SMC4-6087C | Recombinant Chicken SMC4 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
SMC4 involved in several pathways and played different roles in them. We selected most pathways SMC4 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aurora B signaling | TACC1;INCENP;RACGAP1;CBX5;DES;AURKC;KIF2C;EVI5;SGOL1 |
| Cell Cycle | MSH4;E2F6;MAU2;TFDP1A;CENPO;VRK1;MCM8;CSNK2A1;NCAPG |
| Cell Cycle, Mitotic | MCPH1;CEP290;CDK5RAP2;CENPH;NCAPH;FGFR1OP;DCTN1A;CEP57;B9D2 |
| Condensation of Prometaphase Chromosomes | CSNK2B;CSNK2A2;CSNK2A1;NCAPH;NCAPD2;SMC2;SMC4;NCAPG |
| Condensation of Prophase Chromosomes | SMC2;SETA;SET;H3F3B.1;NCAPH2;SMC4;H3F3D;NCAPD3;NCAPG2 |
| M Phase | STAG1;MAU2;APITD1;KIF18A;SET;RANGAP1B;GORASP1;TMPO;NDEL1A |
| Mitotic Prometaphase | SGOL1;CENPQ;CDCA8;SKA1;ZWILCH;CENPN;MIS12;SMC2;SKA2 |
| Mitotic Prophase | MCPH1;PHF8;BLZF1;ARPP19B;CTDNEP1B;NEK9;NEK7;VRK1;ENSA |
SMC4 has several biochemical functions, for example, ATP binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC4 itself. We selected most functions SMC4 had, and list some proteins which have the same functions with SMC4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATAD2;RTEL1;GK2;CAMK4;AKT2L;HSPD1;TYRO3;MAPK14;ABCE1 |
| protein binding | GZMA;CCDC151;HP1BP3;RXRG;VPREB1;CD244;GRID2IP;ZFAND2B;TAC1 |
| protein heterodimerization activity | CA;DMRT3A;ADORA2A;BCL2L10;FLOT1;HIF1A;PHC2B;SMC4;LIMK1 |
SMC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC4.
MYC; SMC2; NCAPH; MCC; CASP4; IKBKE; NCAPH2; SMYD2; PHLDA3; IKBKG; hmuT; tgt; metE; mtlR; hemH2
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